All Articles Tagged As: cervical cancer
Human papillomavirus type 16, the most common cause of cervical cancer, silences a key signaling molecule of immune response in its host cells. Once the body's own immune defense is missing, the pathogens are able to infect the cells of the cervical mucosa even more successfully. Scientists of the German Cancer Research Center have found out that the viral E6 oncogene is responsible for this mechanism.
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Cervical cancer patients with specific changes in the cancer genome have a three- or fourfold increased risk of relapse after standard treatment compared to patients without these changes, according to a study by Norwegian researchers published Nov. 13 in the open-access journal PLoS Genetics. The research suggests that specific genetic changes are crucial steps in the progression of the disease towards an aggressive and treatment-resistant state.
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Researchers at the University of Wisconsin-Madison School of Medicine and Public Health have eliminated cervical cancer in mice with two FDA-approved drugs currently used to treat breast cancer and osteoporosis.
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Although a wide spectrum of human papillomavirus is seen across the population of India, HPV-16 and HPV-18 are the most common types and a vaccination targeting these types could eliminate 75 percent of the cervical cancers in the region, according to data presented at the American Association for Cancer Research Frontiers in Basic Cancer Research Meeting.
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Mice and rabbits immunized with a multimeric-L2 protein vaccine had robust antibody responses and were protected from infection when exposed to human papillomavirus type 16 four months after vaccination, according to a new study published in the May 26 online issue of the Journal of the National Cancer Institute.
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Infection with anal human papillomavirus, a virus that can cause anal and cervical cancers, is associated with a higher risk of new HIV infection in previously HIV-negative men who have sex with men, according to new UCSF research
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DNA from human papilloma virus type 16 and HPV type 18 were found in the majority of invasive cervical cancers in New Mexico in the 1980s and 1990s, according to a population-based study published in the March 24 online issue of the Journal of the National Cancer Institute.
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Women with certain gene variations appear to be protected against cervical cancer, according to a study led by scientists at Albert Einstein College of Medicine of Yeshiva University and reported in Clinical Cancer Research.
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UAB researchers have developed a new, inexpensive and efficient method for producing and studying a type of human papillomavirus that causes cervical cancer. The process could speed understanding of how the virus functions and causes diseases, and lead to new prevention or treatment options.
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Perhaps surprisingly, the number of copies of the carcinogenic human papillomavirus type 18 (HPV18) relative to cellular DNA is not associated with the likelihood of progression to advanced precancerous lesions of the cervix, according to a study in the Jan. 27 online issue of the Journal of the National Cancer Institute.
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The human papillomavirus allows infected cervical and head and neck cancer cells to maintain internal molecular conditions that make the cancers resistant to therapy and more likely to grow and spread, resulting in a poor prognosis for patients, researchers with UCLA's Jonsson Cancer Center found.
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Immigrant women have a higher risk of developing the disease than Swedish-born women
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The virus responsible for most cases of cervical cancer has a serious weakness which may provide hope for new treatments for the disease.
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