All Articles Tagged As: hiv

Personalized immunotherapy to fight HIV/AIDS (8/16/2008)

Researchers adopt an innovative approach to fight the virus responsible for AIDS ...> Full Article

An overlooked tool in the battle against HIV/AIDS (8/10/2008)

The links between HIV transmission and the degree to which people are able to adopt realistic plans to achieve future projects, in other words, hope, have been overlooked in policies to tackle HIV/AIDS. New research argues that hope is a powerful tool in the battle to stop the spread of HIV/AIDS. ...> Full Article

Researchers halt spread of HIV with RNAi (8/8/2008)

Hopes languished last September when a promising candidate HIV vaccine failed to work. Despite this setback, many researchers still believe immunization is possible, and a new study suggests they're correct - at least at the cellular level. ...> Full Article

Study shows why treatment isn't effective for HIV (8/8/2008)

New research shows scarring occurs quickly in gut, limiting drug effectiveness ...> Full Article

How 'hidden mutations' contribute to HIV drug resistance (8/3/2008)

Researchers explain how previously ignored parts of HIV genome play key role ...> Full Article

Life expectancy of HIV patients increases (7/28/2008)

HIV-infected patients in high income countries are living some 13 years longer thanks to improvements in combination antiretroval therapy ...> Full Article

Viral recombination another way HIV fools the immune system (7/22/2008)

Immune system pressure can lead to selection of more potent strains ...> Full Article

Genetic cause of innate resistance to HIV/AIDS (7/21/2008)

Researchers demonstrate how 2 specific genes are involved in an innate resistance to HIV infection ...> Full Article

HIV Conquers Immune System Faster than Previously Realized (7/21/2008)

New research into the earliest events occurring immediately upon infection with HIV-I shows that the virus deals a stunning blow to the immune system earlier than was previously understood. ...> Full Article

Since Introduction Of Highly Active Antiretroviral Therapy, Death Rate For Hiv-Infected Persons Has Decreased (7/4/2008)

In industrialized countries, persons infected sexually with HIV now appear to experience mortality rates similar to those of the general population in the first 5 years following infection, though a higher risk of death remains as the duration of HIV infection lengthens ...> Full Article

Zinc Finger Proteins Put Personalized HIV Therapy Within Reach (7/1/2008)

Researchers Modify T-Cell Receptor Gene to Develop New Type of AIDS Treatment ...> Full Article

New Approach to HIV Vaccine Research (6/28/2008)

A new national effort to create a vaccine against HIV will include work by a University of Rochester Medical Center rheumatologist who is an expert on a portion of the immune system that has sometimes gotten short shrift in the fight against HIV. ...> Full Article

Oestrogen applied to the human penis could stop the spread of HIV (6/5/2008)

In a world first, a new study has shown that topical oestrogen could help prevent HIV infection by blocking entry of the virus into the human penis. ...> Full Article

New HIV browser gives researchers access to valuable data from vaccine trials (5/30/2008)

A new HIV data browser will give researchers access to a wealth of data collected during clinical trials of an AIDS vaccine ...> Full Article

Protein Provides Innate Defense Against HIV (5/28/2008)

By identifying a protein that restricts the release of HIV-1 virus from human cells, scientists believe they may be closer to identifying new approaches to treatment ...> Full Article

Study Finds Unique HIV Vaccine Formula Elicits Strong Immune Responses (5/27/2008)

Investigators express hope for HIV vaccine research with an alternative strategy ...> Full Article

Scientists image a single HIV particle being born (5/26/2008)

By using a specialized microscope that only illuminates the cell's surface, they have become the first to see, in real time and in plain view, hundreds of thousands of molecules coming together in a living cell to form a single particle of the virus that has, in less than 25 years, claimed more than 25 million lives: HIV. ...> Full Article

HIV-1 Immune Comback Tied to Genetic Mutations (5/24/2008)

A new study provides compelling evidence that two genes are responsible for the course of immune restoration in HIV-positive individuals undergoing virus-suppressing therapy ...> Full Article

Researchers Describe How Vaccine Adjuvant Jump-Starts Immune System (5/24/2008)

Researchers have determined how a key component of many vaccines activates an immune system response, a finding that opens up promising new avenues of research on better ways to prevent infections. ...> Full Article

DNA vaccines get a boost from dendritic cells (5/20/2008)

Researchers targeting HIV antibody proteins directly to the coordinating cells of the immune system. ...> Full Article

Compound has potential for new class of AIDS drugs (5/17/2008)

Researchers have developed what they believe is the first new mechanism in nearly 20 years for inhibiting a common target used to treat all HIV patients, which could eventually lead to a new class of AIDS drugs. ...> Full Article

Major shift in HIV prevention priorities needed (5/11/2008)

Researchers say reducing multiple sexual partnerships and providing male circumcision services should be emphasized ...> Full Article

Computer game's high score could earn the Nobel Prize in medicine (5/9/2008)

Gamers have devoted countless years of collective brainpower to rescuing princesses or protecting the planet against alien invasions. This week researchers at the University of Washington will try to harness those finely honed skills to make medical discoveries, perhaps even finding a cure for HIV. ...> Full Article

Molecular espionage shows a single HIV enzyme's many tasks (5/8/2008)

Reverse transcriptase, target of major anti-HIV drugs, dynamically binds both DNA, RNA ...> Full Article

Immune exhaustion in HIV infection (5/6/2008)

2 articles discussing immune exhaustion and its prevention in HIV infection ...> Full Article

Researchers synthesize compound to flush HIV out of hiding and into crosshairs (5/3/2008)

Researchers have found a way to synthesize better agents that can be tailored to flush HIV out into the open where the immune system and antiretroviral therapies can destroy it. ...> Full Article

Research Findings Open New Front in Fight against AIDS Virus (5/1/2008)

Human Protein May Offer Novel Target for Blocking HIV Infection ...> Full Article

Researcher's HIV Findings May Lead to New Treatment Strategies (4/24/2008)

In a surprising finding, researchers have discovered that HIV can cause portions of the body's innate immune system, when stimulated, to actually increase the virus' replication. ...> Full Article

Expansion of a monocyte subset in HIV patients could serve as a biomarker for progression of the disease (3/31/2008)

Amount of monocytes may indicate at what stage the virus is in. ...> Full Article

Research promising for cystic fibrosis (3/23/2008)

May serve as model for HIV therapies ...> Full Article

Researchers discover how stealthy HIV protein gets into cells (3/20/2008)

>Scientists have known for more than a decade that a protein associated with the HIV virus is good at crossing cell membranes, but they didn't know how it worked. A multidisciplinary team from the University of Illinois has solved the mystery, and their findings could improve the design of therapeutic agents that cross a variety of membrane types. ...> Full Article

Insight into HIV's 'On-Off' Switch Shows Promise for Therapy, Understanding Cellular Decisions (3/20/2008)

Researchers have discovered how a genetic circuit in HIV controls whether the virus turns on or stays dormant, and have succeeded in forcing the virus towards dormancy, a finding that shows promise as an avenue for HIV therapy ...> Full Article

In Novel Strategy Against AIDS, Einstein Researchers Genetically Engineer Immune Cells Into Potent Weapons for Battling HIV Infection (3/8/2008)

By outfitting immune-system killer cells with a new pair of genes, scientists at the Albert Einstein College of Medicine of Yeshiva University transformed them into potent weapons that destroy cells infected with HIV, the virus that causes AIDS. Their novel strategy of genetically engineering immune cells to redirect their infection-fighting ability toward killing HIV-infected cells could lead to an entirely new approach for combating AIDS and other viral diseases. ...> Full Article

Researchers discover gene that blocks HIV (3/5/2008)

A team of researchers at the University of Alberta has discovered a gene that is able to block HIV, and in turn prevent the onset of AIDS. ...> Full Article

HIV breakthrough: Researchers identify protein that fights immunodeficiency (3/4/2008)

A Canada-U.S. research team has solved a major genetic mystery: How a protein in some people's DNA guards them against killer immune diseases such as HIV. In an advance online edition of Nature Medicine, the scientists explain how the protein, FOX03a, shields against viral attacks and how the discovery will help in the development of a HIV vaccine. ...> Full Article

Research Scientists Devise Approach that Stops HIV at Earliest Stage of Infection (3/2/2008)

Unique Two-Step Process Based on Latest Viral Discoveries ...> Full Article

Protein In Deer Tick Saliva Prevents HIV-1 From Attaching To T Cells (2/24/2008)

The HIV-1 virus cripples the human immune system by targeting white blood cells called T cells that form the body's first line of defense in fighting infections. A recent study by researchers from the University of Massachusetts Amherst shows that a protein found in the saliva of deer ticks prevents the HIV-1 virus from attaching to the surface of T cells, which is the critical first step in the virus' attack strategy. ...> Full Article

Scientists Reactivate Immune Cell Production in HIV-Infected Adults (2/24/2008)

Scientists at the Gladstone Institute of Virology and Immunology (GIVI) and the University of California, San Francisco (UCSF) have found that therapy can be used to stimulate the production of vital immune cells, called "T- cells," in adults with HIV infection. ...> Full Article

Emerging infectious diseases are on the rise: Next target 'hotspot' predicted (2/21/2008)

It's not just your imagination. Providing the first-ever definitive proof, a team of scientists has shown that emerging infectious diseases such as HIV, Severe Acute Respiratory Syndrome (SARS), West Nile virus and Ebola are indeed on the rise. The team - including University of Georgia professor John Gittleman and scientists from the Consortium for Conservation Medicine, the Institute of Zoology (London) and Columbia University - recently published their findings in leading scientific journal Nature. ...> Full Article

HIV Persists in the Gut Despite Long-Term HIV Therapy--Second Study Finds that B-Cell Abnormalities Also Persist (2/17/2008)

Second Study Finds that B-Cell Abnormalities Also Persist ...> Full Article

New picture of HIV-1's protein jacket identifies attractive target for antibody-based vaccine (2/16/2008)

By coaxing the HIV-1 protein to reveal a hidden portion of its protein coat, scientists at Dana-Farber Cancer Institute and Harvard Medical School have provided a newly detailed picture of how protective, or so-called broadly neutralizing, antibodies block HIV-1 infection. ...> Full Article

Experimental HIV vaccine gets a boost from '70s-era discovery (2/14/2008)

Although science is known for being a forward-looking field, researchers have found that they can often benefit from a glance over their shoulders. By combining an experimental AIDS vaccine with a long-neglected molecule called poly-IC, Rockefeller University scientists discovered that they were able to significantly improve its effectiveness. Their new, bolstered vaccine not only stimulated the production of HIV-attacking immune cells in mice, but also allowed the rodents to maintain immunity over a significantly longer period of time. ...> Full Article

Scientists identify new cellular receptor for HIV (2/11/2008)

A cellular protein that helps guide immune cells to the gut has been newly identified as a target of HIV when the virus begins its assault on the body's immune system, according to researchers from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH). ...> Full Article

'Good Bacteria' in Women Give Clues for Slowing HIV Transmission (2/10/2008)

Beneficial bacteria found in healthy women help to reduce the amount of vaginal HIV among HIV-infected women and might make it more difficult for the virus to spread, boosting the possibility that "good bacteria" might someday be tapped in the fight against HIV. ...> Full Article

HIV drugs, Abacavir and Didanosine, increase the risk of heart attack (2/10/2008)

A study to assess the adverse effects of anti-retroviral drugs shows that two of the widely-used HIV drugs are associated with an increased risk of heart attack/the formation of blood clots in the heart. With the use of Didanosine; the risk of developing a heart attack increases by 49%, with Abacavir; the increased risk is 90%. The effect is most pronounced in patients with a high underlying cardiovascular risk. The research findings also show that the adverse effect is reversible, if patients discontinue use of these particular drugs. ...> Full Article

Herpes medication does not reduce risk of HIV infection in individuals with HSV-2, international study finds (2/7/2008)

An international clinical trial has found that acyclovir, a common medication for treating herpes simplex virus-2 (HSV-2), the most common cause of genital herpes, does not reduce the risk of HIV infection when taken by people infected with HSV-2. Multiple studies have shown that people with HSV-2 have a higher risk of acquiring HIV. Researchers had hoped that acyclovir's ability to suppress the herpes virus, and its associated genital sores and breaks in the skin, could cut down on the likelihood of HIV being transmitted to a person with HSV-2 during sexual intercourse. ...> Full Article

New Insights Into Vaccination For HIV (2/3/2008)

A group of Australian researchers at the Universities of Melbourne and New South Wales have developed new tools and paradigms to understand immune evasion from HIV. The study shows that both prior vaccination and timing influence the rates of immune escape, providing further insight into the effectiveness of T cell immunity to HIV. ...> Full Article

Anti-Parasite Drug Provides New Way to Attack HIV (2/2/2008)

Researchers Seek to Deny HIV Its Safe Havens in the Human Body ...> Full Article

Protein discovered that prevents HIV from spreading (1/21/2008)

In a study that could open up the field of virology to an entirely new suite of possibilities and that paves the way for future drug research, scientists at Rockefeller University and the Aaron Diamond AIDS Research Center have pinned down a molecule on the surface of human cells that helps keep particles of mutant strains of HIV from spreading. Rather than floating off to infect more cells, the protein contains the virus particles by keeping them attached to the parent cell's outer membrane, as if stuck there with glue. ...> Full Article

Researchers Reveal HIV Peptide's Possible Pathway Into the Cell (1/20/2008)

Discovery furthers push to develop healing uses for a deadly virus ...> Full Article

Existing Antiretroviral Drugs May Thwart Vaginal HIV Transmission, Researchers Report (1/18/2008)

Prescription drugs now used to treat human immunodeficiency virus infection in adults may prevent the vaginal transmission of HIV, researchers at UT Southwestern Medical Center have found. ...> Full Article

T-cell 'nanotubes' may explain how HIV virus conquers human immune system (1/16/2008)

String-like connections found between T-cells could be important to how HIV spreads between cells in the human immune system, according to new research published online today (13 January 2008) in Nature Cell Biology. The newly-discovered strands, named 'membrane nanotubes' by scientists, could help to explain how the HIV virus infects human immune cells so quickly and effectively. ...> Full Article

Researchers find cell protein that literally nips HIV in the bud (1/15/2008)

Researchers have found that a key protein in the body's dendritic cells can stop the virus that causes AIDS from "budding" - part of the virus' life cycle that is crucial to its ability to replicate and infect other cells. ...> Full Article

Genomic Screen Nets Hundreds Of Human Proteins Exploited By HIV (1/14/2008)

In some ways, HIV resembles a minimalist painter, using a few basic components to achieve dramatic effects. The virus contains just nine genes encoding 15 proteins, which wreak havoc on the human immune system. But this bare bones approach could have a fatal flaw. Lacking robust machinery, HIV hijacks human proteins to propagate, and these might represent powerful therapeutic targets. ...> Full Article

Clinical Trial to Assess Effects of Drug Regimens on HIV-Related Neuro-Cognitive Impairment (1/9/2008)

A clinical trial is being conducted by researchers at UCSD's HIV Neurobehavioral Research Center (HNRC) to discern which antiretroviral treatments are most effective in treating HIV-related disease in the brain and central nervous system. The study includes the use of novel functional magnetic resonance (fMRI) techniques to non-invasively image the brain changes underlying cognitive impairment due to HIV. ...> Full Article

Two Genes Are Important Key to Regulating Immune Response (12/31/2007)

Pbx-1, Prep-1 Help Spur IL-10 Production; Findings Have Implications for Research into Lupus, Cancer and HIV/AIDS ...> Full Article

Researcher helping Estonia develop system for HIV/AIDS (12/22/2007)

A researcher has received a grant from Estonia to develop a program to understand its burgeoning number of HIV/AIDS cases. ...> Full Article

Bringing Viruses Back to Life (12/17/2007)

It's a prospect that may unnerve some-scientists bringing extinct viruses back to life to learn more about how they evolved along with humans. But when it comes to retroviruses like HIV, which take up permanent residence in our DNA, the past can provide important clues about how to treat them. ...> Full Article

Cells use Velcro-like mechanism to keep viruses from spreading (12/9/2007)

Like mobsters, cells keep their friends close and their enemies - at least some of them - closer. According to new results from HIV researchers at Rockefeller University, one way that human cells prevent certain viruses from raging out of control is by blocking new viral particles from ever leaving an infected cell's surface. And, they believe, HIV thrives in part because it has evolved the ability to get around this obstacle. ...> Full Article

A New Protein Found in the Blood May Provide Relief from Neuropathic Pain (12/7/2007)

Neuropathic pain is caused by injury to the peripheral nerves in diseases such as HIV/AIDS, shingles, and cancer or in repetitive motion disorders and trauma, and does not respond well to conventional pain-relieving drugs. Research in rodents by scientists from the University of California, San Diego (UCSD) School of Medicine has provided evidence that a protein called LRP1 may help to ease neuropathic pain by blocking the response of glial cells that support and protect sensory neurons in the peripheral nervous system. Their findings, which could represent a novel target for neuropathic pain therapy, are published in the December 3 issue of the Journal of Clinical Investigation. ...> Full Article

UCSD Offers Free Test That Can Detect HIV as Early as One Week after Exposure (12/1/2007)

UC-San Diego's Antiviral Research Center (AVRC) is offering free and confidential HIV testing to people who may have a very recent infection with HIV, the retrovirus that can lead to AIDS. The Early Test Program - offered in collaboration with the San Diego County Health and Human Services Agency - offers a new test method that checks for the presence of the HIV virus, which can be detected within a week of infection. In contrast, a regular HIV test looks for antibodies in the blood, which can take three months or more to detect. ...> Full Article

Rebuilding The Evolutionary History Of HIV-1 Unravels A Complex Loop (11/29/2007)

An essential component of the human immunodeficiency virus (HIV-1) molecular machinery responsible for infecting cells consists of functionally-specialized layers, according to a study by investigators at the University of California San Diego Antiviral Research Center. ...> Full Article

Researchers Find Monkeys Able to Fend Off AIDS-like Symptoms with Enhanced HIV Vaccine (11/22/2007)

Researchers have discovered that using an immune system gene to enhance a vaccine used to study HIV in macaque monkeys provides the animals with greater protection against simian HIV (SHIV) than an unmodified vaccine. This multi-year study found that the addition of a molecule called Interleukin-15 effectively boosts the effects of a vaccine derived from the DNA of simian HIV. The study illustrates that DNA vaccine effectiveness can be improved by the inclusion of specific immune adjuvants, or helpers. ...> Full Article

Virus Used to Create Experimental HIV Vaccines Directly Impairs the Immune Response (11/19/2007)

Leading efforts to create an HIV vaccine have hinged on the use of viruses as carriers for selected elements of the HIV virus. Recently, however, evidence has emerged that some of these so-called viral vector systems may undermine the immune system and should not be used for vaccine development. Now, a new study from scientists at The Wistar Institute provides strong support for the idea that some viral-vector vaccines may cause more harm than good. ...> Full Article

Researchers Suggest Updating Criteria for HIV-associated Neurocognitive Disorders (11/12/2007)

After 10 years since the introduction of highly active antiretroviral therapy (HAART), the criteria for classifying HIV-related neurocognitive disorders may need to be revised and updated, according to a working group designated by NIMH and the National Institute of Neurological Disorders and Stroke to study the issue. The study was published October 30, 2007, in the journal Neurology. ...> Full Article

New HIV Vaccine Target Could Solve Mutation Problem (11/12/2007)

Researchers have identified a potential new way of fighting against HIV infection that relies on the remnants of ancient viruses, human endogenous retroviruses (HERV), which have become part of the genome of every human cell. ...> Full Article

Fine-tuning lasers to destroy blood-borne diseases like AIDS (11/9/2007)

Physicists have designed a revolutionary laser technique which can destroy viruses and bacteria such as AIDS without damaging human cells and may also help reduce the spread of hospital infections such as MRSA. ...> Full Article

Study Shows What Works In Treating HIV-Infected African Children (10/30/2007)

Providing HIV combination antiretroviral drug therapy is key to saving the lives of African children infected with the disease. ...> Full Article

Pace of AIDS progression not dependent on viral load alone (10/25/2007)

Armed with genetic information from more than 3,500 HIV-1-infected subjects and healthy individuals, a large multidisciplinary team from The University of Texas Health Science Center at San Antonio; the U.S. military; Massachusetts General Hospital/Harvard; The University of California, San Francisco; Australia; Colombia; and Argentina reported this week that two genes influence AIDS progression rates by affecting not just the extent of viral replication but also the strength of the body's immune response. ...> Full Article

Researchers knock out HIV (10/22/2007)

With the latest advances in treatment, doctors have discovered that they can successfully neutralise the HIV virus. The so-called 'combination therapy' prevents the HIV virus from mutating and spreading, allowing patients to rebuild their immune system to the same levels as the rest of the population. To date, it represents the most significant treatment for patients suffering from HIV. ...> Full Article

Matching Pathogens To Their Antibodies: Could Lead To HIV Vaccine (10/18/2007)

The search for a vaccination against HIV has been in progress since 1984, with very little success. Traditional methods used for identifying potential cellular targets can be very costly and time-consuming. ...> Full Article

Researchers track genetic journey of HIV from birth to death (10/17/2007)

Scientists have discovered how HIV evolves over the course of a person's lifetime into a more deadly form that heralds the onset of full-blown AIDS. The findings could pave the way for new therapeutic agents that target the virus earlier in the disease process, before it takes a lethal turn, researchers say. ...> Full Article

New class of drug offers hope to treatment-resistant AIDS patients (10/12/2007)

For the estimated millions of AIDS patients worldwide who are resistant or are developing resistance to currently available medicines, a discovery by a University of Georgia researcher may offer a new treatment option by targeting a previously elusive enzyme in the complex retrovirus responsible for the devastating disease. ...> Full Article

Feline Virus, Antiviral Drug Studied To Understand Drug Resistance (10/11/2007)

Researchers at Ohio State will spend the next two years testing their theories about just how an AIDS-like virus in cats is able to resist the powerful medicines that are thrown against it. ...> Full Article

Drug Cocktail Stops Brain Damage Caused by HIV (10/9/2007)

A combination of drugs widely used to treat infections caused by HIV appears to stop brain damage caused by the virus as well. ...> Full Article

MicroRNAs may be key to HIV's ability to hide, evade drugs (10/1/2007)

Tiny pieces of genetic material called microRNA (miRNA), better known for its roles in cancer, could be a key to unlocking the secrets of how HIV, the AIDS virus, evades detection, hiding in the immune system. Researchers at Jefferson Medical College in Philadelphia have shown that when an individual infected with HIV receives a powerful cocktail of antiviral agents called HAART (highly active antiretroviral therapy), the virus calls on miRNAs to help it remain quiet and practically undetectable, temporarily shutting down its ability to replicate and infect. ...> Full Article

Second pathway behind HIV-associated immune system dysfunction identified (10/1/2007)

Researchers may have discovered a second molecular "switch" responsible for turning off the immune system's response against HIV. Last year members of the same team identified a molecule called PD-1 that suppresses the activity of HIV-specific CD8 T cells that should destroy virus-infected cells. Now the researchers describe how a regulatory protein called CTLA-4 inhibits the action of HIV-specific CD4 T cells that control the overall response against the virus. ...> Full Article

Immunizations Are Discontinued in Two HIV Vaccine Trials (9/24/2007)

HIV Vaccine trials canceled after participants taking the vaccines became infected with HIV at a higher rate than those participants taking a placebo. ...> Full Article

Using Antiretrovirals as a Prevention Strategy Could Dramatically Slow The Spread of HIV Infection in Africa (9/21/2007)

Model predicts potential prevention of more than 3 million new HIV infections over 10 years ...> Full Article

HIV Protease Inhibitors Show AntiCancer Potential (9/6/2007)

Several protease inhibitors that are used in combination with other drugs to treat Human Immunodeficiency Virus (HIV) infection may also be effective against certain types of cancer, according to researchers from the National Cancer Institute (NCI), part of the National Institutes of Health. Nelfinavir (Viracept®), Ritonavir (Norvir®), and Saquinavir (Invirase®) inhibited growth of several types of cancer cells, with Nelfinavir being the most effective. These results appear in the September 1, 2007 issue of Clinical Cancer Research. ...> Full Article

Novel HIV Vaccine Funded for Clinical Development (9/2/2007)

A promising new HIV vaccine created at The Wistar Institute has received funding for clinical development aimed at moving the vaccine into human clinical trials as soon as possible. ...> Full Article

AIDS Interferes with Stem Cells in the Brain (8/17/2007)

Discovery links mechanism for HIV/AIDS dementia, possibly other neurological disorders, with known cancer "checkpoint" pathway ...> Full Article

Discovery in plant virus may help prevent HIV and similar viruses (8/10/2007)

In a study that could lead to new ways to prevent infection by human immunodeficiency virus (HIV) and similar organisms, Purdue University researchers have been able to genetically modify a plant to halt reproduction of a related virus. ...> Full Article

New Antiretroviral For HIV Patients Resistant To Other Drugs (8/4/2007)

International research carried out with the participation of researchers from the irsiCaixa Foundation and the HIV Unit of the University Hospital Germans Trias i Pujol, both directed by UAB associate lecturer Bonaventura Clotet, has demonstrated the efficiency of etravirine (TMC125), a new antiretroviral drug, on patients who are resistant to others drugs. The results of this research have been published in two different articles in The Lancet. ...> Full Article

News Clinical Study Of Promising Microbicide For HIV Prevention (8/2/2007)

Physicians at the University of South Florida Department of Pediatrics have begun a clinical trial of a topical vaginal microbicide that holds great promise for preventing the sexual transmission of the human immunodeficiency virus (HIV). ...> Full Article

Sex-Trafficked Girls And Women From South Asia Have High Prevalence Of HIV Infection (8/2/2007)

Nearly 40 percent of repatriated Nepalese sex-trafficked girls and women tested were positive for HIV infection, with girls trafficked before age 15 having higher rates of infection, according to a study in the August 1 issue of JAMA, a theme issue on violence and human rights. ...> Full Article

Study Helps Explain How HIV Becomes AIDS (8/1/2007)

Finding could help scientists seeking therapies to block virus progression ...> Full Article

Treating HIV-Infected Infants Early Helps Them Live Longer (7/30/2007)

Hundreds of thousands of babies around the world are born each year with HIV-more than half a million in 2006 alone. Caring for these children is complicated by the fact that their immune systems are not fully developed in the first year of life, which makes them especially susceptible to rapid HIV disease progression and death. The current standard of HIV care in many parts of the world is to treat infants with antiretroviral therapy-but only after they show signs of illness or a weakened immune system. ...> Full Article

Sex, Drugs and HIV (7/27/2007)

The rise in the number of Australian HIV cases in the past seven years is likely to be related to risky sexual behaviour in men having sex with men, according to work co-authored by UNSW researchers. ...> Full Article

Scientists Find Key HIV Protein Makes Cell Membranes Bend More Easily (7/25/2007)

Carnegie Mellon University scientists have made an important discovery that aids the understanding of why HIV enters immune cells with ease. The researchers found that after HIV docks onto a host cell, it dramatically lowers the energy required for a cell membrane to bend, making it easier for the virus to infect immune cells. The finding, in press in Biophysical Journal, will provide vital data to conduct future computer simulations of HIV dynamics to help further drug discovery and prevent deadly infections. ...> Full Article

First Genome-Wide Study of Infectious Disease Opens New Avenues for HIV Treatment, Vaccines (7/24/2007)

The first genome-wide association study of an infectious disease, conducted by an international group of researchers through the Center for HIV/AIDS Vaccine Immunology (CHAVI), has yielded a new understanding of why some people can suppress virus levels following HIV infection. "The clearer picture of host responses to the virus achieved through this examination of genomes could lead to improved HIV therapies and provides new targets for vaccine developers," says Elias A. Zerhouni, M.D., director of the National Institutes of Health (NIH). CHAVI, which is led by Barton Haynes, M.D., of Duke University, Durham, N.C., was established in 2005 by the National Institute of Allergy and Infectious Diseases (NIAID), part of the NIH. ...> Full Article

Clues to Future Evolution of HIV Come From African Green Monkeys (7/21/2007)

Monkey viruses related to HIV may have swept across Africa more recently than previously thought, according to new research from The University of Arizona in Tucson. ...> Full Article

Major Breakthrough In Understanding How Hiv Interferes With Infected Cell Division (7/16/2007)

Dr. Eric A. Cohen and his team will publish on Friday, July 13, in PLoS Pathogens a discovery that could lead to the development of a new class of drugs to combat HIV. ...> Full Article

Genetics Research Advances Possibility Of HIV Vaccine (7/10/2007)

A pioneering collaborative study has discovered how the HIV virus evades the human body's immune system. The research collaborative - involving scientists from the British Columbia Centre for Excellence in HIV/AIDS, Massachusetts General Hospital (MGH), Microsoft Research and Los Alamos National Laboratory - used highly computer-intensive, cutting-edge statistical research methods to investigate how the HIV virus mutates to escape the body's immune system. ...> Full Article

Research Predicts HIV Drug Reaction (7/8/2007)

Specialists at Leicester's hospitals are taking part in research that is improving care for people living with HIV. ...> Full Article

HIV Ejected From Cells With Engineered Enzyme (6/30/2007)

A new enzyme eradicates the AIDS-virus from the host-cell genome ...> Full Article

Ultra Deep Sequencing Identifies HIV Drug Resistance at Early Stage (6/20/2007)

Rare, previously undetectable drug-resistant forms of HIV have been identified by Yale School of Medicine researcher Michael Kozal, M.D., using an innovative genome sequencing technology that quickly detects rare viral mutations. ...> Full Article

How Sneaky HIV Escapes Cells (6/9/2007)

Like hobos on a train, HIV, the virus that causes AIDS, uses a pre-existing transport system to leave one infected cell and infect new ones, Hopkins scientists have discovered. Their findings, published in the June issue of Plos Biology, counter the prevailing belief that HIV and other retroviruses can only leave and enter cells by virus-specific mechanisms. ...> Full Article

When HIV And Liver Disease Co-Exist (6/6/2007)

Since successful antiretroviral therapies have made HIV a treatable condition, more HIV patients who are also infected with hepatitis B or C are experiencing the progression of their liver disease. In the face of this novel challenge, experts in the field convened to share information and opinions on the management of such patients. ...> Full Article

Researchers Find Broad-Spectrum Defense Against HIV-1 (6/1/2007)

New research conducted at the Uniformed Services University of the Health Sciences (USU) suggests that it may be possible to develop a vaccine that protects against the myriad strains of the HIV virus. ...> Full Article

Ohio State Chosen for Revamped HIV Clinical Trials Network (5/26/2007)

The National Institute of Allergy and Infectious Diseases (NIAID) has awarded a seven-year, multimillion-dollar grant to the Ohio State University Medical Center to continue testing new AIDS treatments, vaccines and prevention methods. ...> Full Article

New Study Finds HIV In Breastmilk Killed By Flash-Heating (5/25/2007)

A simple method of flash-heating breast milk infected with HIV successfully inactivated the free-floating virus, according to a new study led by researchers at the Berkeley and Davis campuses of the University of California. ...> Full Article

HIV's Effect On White Blood Cells Questioned By New Research (5/24/2007)

Scientists have refuted a longstanding theory of how HIV slowly depletes the body's capacity to fight infection, in new research published today. ...> Full Article

Researchers Find A Peptide That Encourages HIV Infection (5/11/2007)

UCLA AIDS Institute researchers have discovered that when a crucial portion of a peptide structure in monkeys that defends against viruses, bacteria and other foreign invaders is reversed, the peptide actually encourages infection with HIV. ...> Full Article

Scientists Discover How AIDS Infects Cell (5/7/2007)

Scientists provide new information about how HIV, the virus that causes AIDS, enters the nucleus of an infected cell. This study could help devise a new way to fight AIDS. ...> Full Article

Researchers Discover Cellular Factor Blocks HIV-1 Production (4/17/2007)

Researchers at Mayo Clinic have shown that a cellular factor restricts production of HIV-1 by actively degrading a viral protein. The findings appear in the online version of the journal Nature Medicine. ...> Full Article

New Study Finds an Altered Immune Response to Viruses Like HIV and Hepatitis C (4/12/2007)

After a viral infection, a small percentage of the T cells generated to kill virus-infected cells remain on guard to establish long-term immunity. These so-called memory T cells, which derive from a family of immune cells known as CD8 T cells, engage in a self-renewal process that is essential to their persistence. This ongoing process ensures effective protection against any repeat infection by the same virus, even decades later. ...> Full Article