All Articles Tagged As: melanoma

Common Laser Surgery Used In Uncommon Cancer (6/26/2008)

During a routine eye exam earlier this year, Mike Samogala learned he had a rare form of cancer known as melanoma of the eye. Because the cancer was so advanced, surgeons had to remove his eye to save his life. ...> Full Article

Patient's own infection-fighting T cells put late-stage melanoma into long-term remission - without chemotherapy or radiation (6/23/2008)

Case is first to show safety and effectiveness of using cloned cells alone to kill tumors ...> Full Article

New combination therapy safe, promising for melanoma patients (6/2/2008)

The combination of two different biotherapies may be beneficial for patients with inoperable melanoma ...> Full Article

Targeted therapy plus chemotherapy may pack 1-2 punch against melanoma (5/18/2008)

By targeting and disabling a protein frequently found in melanoma tumors, doctors may be able to make the cancer more vulnerable to chemotherapy ...> Full Article

Scientists identify interacting proteins key to melanoma development (5/7/2008)

Researchers have discovered how a mole develops into melanoma by showing the interaction of two key proteins involved in 60-70 percent of tumors ...> Full Article

Melanoma Lurks in Larger Skin Lesions, Researchers Find (4/26/2008)

Skin lesions that are about the size of a pencil eraser are more likely to be melanomas, a deadly form of skin cancer, than smaller moles ...> Full Article

Protein in embryonic stem cells control malignant tumor cells (3/5/2008)

A protein that governs development of human embryonic stem cells (hESCs) also inhibits the growth and spread of malignant melanoma, the deadliest skin cancer, Northwestern University researchers have discovered. Metastatic melanoma, which develops from the transformation of skin pigment cells or melanocytes, has a death rate of more than 80 percent and a median survival of less than 7.5 months. ...> Full Article

Researchers add further weight to link between cancer and obesity (2/18/2008)

Researchers from the University of Manchester, Christie Hospital and University of Bern in Switzerland have today published findings in the Lancet medical journal which further support the link between obesity and risk of developing cancer. ...> Full Article

Genome-Wide Survey Nets Key Melanoma Gene (2/11/2008)

One might call it a tale of two melanocytes. Given the same genetic mutation, why does one melanocyte shut down growth and become a relatively benign mole, while another rages out of control and develops into deadly melanoma? ...> Full Article

Melanomas May Appear Noticeably Different Than Other Moles (1/22/2008)

A preliminary study suggests that melanomas have a different appearance than other irregular skin moles (i.e., are "ugly ducklings"), according to a report in the January issue of Archives of Dermatology, one of the JAMA/Archives journals. ...> Full Article

Something new under the sun (1/11/2008)

Generation Y is becoming more complacent about the risk of melanoma and other types of skin cancer, according to a University of New South Wales (UNSW) researcher. ...> Full Article

Studies New Treatment for Advanced Melanoma (12/22/2007)

researchers are evaluating the safety and effectiveness of Allovectin-7, an investigational treatment for advanced melanoma. ...> Full Article

Cancer drug works by stimulating cancer gene (11/21/2007)

Melanoma tumors carry enemy within, suggesting new treatment strategy ...> Full Article

Predicting melanoma spread (10/19/2007)

A new online tool will allow doctors to predict how melanoma can spread around the body. ...> Full Article

Immunity Booster May Slow Metastatic Melanoma (9/11/2007)

Cases of metastatic melanoma have increased by 690 percent in the past 50 years, yet few life-extending treatments are available for people diagnosed with the disease. ...> Full Article

Melanoma Drug Revs Immune Cells But Cancer Cells Ignore It (9/5/2007)

A new study shows that an important drug used in the treatment of malignant melanoma has little effect on the melanoma cells themselves. Instead, it activates immune-system cells to fight the disease. ...> Full Article

Melanoma: Gene Signature Spells Poor Outcome (9/3/2007)

Other than visually inspecting the disease, doctors have no genetic blueprint to classify melanomas, a lethal form of skin cancer. Tumors generally are ranked by how deeply the growth has invaded underlying skin tissue. The deeper it burrows into the skin, the more lethal the cancer, but some patients defy the odds and survive with thick tumors or die from thin ones. ...> Full Article

Protein Plays Role in Increased Skin Pigmentation (8/14/2007)

Researchers have identified a protein that plays an important, early role in the increase of protective skin pigmentation after exposure to ultraviolet (UV) radiation. The protein, called SOX9, is a transcription factor known to participate in embryo development and to be expressed in many adult tissues including the heart, kidney, and brain. ...> Full Article

Sunlight Has Dual Roles In Cancer Risk (6/24/2007)

New thesis explores the mechanisms of programmed cell death and melanoma malignum. ...> Full Article

Sun Exposure Early In Life Linked To Specific Skin Cancer Gene Mutation (6/12/2007)

Skin cancers often contain different gene mutations, but just how these mutations contribute to the cause of melanomas has been a mystery. ...> Full Article

Study Shows Combination Chemotherapy and VEGF Blocker Improves Progression-free Survival of Metastatic Melanoma Patients (6/9/2007)

Two chemotherapy drugs combined with an agent that prevents the growth of blood vessels significantly delayed the spread of tumors in patients with metastatic melanoma, according to study findings presented today at the 2007 American Association of Clinical Oncology (ASCO) Annual Meeting. ...> Full Article

UNC scientists discover cellular 'SOS' signal in response to UV skin damage (3/17/2007)

New research from the University of North Carolina at Chapel Hill School of Medicine has identified two proteins that may help protect against skin cancer. ...> Full Article

Molecular Differences Between Early and Advanced Melanomas Could Provide New Drug Targets (3/16/2007)

The cell-signaling molecule Akt is a primary trigger that leads malignant melanomas on the skin's surface to begin growing vertically beneath the skin and turn into deadly invasive cancers, scientists have found. Understanding this key molecular difference between radial melanomas that spread on the surface of the skin and melanomas that grow vertically and invasively could provide new targets for the development of drugs to treat individuals with advanced stage melanomas. ...> Full Article

Researchers test vaccines with dendritic cells on patients with melanoma, hepatoma and renal cell carcinoma (3/7/2007)

A team from the University Hospital and the Center for Applied Medical Research (CIMA) of the University of Navarra plans to carry out tests midway through 2007. ...> Full Article