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All Articles Tagged As: cancerSelenium intake may worsen prostate cancer in some, study reports (7/1/2009)Higher selenium levels in the blood may worsen prostate cancer in some men who already have the disease. A higher risk of more-aggressive prostate cancer was seen in men with a certain genetic variant. In those subjects, having a high level of selenium in the blood was associated with a two-fold greater risk of poorer outcomes than men with the lowest amounts of selenium. ...> Full Article Second gene linked to familial testicular cancer (6/30/2009)Specific variations or mutations in a particular can gene raise a man's risk of familial, or inherited, testicular germ-cell cancer, the most common form of this disease, according to new research by scientists at the National Institutes of Health. This is only the second gene to be identified that affects the risk of familial testicular cancer, and the first gene in a key biochemical pathway. The study appears in the July 2009 Cancer Research. ...> Full Article Risk of cancer (6/30/2009)Scientists discover novel mechanism that increases the risk of common colorectal cancer ...> Full Article New piece found in colorectal cancer puzzle (6/29/2009)Prostasin, a relatively unknown protease enzyme expressed in most epithelial cells, may play a role in the genesis of colorectal cancer. Researchers writing in the open-access journal BMC Cancer have associated a reduction in the expression of inhibitors of the enzyme with malignant cellular behavior. ...> Full Article Study pinpoints novel cancer gene and biomarker (6/28/2009)Research underscores need to combine genomics and basic biology in cancer gene hunt ...> Full Article Controversial cancer stem cells offer new direction for treatment (6/26/2009)In a review in Science, a University of Rochester Medical Center researcher sorts out the controversy and promise around a dangerous subtype of cancer cells, known as cancer stem cells, which seem capable of resisting many modern treatments. ...> Full Article Dramatic outcomes in prostate cancer study (6/25/2009)Two Mayo Clinic patients whose prostate cancer had been considered inoperable are now cancer free thanks in part to an experimental drug therapy that was used in combination with standardized hormone treatment and radiation therapy. The men were participating in a clinical trial of an immunotherapeutic agent called MDX-010 or ipilimumab. ...> Full Article Research uncovers clues to virus-cancer link (6/24/2009)In a series of recently published articles, a research team from the University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center has uncovered clues to the development of cancers in AIDS patients. ...> Full Article Green tea may affect prostate cancer progression (6/24/2009)According to results of a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research, men with prostate cancer who consumed the active compounds in green tea demonstrated a significant reduction in serum markers predictive of prostate cancer progression. ...> Full Article Discovery of the cell's water gate may lead to new cancer drugs (6/20/2009)
Novel light-sensitive compounds show promise for cancer therapy (6/19/2009)Chemists at UC Santa Cruz have developed novel compounds that show promise for photodynamic cancer therapy, which uses light-activated drugs to kill tumor cells. The new compounds, called dye-sensitized ruthenium nitrosyls, are absorbed by cancer cells and respond to specific wavelengths of light by releasing nitric oxide, which triggers cell death. ...> Full Article Cancer researchers develop model that may help identify cancer stem cells (6/18/2009)Researchers at UCLA's Jonsson Comprehensive Cancer Center, on a quest to find lung cancer stem cells, have developed a unique model to allow further investigation into the cells that many believe may be at the root of all lung cancers. ...> Full Article RNA snippet suppresses spread of aggressive breast cancer (6/17/2009)Low levels of a tiny RNA fragment in cells are associated with metastatic breast cancer in humans and increases the aggressive spread of breast cancer in mice, according to researchers at Whitehead Institute for Biomedical Research. Measuring levels of this so-called microRNA in cancer cells may more accurately predict the likelihood of metastasis, the spread of cancer to other parts of the body that accounts for 90 percent of cancer-related deaths. ...> Full Article New skin cancer patch: Possible alternative to surgery (6/16/2009)A new study shows that a radioactive skin patch can safely and successfully treat basal cell carcinoma, one of the most common types of skin cancers, according to researchers at the SNM's 56th Annual Meeting. ...> Full Article Waste disposal protein is mechanism behind cancer tumor suppression (6/16/2009)Team at the Cancer Institute of New Jersey and Rutgers University focuses on cell self digestion pathway ...> Full Article Effective over-the-counter prostate cancer test kit likely in next few years (6/15/2009)
Research finds single gene controls growth of some cancers (6/14/2009)Research led by Ashok Aiyar, Ph.D., associate professor of microbiology at LSU Health Sciences Center New Orleans, showing that a single gene can control growth in cancers related to the Epstein-Barr virus and that existing therapeutics can inactivate it, will be published in the June 12, 2009, online issue of PLoS Pathogens. ...> Full Article Gene therapy technique thwarts cancer by cutting off tumor blood supply (6/14/2009)University of Florida researchers have come up with a new gene therapy method in mice implanted with human colorectal cancer cells to disrupt cancer growth by using a synthetic protein to induce blood clotting, cutting off a tumor's blood and nutrient supply. ...> Full Article Lost molecule is lethal for liver cancer cells in mice (6/13/2009)
Cancer: The cost of being smarter than chimps? (6/12/2009)
MicroRNA replacement therapy may stop cancer in its tracks (6/12/2009)A new study suggests that delivering small RNAs, known as microRNAs, to cancer cells could help to stop the disease in its tracks. microRNAs control gene expression and are commonly lost in cancerous tumors. Researchers have shown that replacement of a single microRNA in mice with an extremely aggressive form of liver cancer can be enough to halt their disease, according to a report in the June 12 issue of the journal Cell, a Cell Press publication. ...> Full Article Vaporized viral vector shows promise in anti-cancer gene therapy (6/11/2009)A new lung cancer therapy employing a vaporized viral vector to deliver a cancer-inhibiting molecule directly to lung tissue shows early promise in mouse trials, according to researchers at the Ministry of Education, Science and Technology in Korea. ...> Full Article Hormone therapy may confer more aggressive properties to prostate tumors (6/11/2009)
Gene activity reveals dynamic stroma microenvironment in prostate cancer (6/10/2009)As stroma -- the supportive framework of the prostate gland -- react to prostate cancer, changes in the expression of genes occur that induce the formation of new structures such as blood vessels, nerves and parts of nerves, said researchers at Baylor College of Medicine in a report that appears in the current issue of the journal Clinical Cancer Research. ...> Full Article Link unraveled between chromosomal instability and centrosome defects in cancer cells (6/9/2009)In a new study, Dana-Farber Cancer Institute scientists disprove a century-old theory about why cancer cells often have too many or too few chromosomes, and show that the actual reason may hold the key to a novel approach to cancer therapy. ...> Full Article Scientists uncover mode of action of enzyme linked with several types of cancer (6/8/2009)Scientists at the Institute for Research in Immunology and Cancer of the University of Montreal have discovered a key mechanism used by cells to efficiently distribute chromosomes to new cells during cell multiplication. ...> Full Article Study gives clues to how adrenal cancer forms (6/7/2009)
Improved DNA stool test could detect digestive cancers in multiple organs (6/6/2009)Mayo Clinic researchers have demonstrated that a noninvasive screening test can detect not only colorectal cancer but also the common cancers above the colon -- including pancreas, stomach, biliary and esophageal cancers. This is one of more than 100 Mayo Clinic studies being presented at Digestive Disease Week 2009 in Chicago, May 30 through June 4. ...> Full Article Researchers link pathway to breast cancer stem cells (6/6/2009)
Researchers discover genetic risk factor for testicular cancer (6/5/2009)Gene is associated with a three-fold increase in risk ...> Full Article Researchers identify gene that regulates tumors in neuroblastoma (6/4/2009)Virginia Commonwealth University researchers have identified a gene that may play a key role in regulating tumor progression in neuroblastoma, a form of cancer usually found in young children. Scientists hope the finding could lead to an effective therapy to inhibit the expression of this gene. ...> Full Article Stem cell protein offers a new cancer target (6/4/2009)A study led by Children's Hospital Boston stem cell researcher George Daley, M.D., Ph.D., shows that a protein that keeps embryonic stem cells in their stem-like state, called LIN28, is also important in cancer. It offers a new target to attack, especially in resistant and hard-to-treat cases. ...> Full Article Most common brain cancer may originate in neural stem cells (6/3/2009)Findings in mice suggest greater hope for targeting brain cancer, but also greater caution in pursuing stem cell treatments for degenerative diseases ...> Full Article Cancer researchers first to link intestinal inflammation with systemic chromosome damage (6/3/2009)UCLA scientists have linked for the first time intestinal inflammation with systemic chromosome damage in mice, a finding that may lead to the early identification and treatment of human inflammatory disorders, some of which increase risk for several types of cancer. ...> Full Article Study shows drug combination improves outcome for advanced non-small cell lung cancer (6/2/2009)A new, international study found that the combination of two drugs delays disease progression for patients with advanced non-small cell lung cancer. Results from the Phase III "ATLAS" trial were presented today by Dr. Vincent Miller of Memorial Sloan-Kettering Cancer Center at the American Society of Clinical Oncology Annual Meeting. ...> Full Article New broad-spectrum vaccine to prevent cervical cancer induces strong responses in animals (6/1/2009)Mice and rabbits immunized with a multimeric-L2 protein vaccine had robust antibody responses and were protected from infection when exposed to human papillomavirus type 16 four months after vaccination, according to a new study published in the May 26 online issue of the Journal of the National Cancer Institute. ...> Full Article The vulnerable cancer cell (5/31/2009)New studies reveal broad, hidden network that lets tumors thrive ...> Full Article Study may aid efforts to prevent uncontrolled cell division in cancer (5/31/2009)Researchers from the Ludwig Institute for Cancer Research at the University of California, San Diego School of Medicine have uncovered a remarkable property of the contractile ring, a structure required for cell division. Understanding how the contractile ring works to divide the cell may facilitate development of therapies to prevent uncontrolled cell division in cancer. ...> Full Article Carbohydrate restriction may slow prostate tumor growth (5/31/2009)Restricting carbohydrates, regardless of weight loss, appears to slow the growth of prostate tumors, according to an animal study being published this week by researchers in the Duke Prostate Center. ...> Full Article Cancer cells need normal, nonmutated genes to survive (5/30/2009)Cancer cells rely on normal, healthy genes as much as they rely on mutated genes. Using a technique called RNA interference, researchers dialed down the production of thousands of normal proteins to determine which were required for cancer cells to survive. They found that cancer cells growing in a dish rely heavily on many normal proteins to maintain their deviant state. When some of these protein levels drop, cancer cells die, but normal cells often survive. ...> Full Article Cottonseed-based drug shows promise in treating severe brain cancer (5/30/2009)Potent compound overcomes the abnormal growth patterns of glioblastomas ...> Full Article Why some prostate cancer returns (5/29/2009)A study being presented this week at ASCO finds that men with a low oxygen supply to their tumor have a higher chance of the prostate cancer returning, as found by increasing prostate-specific antigen levels following treatment. ...> Full Article Activated stem cells in damaged lungs could be first step toward cancer (5/28/2009)
Study finds dramatic increase in metastatic colon cancer survival (5/28/2009)Better surgical interventions, new chemotherapeutic and biological agents increase 5-year survival from 8 to 30 percent ...> Full Article New model suggests role of low vitamin D in cancer development (5/27/2009)In studying the preventive effects of vitamin D, researchers at the Moores Cancer Center at the University of California, San Diego, have proposed a new model of cancer development that hinges on a loss of cancer cells' ability to stick together. The model, dubbed DINOMIT, differs substantially from the current model of cancer development, which suggests genetic mutations as the earliest driving forces behind cancer. ...> Full Article Is there any association between COX2 and colon cancer? (5/26/2009)A research group from the United States evaluated the association of variations in the cyclooxygenase-2 (COX2) and uridine diphosphate glucuronosyltransferase 1A6 (UGT1A6) genes and non-steroidal anti-inflammatory drugs (NSAIDs) use with risk of colon cancer. They did not observe the association of any variant with risk of colon cancer, nor did they observe that variation in these genes altered the protective effect of NSAIDs. ...> Full Article A novel marker of colorectal carcinoma (5/26/2009)A research group from China determined if TSPAN1 overexpression is associated with clinicopathological and prognostic factors in human colorectal adenocarcinoma. They found the expression of TSPAN1 gene is increased in colorectal carcinoma, suggesting that TSPAN1 might serve as an independent prognostic factor. ...> Full Article Why do people with Down syndrome have less cancer? (5/24/2009)Research in mice and human stem cells suggests new therapeutic targets ...> Full Article New tool helps researchers identify DNA patterns of cancer, genetic disorders (5/21/2009)
Researchers make discovery in colon cancer prevention (5/20/2009)A new study finds that individuals who have low expression of the "Celebrex gene," 15-PGDH, are actually resistant to Celebrex treatment when used to prevent colon cancer. ...> Full Article Quick test for prostate cancer (5/19/2009)A new three-minute test could help in diagnosing prostate cancer, the most common cancer in men in the UK, according to scientists. ...> Full Article Environmental exposures may damage DNA in as few as three days (5/18/2009)Exposure to particulate matter has been recognized as a contributing factor to lung cancer development for some time, but a new study indicates inhalation of certain particulates can actually cause some genes to become reprogrammed, affecting both the development and the outcome of cancers and other diseases. ...> Full Article Genetic marker may predict early onset of prostate cancer (5/18/2009)Fox Chase Cancer Center researchers have identified a genetic marker that is associated with an earlier onset of prostate cancer in Caucasian men who have a family history of prostate cancer. ...> Full Article Long-term study shows low oxygen levels in prostate tumors can predict recurrence (5/18/2009)Fox Chase Cancer Center researchers have discovered that low-oxygen regions in prostate tumors can be used to predict a rise in prostate-specific antigen levels, a marker of tumor recurrence in prostate cancer. ...> Full Article Study points toward relationship between cancer stem cells and prognosis in primary breast cancer (5/16/2009)
A surprise 'spark' for pre-cancerous colon polyps (5/15/2009)Study pinpoints protein in polyp formation: more effective treatments possible ...> Full Article Novel therapy may prove effective in treatment of 30 percent of cancers (5/15/2009)Ground-breaking Canada-wide clinical trial deemed very successful ...> Full Article Study finds iron levels not predictive of survival for form of blood cancer (5/13/2009)Iron-chelating drugs have been heavily promoted for use in patients with primary myelofibrosis, a form of blood cancer often treated with blood transfusion. These drugs, however, which withhold available iron in the body, are highly expensive and potentially toxic. ...> Full Article Worldwide success in treatment of liver tumors (5/13/2009)A Leicester consultant surgeon who has developed a pioneering technique using microwaves to destroy liver tumors has treated more than 100 patients in the UK and other patients are now being treated internationally. ...> Full Article Scientists identify gene in breast cancer pathway (5/13/2009)Findings could guide treatment and lead to new therapies ...> Full Article Genes found to play a role in breast cancer's spread to the brain (5/9/2009)New research led by investigators at Memorial Sloan-Kettering Cancer Center identifies three genes that specifically mediate the metastasis, or spread, of breast cancer to the brain and illuminates the mechanisms by which this spread occurs. The study was published online today in Nature. ...> Full Article Exercise programs may improve symptoms in non-small cell lung cancer patients (5/8/2009)Researchers at Massachusetts General Hospital found that exercise impacts the health and quality of life of patients with an advanced or incurable lung cancer diagnosis. Between October 2004 and August 2007, Dr. Temel and her team enrolled 25 lung cancer patients in a study to evaluate the feasibility, efficacy and safety of a structured, hospital-based exercise program in these patients. ...> Full Article Cancer-causing virus associated with higher risk of new HIV infection (5/7/2009)Infection with anal human papillomavirus, a virus that can cause anal and cervical cancers, is associated with a higher risk of new HIV infection in previously HIV-negative men who have sex with men, according to new UCSF research ...> Full Article Hypothyroidism in women associated with liver cancer (5/6/2009)Women with a history of hypothyroidism face a significantly higher risk of developing liver cancer ...> Full Article Personalized treatment for early lung cancer (5/5/2009)Cancer vaccines and targeted therapies are beginning to offer new treatment options following surgery for patients with early stages of lung cancer, experts said at the first European Multidisciplinary Conference in Thoracic Oncology in Lugano, Switzerland. ...> Full Article Experimental drug shows promise against head and neck cancer (5/4/2009)
Prostate cancer immunotherapy significantly prolongs survival in men with advanced prostate cancer (5/3/2009)Sipuleucel-T (Provenge), an experimental immunotherapy improved survival in men with metastatic disease, according to new results to be presented April 28 at the American Urological Association Annual Scientific Meeting in Chicago. These data from the Phase 3 Immunotherapy for Prostate AdenoCarcinoma Treatment study were presented during the meeting's Late Breaking Science Forum. ...> Full Article Fat droplet nanoparticle delivers tumor suppressor gene to tumor and metastatic cells (5/2/2009)Dr. Esther Chang describes the most recent developments in human trials of the first systemic, nonviral, tumor-targeted, nanoparticle method designed to restore normal gene function to tumor cells while completely bypassing normal tissue April 21 at an American Association of Anatomists scientific session at Experimental Biology 2009 in New Orleans. ...> Full Article Topical cream studied as way to treat skin cancer without the knife (5/1/2009)Saint Louis University researchers find that a topical drug shows promise in treating some types of skin cancer, potentially reducing the area needing surgery, managing the cancer and minimizing its recurrence. ...> Full Article Men treated for localized prostate cancer could benefit from pomegranate juice consumption (4/30/2009)
Upside-down world: DNA protecting protein helps cancer drug to kill cells (4/30/2009)Some DNA repair enzymes can become double-edged swords -- If they work too slowly, they can block necessary cell maintenance and contribute to cell death. This could explain the success of the cancer drug 5-Fluorouracil (5FU) and help clinicians to predict patient's response to chemotherapy. The work, published in this week's issue of PLoS Biology, reports that 5FU keeps the DNA-repair enzyme TDG too busy to perform properly in cancer cells, thereby promoting tumor death. ...> Full Article WA discovery a key to blood cell development (4/30/2009)A West Australian research team has made the world-first discovery a 'pied piper' molecule within blood cells, called Liar, that leads other molecules into the nucleus of the cell, and could offer a key in treating prostate, breast and colon cancers as well as leukemia. ...> Full Article Dietary acrylamide not associated with increased lung cancer risk in men (4/29/2009)Dietary acrylamide was not associated with an increased risk of lung cancer, according to data from a large prospective case-cohort study in the April 28 online issue of the Journal of the National Cancer Institute. ...> Full Article Instead of fighting breast cancer, immune cell promotes its spread (4/27/2009)Researchers at the UC San Diego School of Medicine and the Moores UCSD Cancer Center have new evidence that a type of immune system cell thought to be part of the first line of defense against breast cancer may also help promote its spread. They have found that when these cells, known as lymphocytes, make an inflammatory protein called RANKL (RANK ligand), breast cancer is more likely to spread to the lungs. ...> Full Article Beyond associations: Colorectal cancer culprit found (4/27/2009)Genetics plays a key role in risk for colorectal cancer, the second leading cause of cancer-related deaths in the United States. Several genetic markers are associated with the disease, but finding the biological events that lead to cancer is much more difficult. In a study published online in Genome Research, scientists identified a common genetic variation associated with CRC risk and its functional implications, shedding new light on the basis of this disease. ...> Full Article Vitamin K with sorafenib showed anti-tumor effects in pancreas cancer, hepatocellular carcinoma (4/26/2009)When given with vitamin K, the necessary sorafenib dose was lower, which could help curb a debilitating adverse effect ...> Full Article Hormone therapy offers potential protective effect against colon cancer in older women (4/26/2009)In a large study, a national team of researchers led by Mayo Clinic scientists observed that self-reported use of hormone therapy was associated with a significantly lower colorectal cancer risk. However, the mechanisms for the apparent protective association are still unclear. ...> Full Article Walnuts may prevent breast cancer (4/25/2009)
Charred meat may increase risk of pancreatic cancer (4/25/2009)Meat cooked at high temperatures to the point of burning and charring may increase the risk of pancreatic cancer, according to data presented at the American Association for Cancer Research 100th Annual Meeting 2009. ...> Full Article Natural protein may halt colorectal cancer's spread (4/25/2009)Medical College of Wisconsin Cancer Center researchers in Milwaukee have learned that a protein, CXCL12, that normally controls intestinal cell movement, has the potential to halt colorectal cancer spreading. These studies represent a potential mechanism by which CXL12 may slow cancer spreading. Controlling this process could lead to new biological therapies for colorectal cancers. ...> Full Article Radiation exposure associated with more aggressive thyroid cancer, worse outcomes (4/24/2009)Patients with thyroid cancer who have previously been exposed to radiation -- for example, in the workplace, through environmental exposure or for treatment of acne or another condition -- appear to have more aggressive disease and tend to have worse outcomes in the long term, according to a report in the April issue of Archives of Otolaryngology-Head & Neck Surgery, one of the JAMA/Archives journals. ...> Full Article Human lung tumors destroy anti-cancer hormone vitamin D, researchers find (4/24/2009)Human lung tumors have the ability to eliminate vitamin D, a hormone with anti-cancer activity, a new study from the University of Pittsburgh Cancer Institute suggests. Results of the study, Abstract Number 2402, are being presented at the 100th annual meeting of the American Association for Cancer Research, April 18-22, in Denver. ...> Full Article High levels of PEA-15 shrink breast cancer tumors (4/24/2009)Mouse model findings indicate protein is new, important target for therapy ...> Full Article Researchers formulate treatment combination lethal to pancreatic cancer cells (4/23/2009)A combination of two targeted therapies packs a powerful punch to kill pancreatic cancer cells in the laboratory, Mayo Clinic cancer researchers report. With further testing of these drugs that are from classes of pharmaceuticals already used in patients, the Mayo research may lead to new treatment opportunities for patients with pancreatic cancer, which is extremely difficult to treat. ...> Full Article An herbal extract inhibits the development of pancreatic cancer (4/23/2009)An herb recently found to kill pancreatic cancer cells also appears to inhibit development of pancreatic cancer as a result of its anti-inflammatory properties, according to researchers from the Kimmel Cancer Center at Jefferson. The data were presented at the AACR 100th Annual Meeting 2009 in Denver. ...> Full Article Agent Orange exposure increases veterans' risk of aggressive recurrence of prostate cancer (4/23/2009)
Genetic variations in miRNA processing pathway and binding sites help predict ovarian cancer risk (4/22/2009)
Large study documents how p53 mutations link to high-grade breast cancer, poor outcomes (4/22/2009)In what is believed to be the largest study of its kind in the US, researchers have found that almost 26 percent of women studied who have breast cancer have mutations in a gene important in controlling cell growth and death, and that patients with mutations in this gene -- known as p53 -- had poorer outcomes including a significantly increased risk of death from the cancer. ...> Full Article Newly discovered epidermal growth factor receptor active in human pancreatic cancers (4/22/2009)Finally some promising news about pancreatic cancer, one of the most fatal cancers, due to the difficulties of early detection and the lack of effective therapies: Johns Hopkins University pathologist Akhilesh Pandey has identified an epidermal growth factor receptor aberrantly active in approximately a third of the 250 human pancreatic cancers studied. ...> Full Article Autopsy study links prostate cancer to single rogue cell (4/22/2009)One cell... one initial set of genetic changes -- that's all it takes to begin a series of events that lead to metastatic cancer. Now, Johns Hopkins experts have tracked how the cancer process began in 33 men with prostate cancer who died of the disease. ...> Full Article Veterinary oncologists advance cancer drugs for humans and pets (4/21/2009)As more pet owners are choosing to treat their pets' cancers through advanced medicine, veterinarians gain valuable knowledge about the progression and treatment of cancers in humans through pet trials of new drugs. To help organize nationwide trials in tumor-bearing dogs using cancer drugs, the National Cancer Institute has launched the Comparative Oncology Trials Consortium. Faculty members in the University of Missouri's Scott Endowed Program in Veterinary Oncology participated in COTC's first trial. ...> Full Article Biodegradable gel being studied as a treatment for esophageal cancer (4/21/2009)Nonsurgical therapy for underdiagnosed, rare and deadly disease ...> Full Article Scorpion venom with nanoparticles slows spread of brain cancer (4/20/2009)
Colorectal cancer risks quantified (4/20/2009)Although the presenting features of colorectal cancer are well known, the risks they confer are less well defined. New research published in the open access journal BMC Medicine describes the exact risks posed by eight clinical features for the development of colorectal cancer in a large group of patients. ...> Full Article Experimental insulin-like growth factor receptor inhibitor reduced pancreatic cancer growth (4/17/2009)...> Full Article SIRT1 takes down tumors (4/15/2009)
Scientists identify chemical compound that may stop deadly brain tumors (4/14/2009)Researchers at the University of North Carolina at Chapel Hill School of Medicine have identified a compound that could be modified to treat one of the most deadly types of cancer, and discovered how a particular gene mutation contributes to tumor growth. ...> Full Article Colon cancer shuts down receptor that could shut it down (4/14/2009)
New method for detection of phosphoproteins reveals regulator of melanoma invasion (4/13/2009)Scientists have developed a new approach for surveying phosphorylation, a process that is regulated by critical cell signaling pathways and regulates several key cellular signaling events. The research, published by Cell Press in the April 10 issue of the journal Molecular Cell, describes the regulation of a previously uncharacterized protein and demonstrates that it plays an important role in cancer cell invasion. ...> Full Article Drug shows activity in men with advanced prostate cancer (4/13/2009)A new multi-center study shows that an experimental drug lowers prostate specific antigen levels -- a marker for tumor growth -- in men with advanced prostate cancer for whom traditional treatment options have failed. The study, led by researchers at Memorial Sloan-Kettering Cancer Center, is published today in Science Express, the online version of the journal Science. ...> Full Article Omega-3 fatty acids may benefit cancer patients undergoing major operations (4/12/2009)New research from Trinity College Dublin published in this month's Annals of Surgery points to a potentially significant advance in the treatment of patients undergoing major cancer surgery. ...> Full Article Gene fusion discovery may lead to improved prostate cancer test (4/12/2009)Weill Cornell Medical College study identifies novel type of gene fusion that may be common cancer mechanism ...> Full Article More intense bladder cancer treatment does not improve survival (4/11/2009)Despite enduring more invasive tests and medical procedures, patients who were treated aggressively for early stage bladder cancer had no better survival than patients who were treated less aggressively, according to a new study from researchers at the University of Michigan Comprehensive Cancer Center. ...> Full Article Novel lung cancer vaccine shows promise in fighting early-stage lung cancer (4/11/2009)An experimental vaccine that triggers the patient's immune system to identify and attack specific tumor cells is showing new promise for the treatment of early lung cancer. Thoracic surgeons at Rush University Medical Center are researching the vaccine called MAGE-A3 Antigen-Specific Cancer Immunotherapeutic, which is designed to kill cancer cells without harming normal cells. Rush is one of only five hospitals in Illinois offering the vaccine. ...> Full Article Compendium of pancreatic cancer biomarkers established as strategic approach to early detection (4/11/2009)A cancer scientist from Johns Hopkins has convinced an international group of colleagues to delay their race to find new cancer biomarkers and instead begin a 7,000-hour slog through a compendium of 50,000 scientific articles already published to assemble, decode and analyze the molecules that might herald the furtive presence of pancreatic cancer. ...> Full Article Gene helps protect tumor suppressor in breast cancer (4/10/2009)
Multifocal lung cancers appear to originate from single cancer clone (4/10/2009)Multiple, anatomically distinct lung cancer tumors may frequently arise from a single cancer cell, according to a retrospective analysis of patient tumor samples published in the April 7 online issue of the Journal of the National Cancer Institute. ...> Full Article High-dose radiation improves lung cancer survival, study finds (4/9/2009)Concurrent chemotherapy, radiation also linked to better survival ...> Full Article Researchers discover mechanism of cell type-specific signaling in tumor development (4/9/2009)Mayo Clinic researchers have discovered the mechanisms behind two key checkpoints in cell growth and development -- factors that may ultimately allow investigators to benchmark progression of tumor cells or stop them from further development. The findings appear in the current online issue of Developmental Cell. ...> Full Article How tumor cells move (4/9/2009)Researchers in Heidelberg discover new protein that is suppressed in particularly aggressive cancer cells; article in Nature Cell Biology ...> Full Article Broccoli sprouts may prevent stomach cancer by defeating Helicobacter pylori (4/7/2009)Three-day-old broccoli sprouts, a widely available human food, suppressed Helicobacter pylori infections, according to a report in Cancer Prevention Research, a journal of the American Association for Cancer Research. H. pylori infections are one of the most common bacterial infections worldwide and are a major cause of stomach cancer. ...> Full Article A potential new target for treatment of hormone refractory prostate cancer (4/7/2009)A new study identifies a protein that modifies the androgen receptor and influences its ability to regulate target genes linked with the progression of prostate cancer. The research, published by Cell Press in the April 7 issue of the journal Cancer Cell, may also drive creation of new strategies for the treatment of advanced prostate cancer that no longer responds to traditional anti-hormone therapies. ...> Full Article Genetic link uncovered in disparate colon cancer death (4/5/2009)Disruptive p53 alteration tied to African-American incidence of advanced disease ...> Full Article Researchers find marker for severity in adult brain cancer (4/4/2009)
Increase in p53 mutation linked to advanced colorectal cancer in blacks (4/3/2009)Researchers have identified a possible genetic cause for increased risk for a more advanced form of colorectal cancer in blacks that leads to shorter survival, according to data published in Clinical Cancer Research, a journal of the American Association for Cancer Research. ...> Full Article Researchers identify a protein that may help breast cancer spread, beat cancer drugs (4/2/2009)New research from UC Davis Cancer Center shows that a protein called Muc4 may be the essential ingredient that allows breast cancer to spread to other organs and resist therapeutic treatment. ...> Full Article Grad's work helps diagnose skin cancer without a biopsy (4/2/2009)A recent master's graduate at Montana State University is working on a handheld laser microscope that could reduce the number of biopsies needed to diagnose various types of cancer. ...> Full Article New link in liver cancer (3/31/2009)
Scientists find structure of a protein that makes cancer cells resistant to chemotherapy (3/30/2009)A research team at the Scripps Research Institute has obtained the first glimpse of a protein that keeps certain substances, including many drugs, out of cells. The protein, called P-glycoprotein or P-gp for short, is one of the main reasons cancer cells are resistant to chemotherapy drugs. Understanding its structure may help scientists design more effective drugs. ...> Full Article Scientists reveal mechanism that regulates cancer-causing gene (3/29/2009)Two URI scientists have revealed how a cancer causing protein is regulated by reactive oxygen species -- a type of stress signal. Their findings provide new insight into how this protein normally behaves in human cells and may help in the design of drugs targeting specific cancers. ...> Full Article Scientists fine-tune attack on cancer (3/29/2009)Researchers build computer simulations of laser-nanoparticle treatments ...> Full Article Human papillomavirus genotype distribution in New Mexico cervical cancers (3/28/2009)DNA from human papilloma virus type 16 and HPV type 18 were found in the majority of invasive cervical cancers in New Mexico in the 1980s and 1990s, according to a population-based study published in the March 24 online issue of the Journal of the National Cancer Institute. ...> Full Article Genetic changes outside nuclear DNA suspected to trigger more than half of all cancers (3/27/2009)A buildup of chemical bonds on certain cancer-promoting genes, a process known as hypermethylation, is widely known to render cells cancerous by disrupting biological brakes on runaway growth. Now, Johns Hopkins scientists say the reverse process -- demethylation -- which wipes off those chemical bonds may also trigger more than half of all cancers. ...> Full Article New test may predict spread of breast cancer (3/27/2009)
Omega-3 fatty acids reduce risk of advanced prostate cancer (3/26/2009)Omega-3 fatty acids appear protective against advanced prostate cancer, and this effect may be modified by a genetic variant in the COX-2 gene, according to a report in Clinical Cancer Research, a journal of the American Association for Cancer Research. ...> Full Article Eating soy early in life may reduce breast cancer among Asian women (3/26/2009)Asian-American women who ate higher amounts of soy during childhood had a 58 percent reduced risk of breast cancer, according to a study published in Cancer Epidemiology, Biomarkers and Prevention, a journal of the American Association for Cancer Research. ...> Full Article Ovarian cancers detected early may be less aggressive, questioning effectiveness of screening (3/26/2009)The biology of ovarian cancers discovered at an early stage may render them slower growing and less likely to spread than more aggressive cancers, which typically are discovered in an advanced stage, according to a study led by investigators in the Duke Comprehensive Cancer Center. This finding has implications for the question of whether screening for ovarian cancer could save lives. ...> Full Article Licorice compound offers new cancer prevention strategy (3/25/2009)A chemical component of licorice may offer a new approach to preventing colorectal cancer without the adverse side effects of other preventive therapies, Vanderbilt University Medical Center researchers report. ...> Full Article Vaccine to prevent colon cancer being tested in patients (3/24/2009)Researchers at the University of Pittsburgh School of Medicine have begun testing a vaccine that might be able to prevent colon cancer in people at high risk for developing the disease. If shown to be effective, it might spare patients the risk and inconvenience of repeated invasive surveillance tests, such as colonoscopy, that are now necessary to spot and remove precancerous polyps. ...> Full Article Malnutrition risk underappreciated in laryngeal cancer patients (3/24/2009)Almost half of all patients with cancer of the voice box (larynx) who receive radiotherapy treatment will experience malnutrition, according to new data presented at the European Society for Medical Oncology's Symposium on Cancer and Nutrition. ...> Full Article Researchers identify genetic markers for aggressive head and neck cancer (3/22/2009)Specific microRNA levels may predict poor prognosis ...> Full Article Researchers identify new protein important in breast cancer gene's role in DNA repair (3/21/2009)
A sticky business -- how cancer cells become more 'gloopy' as they die (3/19/2009)The viscosity, or "gloopiness," of different parts of cancer cells increases dramatically when they are blasted with light-activated cancer drugs, according to new images that provide fundamental insights into how cancer cells die, published in Nature Chemistry today, March 15. ...> Full Article Early results favorable for 5-day radiation treatment of early stage prostate cancer (3/18/2009)Preliminary results show that a shortened course of radiation therapy for prostate cancer called stereotactic body radiation therapy provides good PSA response for early stage prostate cancer and has the same side effects as other treatments, according to a March 15 study in the International Journal of Radiation Oncology, Biology, Physics, the official journal of ASTRO. Study authors caution that further follow-up will be necessary to establish that SBRT is as effective in the long term as other proven treatments. ...> Full Article New investigational treatment for bladder cancer, identified with research model (3/17/2009)A new investigational therapy for the treatment of bladder cancer has been identified. The discovery was made using a new research model, using mice, which replicates many aspects of human bladder cancer. The model also enabled the researchers to demonstrate that two major tumor suppressor genes, p53 and PTEN, are inactivated in invasive bladder cancer. The findings and this new model are described in a paper in the March 15, 2009, issue of Genes & Development. ...> Full Article Iron induces death in tumor cells (3/15/2009)Tumor cells and healthy cells differ considerably in metabolism intensity. Scientists of the German Cancer Research Center have taken advantage of this difference; by releasing cellular iron, they were able to induce death selectively in tumor cells. ...> Full Article Study finds folic acid supplements linked to higher risk of prostate cancer (3/15/2009)Men who took daily folic acid supplements had greater than two-fold increased risk of cancer ...> Full Article Genetic differences help protect against cervical cancer (3/15/2009)Women with certain gene variations appear to be protected against cervical cancer, according to a study led by scientists at Albert Einstein College of Medicine of Yeshiva University and reported in Clinical Cancer Research. ...> Full Article Tiny samples could yield big predictive markers for pancreatic cancer (3/14/2009)Researchers believe new biomarkers could help clinicians determine whether a pancreatic cyst is potentially dangerous or not ...> Full Article Fishing for microdeletions that predispose an embryo to develop cancer syndromes in later life (3/14/2009)Researchers have used a common laboratory technique for the first time to detect genetic changes in embryos that could predispose the resulting children to develop certain cancer syndromes. Current preimplantation genetic diagnosis techniques can detect mutations in very small bits of genes or DNA, but, until now, it wasn't easy to detect deletions involving whole genes or long sections of DNA in embryos. The research is published in Human Reproduction journal on Wednesday. ...> Full Article Small molecules block cancer gene (3/13/2009)Finding molecules that block the activity of the oncogene Stat 3 (signal transducer and activator of transcription) required screening literally millions of compounds, using computers that compared the structure of the cancer-causing gene to those of the small molecules, said a Baylor College of Medicine researcher in a report that appears in the current online issue of the journal PLoS ONE. ...> Full Article Study shows microRNA-based diagnostic identifies squamous lung cancer with 96 percent sensitivity (3/12/2009)A new study shows for the first time that a microRNA-based diagnostic test can objectively identify squamous lung cancer with 96 percent sensitivity, according to Harvey Pass, M.D., of the NYU Cancer Institute at NYU Langone Medical Center, one of the authors of the study published online ahead of print in the Journal of Clinical Oncology. ...> Full Article New staging technique might save bladders in some bladder cancer patients (3/11/2009)Pathologists reported encouraging results from a new tumor staging technique that could reduce the need to remove bladders from some patients. ...> Full Article Researchers discover gene mutations that cause childhood brain cancer (3/10/2009)Researchers funded by the Canadian Cancer Society have discovered eight similar genes that, when mutated, appear to be responsible for medulloblastoma -- the most common of childhood brain cancers. ...> Full Article 'Personalized' genome sequencing reveals coding error in gene for inherited pancreatic cancer (3/9/2009)Scientists at the Sol Goldman Pancreatic Cancer Research Center at the Johns Hopkins Kimmel Cancer Center have used "personalized genome" sequencing on an individual with a hereditary form of pancreatic cancer to locate a mutation in a gene called PALB2 that is responsible for initiating the disease. The discovery marks their first use of a genome scanning system to uncover suspect mutations in normal inherited genes. ...> Full Article Optical techniques show continued promise in detecting pancreatic cancer (3/8/2009)Optical technology developed by Northwestern University researchers has been shown to be effective in detecting the presence of pancreatic cancer through analysis of neighboring tissue in the duodenum. The promising new technology uses novel light-scattering techniques to analyze extremely subtle changes in the duodenum's cells. Cells that appear normal using traditional microscopy techniques do show signs of abnormality when examined using the Northwestern technique, which provides cell analysis on the much smaller nanoscale. ...> Full Article Student develops new innovations to selectively kill cancer cells (3/7/2009)
Drinking wine lowers risk of Barrett's esophagus, precursor to nation's fastest growing cancer (3/6/2009)Kaiser Permanente study is first & largest to examine connection between alcohol & Barrett's esophagus ...> Full Article Newly discovered gene plays vital role in cancer (3/5/2009)Gene p53 protects against cancer and is usually described as the most important gene in cancer research. However, scientists at the Swedish medical university Karolinska Institutet have now shown that a previously unknown gene, Wrap53, controls the activity of p53. As the regulation mechanism is relatively unexplored, the study opens up new routes to solving the mystery of cancer. ...> Full Article Liver tumors associated with metabolic syndrome differ from other tumors (3/5/2009)Liver cancer patients whose only risk factor is metabolic syndrome has distinct forms compared to other liver tumors ...> Full Article Proepithelin encourages cell growth and migration in prostate cancer (3/5/2009)Researchers from Thomas Jefferson University have identified a protein that appears to play a significant role in the growth and migration of prostate cancer cells, especially androgen-independent prostate cancer cells. ...> Full Article New findings measure precise impact of fat on cancer spread (3/4/2009)
Researchers ID gene involved in pancreatic cancer (3/3/2009)Researchers from the University of Michigan Comprehensive Cancer Center have identified a gene that is overexpressed in 90 percent of pancreatic cancers, the most deadly type of cancer. ...> Full Article Determining risk for pancreatic cancer (3/1/2009)Experimental technique safely differentiates patients with pancreatic cancer, precursor lesions and benign tumors ...> Full Article Researchers report breakthrough in HPV research (2/28/2009)UAB researchers have developed a new, inexpensive and efficient method for producing and studying a type of human papillomavirus that causes cervical cancer. The process could speed understanding of how the virus functions and causes diseases, and lead to new prevention or treatment options. ...> Full Article Male infertility associated with testicular cancer (2/28/2009)Men who are infertile appear to have an increased risk of developing testicular cancer, according to a report in the Feb. 23 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. ...> Full Article Lowering your cholesterol may decrease your risk of cancer (2/27/2009)Current research suggests that lowering cholesterol may block the growth of prostate tumors. The related report by Solomon et al, "Ezetimibe Is an Inhibitor of Tumor Angiogenesis," appears in the March 2009 issue of the American Journal of Pathology. ...> Full Article Suppressing cancer with a master control gene (2/27/2009)Starting with the tiny fruit fly and then moving into mice and humans, researchers at VIB and K. U. Leuven show that expression of the same gene suppresses cancer in all three organisms. Reciprocally, switching off the gene -- called Ato in flies and ATOH1 in mammals -- leads to cancer. The authors show there is a good chance that the gene can be switched on again with a drug. They report their findings in two papers in the leading online open-access journal PLoS Biology. ...> Full Article Enhanced skin cancer risk linked to defects in cellular aging controls (2/27/2009)Mouse model of a UV sensitivity syndrome illustrates skin stem cell dysfunction is linked to cancer pathology ...> Full Article New 'bubble' targets only cancer cells (2/25/2009)
2 gene mutations linked to most common brain cancers -- and longer survival (2/23/2009)Scientists at the Johns Hopkins Kimmel Cancer Center and Duke University Medical Center have linked mutations in two genes, IDH1 and IDH2, to nearly three-quarters of several of the most common types of brain cancers known as gliomas. Among the findings: people with certain tumors that carry these genetic alterations appear to survive at least twice as long as those without them. ...> Full Article Genetic ID of marker in lymph nodes may be linked to colorectal cancer recurrence risk (2/21/2009)A preliminary report suggests that genetic testing may help identify a marker in lymph nodes that is associated with an increased risk of colorectal cancer recurrence among patients in whom conventional testing indicates that those lymph nodes show no evidence of cancer spread, according to a study in the Feb. 18 issue of JAMA. ...> Full Article Researchers identify gene linked to aggressive progression of liver cancer (2/20/2009)Virginia Commonwealth University researchers have identified a gene that plays a key role in regulating liver cancer progression, a discovery that could one day lead to new targeted therapeutic strategies to fight the highly aggressive disease. ...> Full Article In flurry of studies, researcher details role of apples in inhibiting breast cancer (2/20/2009)Six studies published in the past year by a Cornell researcher add to growing evidence that an apple a day -- as well as daily helpings of other fruits and vegetables -- can help keep the breast-cancer doctor away. ...> Full Article Team develops nano-hydrogels capable of detecting cancer cells (2/20/2009)One of the problems in the treatment of cancers continues to be the lack of ability when it comes to discriminating between healthy and unhealthy cells, with the result being that all cells are affected non-specifically by the treatment. ...> Full Article New lab evidence suggests preventive effect of herbal supplement in prostate cancer (2/18/2009)DHEA is a natural circulating hormone and the body's production of it decreases with age. Men take DHEA as an over-the-counter supplement because it has been suggested that DHEA can reverse aging or have anabolic effects since it can be metabolized in the body to androgens. ...> Full Article Engineers create intelligent molecules that seek-and-destroy diseased cells (2/16/2009)Current treatments for diseases like cancer typically destroy nasty malignant cells, while also hammering the healthy ones. Using new advances in synthetic biology, researchers are designing molecules intelligent enough to recognize diseased cells, leaving the healthy cells alone. "We basically design molecules that actually go into the cell and do an analysis of the cellular state before delivering the therapeutic punch," said Christina Smolke, assistant professor of bioengineering who joined Stanford University in January. ...> Full Article Nanoscopic changes to pancreatic cells reveal cancer (2/16/2009)New spectroscopy technique may help detect deadly disease early ...> Full Article Researchers find new biomarker for fatal prostate cancer (2/16/2009)New research findings out of Wake Forest University School of Medicine and the University of Wisconsin may help provide some direction for men diagnosed with prostate cancer about whether their cancer is likely to be life-threatening. ...> Full Article People who exercise lower their risk of colon cancer (2/15/2009)An ambitious new study has added considerable weight to the claim that exercise can lower the risk for colon cancer. Researchers at Washington University School of Medicine in St. Louis and Harvard University combined and analyzed several decades worth of data from past studies on how exercise affects colon cancer risk. They found that people who exercised the most were 24 percent less likely to develop the disease than those who exercised the least. ...> Full Article Nanoparticle 'smart bomb' targets drug delivery to cancer cells (2/14/2009)Researchers at North Carolina State University have successfully modified a common plant virus to deliver drugs only to specific cells inside the human body, without affecting surrounding tissue. These tiny "smart bombs" -- each one thousands of times smaller than the width of a human hair -- could lead to more effective chemotherapy treatments with greatly reduced, or even eliminated, side effects. ...> Full Article Researchers discover metabolite linked to aggressive prostate cancer (2/12/2009)Finding could lead to test to help guide treatment decisions ...> Full Article Camouflaging of viral DNA could be crucial step in progression of cancers (2/12/2009)15 percent of cancers can be linked to a viral infection. However, the biological changes that cause some asymptomatic carriers of a virus to develop malignancies are not well understood. In a study published online in Genome Research, scientists mapped a chemical modification of DNA in Epstein-Barr, human papilloma and hepatitis B viruses and found that the viral genomes undergo changes during the progression of disease, with implications for new prevention, diagnosis and treatment strategies. ...> Full Article Marijuana use linked to increased risk of testicular cancer (2/10/2009)Risk appears to be elevated particularly among frequent and/or long-term users ...> Full Article Source of cancer stem cells' resistance to radiation discovered at Stanford (2/8/2009)Much to the dismay of patients and physicians, cancer stem cells -- tiny powerhouses that generate and maintain tumor growth in many types of cancers -- are relatively resistant to the ionizing radiation often used as therapy for these conditions. ...> Full Article Scientists develop crystal ball for personalized cancer treatment (2/7/2009)New tool predicts how a chemotherapy drug will work on individual tumor ...> Full Article Gene expression signature associated with survival in advanced ovarian cancer (2/7/2009)A new study published this week in the open-access journal PLoS Medicine identifies molecular pathways associated with outcomes in ovarian cancer. Currently, outcomes following diagnosis of ovarian cancer are very poor, with up to 65-70 percent of women dying within five years of diagnosis. ...> Full Article Inflammation in colon may get doused before fueling cancer development (2/7/2009)Repeated inflammation that leads to colon cancer may have met its match. A tiny molecule, quercetin, found in most plant-based foods douses the flames before damaging lesions can form in the colon, says Dr. Nancy Turner, Texas AgriLife Research scientist. And the nice thing is that quercetin is readily available in common plant-based foods. So it's not an unachievable goal for us good ol' Americans if we do the right thing with our food consumption. ...> Full Article Stroma genomic signature predicts resistance to anthracyclin-based chemotherapy in breast cancer (2/6/2009)1 step closer to personalized medicine ...> Full Article Gene mutations increase risk for aggressive prostate cancer (2/6/2009)
Rare skin tumor responds better to treatment than melanoma (2/6/2009)A team of Vanderbilt University Medical Center investigators has developed a group of chemical compounds -- the first selective inhibitors of the protein phospholipase D -- that could represent a new class of drugs for treating cancer.The new inhibitors, reported in the February issue of Nature Chemical Biology, block the invasive migration of breast cancer cells, supporting their further development as antimetastatic agents. ...> Full Article Dry beans inhibit development of mammary cancer (2/6/2009)With increasing interest in the ways certain food can reduce people's risks for contracting chronic diseases, a new study demonstrates the benefits of dry beans in reducing the risk of contracting mammary cancer, due to their levels of antioxidants and other cancer reducing contents. ...> Full Article Compounds could be new class of cancer drugs (2/5/2009)A team of Vanderbilt University Medical Center investigators has developed a group of chemical compounds -- the first selective inhibitors of the protein phospholipase D -- that could represent a new class of drugs for treating cancer.The new inhibitors, reported in the February issue of Nature Chemical Biology, block the invasive migration of breast cancer cells, supporting their further development as antimetastatic agents. ...> Full Article Inflammation directly linked to colon cancer (2/5/2009)While chronic inflammation is believed to be a predisposing factor for colon cancer, exact mechanisms linking these conditions remain elusive. Scientists at the Melbourne Branch of the international Ludwig Institute for Cancer Research and the Technical University Munich have jointly discovered a new piece of this puzzle by demonstrating how the Stat3 protein links inflammation to tumor development, a discovery that may well lead to the identification of new therapeutic targets for colon cancer. ...> Full Article Researchers disrupt biochemical system involved in cancer, degenerative disease (2/4/2009)
Stress may hasten the growth of melanoma tumors (2/3/2009)But common beta-blocker medications might slow that progress ...> Full Article Worm provides clues about preventing damage caused by low-oxygen during stroke, heart attack (2/3/2009)Neurobiologists at Washington University School of Medicine in St. Louis have identified pathways that allow microscopic worms to survive in a low-oxygen, or hypoxic, environment. They believe the finding could have implications for conditions such as stroke, heart attack and cancer. Sensitivity to low oxygen helps determine how damaging those medical conditions can be. ...> Full Article New research findings may enable earlier diagnosis of uterine cancer (2/3/2009)Cancer of the uterus (womb) is the most common gynecological malignancy in the West. Research carried out at the University of Gothenburg, Sweden, has now identified a gene that may simplify future diagnosis. ...> Full Article Skin color studies on tadpoles lead to cancer advance (2/2/2009)The humble tadpole could provide the key to developing effective anti-skin cancer drugs, thanks to a groundbreaking discovery by researchers at the University of East Anglia. ...> Full Article Sequential and alternating chemotherapy and radiation equally effective in larynx cancer therapy (2/2/2009)Larynx cancer patients treated with alternating cycles of chemotherapy and radiation have similar outcomes to patients treated with chemotherapy followed by radiation, according to data from a randomized controlled trial in the Jan. 27 online issue of the Journal of the National Cancer Institute. ...> Full Article Scientists discover how cancer cells survive a chemotherapy drug (1/31/2009)New techniques enabled Weizmann Institute scientists to assess the actions of thousands of proteins in cancer cells and identify those that help some survive a chemotherapy treatment. ...> Full Article Physics, math provide clues to unraveling cancer (1/31/2009)U-M researchers use mathematical modeling to bring new understanding to cancer biology ...> Full Article HPV18 DNA levels are not prognostic for precancerous cervical lesions (1/28/2009)Perhaps surprisingly, the number of copies of the carcinogenic human papillomavirus type 18 (HPV18) relative to cellular DNA is not associated with the likelihood of progression to advanced precancerous lesions of the cervix, according to a study in the Jan. 27 online issue of the Journal of the National Cancer Institute. ...> Full Article Frequent sex and masturbation in 20s and 30s linked to higher prostate cancer risk (1/27/2009)But study also shows that risks diminish with age, particularly in a man's 50s ...> Full Article How chemotherapy drugs block blood vessel growth, slow cancer spread (1/27/2009)Researchers at the Johns Hopkins University School of Medicine have discovered how a whole class of commonly used chemotherapy drugs can block cancer growth. Their findings, reported online this week at the Proceedings of the National Academy of Sciences Early Edition, suggest that a subgroup of cancer patients might particularly benefit from these drugs. ...> Full Article Cancer-causing gene discovery suggests new therapies (1/26/2009)Scientists have discovered a novel way by which a much-studied cancer-promoting gene accelerates the disease. The finding suggests a new strategy to halt cancer's progress. ...> Full Article Study links smoking with most male cancer deaths (1/25/2009)The association between tobacco smoke and cancer deaths -- beyond lung cancer deaths -- has been strengthened by a recent study from a UC Davis researcher, suggesting that increased tobacco control efforts could save more lives than previously estimated. ...> Full Article Measles virus may be effective prostate cancer treatment (1/24/2009)Measles virus vaccine derivatives may prove to be an effective treatment for patients with advanced prostate cancer ...> Full Article Mayo Clinic researchers find experimental therapy turns on tumor suppressor gene in cancer cells (1/24/2009)Researchers at Mayo Clinic have found that the experimental drug they are testing to treat a deadly form of thyroid cancer turns on a powerful tumor suppressor capable of halting cell growth. Few other cancer drugs have this property, they say. ...> Full Article Inflammation contributes to colon cancer (1/24/2009)Researchers led by Drs. Lillian Maggio-Price and Brian Iritani at the University of Washington found that mice that lack the immune inhibitory molecule Smad3 are acutely sensitive to both bacterially-induced inflammation and cancer. They report these findings in the January 2009 issue of the American Journal of Pathology. ...> Full Article Researchers work out structure of TIGAR, a possible cancer flag (1/23/2009)
Study of human tissue reveals potential colon cancer biomarker (1/22/2009)University of Cincinnati scientists have identified a new biomarker that could help predict a person's risk of developing colon cancer and how aggressive it may become. ...> Full Article Dartmouth researchers identify potential cancer target (1/21/2009)Dartmouth Medical School researchers have found two proteins that work in concert to ensure |
