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All Articles Tagged As: genome
Work of South Africa-US Research Team Gives First Look at Genome of XDR TB; Initial Analysis Highlights Small Number of DNA Differences Among Drug-resistant and drug-sensitive Microbes
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Scientists at MIT and the Technion Israel Institute of Technology have for the first time recorded the entire genomic expression of both a host bacterium and an infecting virus over the eight-hour course of infection.
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Scientists have developed a new method of capturing a complete genome-wide screening of blood vessel cells in their actual disease state, advancing the potential for genetic research on the tissue responsible for delivering nourishment that can accelerate the growth of both a cancer tumor or wound healing.
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Research on the DNA of 15 mouse strains commonly used in biomedical studies is expected to help scientists determine the genes related to susceptibility to environmental disease. The body of data is now publicly available in a catalog of genetic variants, which displays the data as a mouse haplotype map, a tool that separates chromosomes in to many small segments, helping researchers find genes and genetic variations in mice that may affect health and disease. The haplotype map appearing online in the July 29th issue of Nature is the first published full descriptive analysis of the "Mouse Genome Resequencing and SNP Discovery Project" conducted by the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health.
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The first genome-wide association study of an infectious disease, conducted by an international group of researchers through the Center for HIV/AIDS Vaccine Immunology (CHAVI), has yielded a new understanding of why some people can suppress virus levels following HIV infection. "The clearer picture of host responses to the virus achieved through this examination of genomes could lead to improved HIV therapies and provides new targets for vaccine developers," says Elias A. Zerhouni, M.D., director of the National Institutes of Health (NIH). CHAVI, which is led by Barton Haynes, M.D., of Duke University, Durham, N.C., was established in 2005 by the National Institute of Allergy and Infectious Diseases (NIAID), part of the NIH.
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 | In the event of a nuclear or radiological catastrophe -- such as a nuclear accident or a "dirty bomb" -- thousands of people would be exposed to radiation, with no way of quickly determining how much of the deadly substance has seeped inside their bodies. Scientists at Duke University Medical Center have developed a new blood test to rapidly detect levels of radiation exposure so that potentially life-saving treatments could be administered to the people who need them most. ...> Full Article |
 | Scientists at the Wellcome Trust Sanger Institute, where one-third of the human genome was sequenced, have now pioneered decoding the sequence of cancer genomes. They have carried out the broadest survey yet of the human genome in cancer by sequencing more than 250 million letters of DNA code, covering more than 500 genes and 200 cancers. ...> Full Article |
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