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All Articles Tagged As: cancer
Stem cell indicator should boost bowel cancer survival rates (8/27/2008)Scientists have developed a more accurate way of identifying aggressive forms of bowel cancer, which should improve both treatment and survival. ...> Full Article Keeping cells youthful: How telomere-building proteins get drawn into the fold (8/27/2008)It may take just one or two proteins to polish off a simple cellular task, but life-or-death matters, such as caring for the ends of chromosomes known as telomeres, require interacting crews of proteins, all with a common goal but each with a specialized task. ...> Full Article Anti-Cancer Flower Power (8/27/2008)Researchers are combating cancer with a jasmine-based drug ...> Full Article Normalizing tumor vessels to improve cancer therapy (8/26/2008)Researchers explore why tumor blood vessels are abnormal and leaky ...> Full Article Scientists identify new drug target against virulent type of breast cancer (8/26/2008)The enzyme target, Brk, is shown to be an accelerator of HER2-positive tumors ...> Full Article Researchers study how cancer cells come unstuck (8/25/2008)Scientists have started a three year study into the junctions that hold cells together, giving insight into how cancer cells can break off and spread to other parts of the body. ...> Full Article Dense tissue promotes aggressive cancers (8/24/2008)New research may explain why breast cancer tends to be more aggressive in women with denser breast tissue. ...> Full Article Going from ulcers to cancer (8/23/2008)Researchers have uncovered a big clue as to why some of the bacteria that cause stomach ulcers pose a greater risk for serious problems like stomach cancer than others ...> Full Article Why a common treatment for prostate cancer ultimately fails (8/23/2008)Hair on a man's head offers clues about versatility of molecule central to disease ...> Full Article Synthetic Molecules Could Add Spice To Fight Against Cancer (8/21/2008)Researchers are combining organic chemistry, computer-aided design and molecular biology techniques in developing and testing pharmaceutical compounds that can fight breast and prostate cancer cells. ...> Full Article Researchers develop model to find blood biomarkers that estimate tumor size (8/21/2008)Researchers have begun to map out a way to correlate the levels of so-called blood biomarkers with cancer volume. The effort will guide the development of new tests to facilitate early detection of the disease. ...> Full Article New imaging technique could catch cancer early (8/20/2008)Nanotechnology is the key to a new, noninvasive biomedical imaging technique that could detect early stages of cancer. The method holds promise for determining not just where tumors are located but also for monitoring their treatment, said scientists at the Stanford University School of Medicine who demonstrated the new approach in mice. ...> Full Article By amplifying cell death signals, scientists make precancerous cells self-destruct (8/18/2008)Scientists have figured out a way in mice to amplify the signals that tell precancerous cells to die. The trick: Inactivating a protein that normally helps cells to avoid self-destruction. ...> Full Article Vaccine Strategy Shows Promise in Prostate Cancer Patients (8/18/2008)New research indicates that giving patients a continuous low dose of an immune system booster, a method known as metronomic dosing, as part of a therapeutic prostate cancer vaccine strategy is safe and produces similar immune responses and fewer side effects than the more common dosing method, which is not well tolerated by many patients. ...> Full Article Cancer signatures uncovered (8/17/2008)A new systematic analysis of the relationship between the neoplastic and developmental transcriptome provides an outline of trends in cancer gene expression. ...> Full Article Therapeutic target ID'd for deadly childhood muscle cancer (8/16/2008)Curbing the activity of a substance called 'platelet-derived growth factor receptor A' dramatically reduced aggressiveness of an often-untreatable childhood muscle cancer in mice and cells ...> Full Article Scientists discover major genetic cause of colorectal cancer (8/15/2008)Hikes risk of developing cancer to 50 percent ...> Full Article Experimental chemotherapy regimen shows promise in treating advanced lung cancer (8/14/2008)A combination of chemotherapy agents that have been tested in other tumor types appears to be a promising alternative to standard treatment for advanced non-small cell lung cancer ...> Full Article Scientists use old enemy to K.O. cancer (8/14/2008)Chemists are pulling cancer onto a sucker punch by getting infected cells to drop their guard ...> Full Article Key to treating cancer may be finding its original cell (8/13/2008)Cancer biologists are turning their attention to the normal cells that give rise to cancers, to learn more about how tumor growth might be stopped at the earliest opportunity. ...> Full Article Researchers uncover cancer survival secrets (8/12/2008)A team of Monash University researchers has uncovered the role of a family of enzymes in the mutation of benign or less aggressive tumours into more aggressive, potentially fatal, cancers in the human body. ...> Full Article Research team unravels new cellular repair mechanism (8/10/2008)Work in yeast cells could lead to similar discovery in humans and new cancer treatments ...> Full Article Researchers unveil vital key to cancer (8/9/2008)scientists have uncovered the 3D structure of Mps1 - a protein that regulates the number of chromosomes during cell division and thus has an essential role in the prevention of cancer - which will lead to the design of safer and more effective therapies. ...> Full Article First step towards switching off breast cancer and leukaemia (8/9/2008)scientists have identified a way to 'switch off' a molecule, a key player in the molecular processes that trigger breast cancer and certain forms of leukemia. ...> Full Article Researchers find cancer-inhibiting compound under the sea (8/8/2008)Researchers have discovered a marine compound off the coast of Key Largo that inhibits cancer cell growth in laboratory tests, a finding they hope will fuel the development of new drugs to better battle the disease. ...> Full Article Researchers Discover How Tumor Suppressor Inhibits Cell Growth (8/8/2008)Genes that inhibit the spontaneous development of cancer are called tumor suppressor genes. One of the major tumor suppressors is p53, a protein that acts in the cell nucleus to control the expression of other genes whose products can inhibit cell proliferation (increase in cell number) and cell growth (increase in cell size). Abnormal cell proliferation and growth are characteristics of cancer. Scientists previously knew which p53 target genes inhibit cell proliferation, but those required for inhibition of cell growth were unknown. ...> Full Article Alternate genes linked to breast, thyroid and kidney cancer predisposition (8/8/2008)A new discovery may lead to more effective screening and treatment for patients with a difficult to recognize syndrome characterized by tumor-like growths and a high risk of developing specific cancers ...> Full Article Researchers Publish Findings of a New Chemoprevention Gene Therapy That Kills Pancreatic Cancer Cells (8/6/2008)Chemoprevention gene therapy may prevent and treat pancreatic cancer, one of the most lethal and treatment-resistant forms of cancer ...> Full Article Exposure to Agent Orange linked to prostate cancer in Vietnam veterans (8/6/2008)Vietnam War veterans exposed to Agent Orange have greatly increased risks of prostate cancer and even greater risks of getting the most aggressive form of the disease as compared to those who were not exposed. ...> Full Article Unravelling breast cancer susceptibility (8/3/2008)Scientists are investigating a vital link between radiation sensitivity and breast cancer susceptibility. ...> Full Article New treatment for advanced prostate cancer (8/2/2008)Researchers have developed a novel approach to treating advanced prostate cancer that could be more effective with fewer side effects. ...> Full Article Prostate Cancer Patients Undergoing Hormone Therapy May Experience Cognitive Effects (7/30/2008)Hormone deprivation therapy, a commonly used treatment for prostate cancer, may have subtle adverse effects on cognition in patients--such as in the ability to recall and concentrate ...> Full Article Researchers Unravel Key Mechanism of Cellular Damage in Aging and Disease (7/28/2008)Researchers have taken a first snapshot of how a class of highly reactive molecules inflicts cellular damage as part of aging, heart disease, stroke, cancer, diabetes, kidney disease and Alzheimer's disease to name a few. ...> Full Article Gene suppresses DNA break-induced chromosome errors (7/28/2008)Researchers describe the molecular basis of chromosome translocations, the cause of many childhood diseases ...> Full Article Plasma DNA level is a reliable marker of recurrent esophageal cancer, study finds (7/27/2008)Elevated plasma DNA levels occur prior to clinical evidence of recurrence in majority of patients ...> Full Article Has Cancer Spread? Research Identifies Best Way to Find Answers (7/26/2008)Streamlined Care Will Speed up Diagnosis and Treatment, May Save Lives ...> Full Article Once Suspect Protein Found to Promote DNA Repair, Prevent Cancer (7/25/2008)Scientists caution against targeting HMGB1 to treat other disease ...> Full Article Researchers offer glimpse of rare mutant cells (7/23/2008)Imaging system may help understand origins of cancer ...> Full Article Plants make vaccine for treating type of cancer (7/23/2008)Plants could act as safe, speedy factories for growing antibodies for personalized treatments against a common form of cancer ...> Full Article New breast cancer test under study (7/23/2008)20 centers studying new technology developed by Z-Tech Inc ...> Full Article Checking more lymph nodes linked to cancer patient survival (7/23/2008)May explain why patients at cancer centers and high-volume hospitals live longer ...> Full Article 'Smothered' genes combine with mutations to yield poor outcome in cancer patients (7/21/2008)Researchers have identified a set of genes in breast and colon cancers with a deadly combination of traditional mutations and "smothered" gene activity that may result in poor outcomes for patients. ...> Full Article Scientists Correlate Enzyme Expression Levels (7/20/2008)A method that could be applied widely to explore genetic basis of cancer drug resistance ...> Full Article New Approach to Cancer: Find Most Tightly Controlled Genes (7/19/2008)Scientists have found a new way to study cancer that could be very useful for developing targeted therapies against cancer and possibly many other diseases. ...> Full Article TG2 identified as potential therapeutic target in chemo-resistant ovarian cancer (7/19/2008)Team silences protein with siRNA, implicates TG2 in fourth cancer ...> Full Article How cells die determines whether immune system mounts response (7/18/2008)Finding could have important implications in the treatment of autoimmune diseases and cancer. ...> Full Article New Technique Gets to the Root of Cancer (7/17/2008)Scientists have developed a new method for reconstructing a cell's 'family tree,' and have applied this technique to trace the history of the development of cancer. ...> Full Article Mitochondrial cholesterol makes response to chemotherapy difficult in hepatic cancer (7/16/2008)The mitochondrion is an essential organelle for cell metabolism and for the organisation of the molecular mechanism responsible for cell death. IIBB-CSIC-IDIBAPS researchers have demonstrated that the increase of cholesterol concentration in the mitochondrial membrane makes the action of chemotherapy difficult in cellular hepatocarcinoma. According to these results, drugs such as statins could sensitise cancer cells against chemotherapy since they diminish the level of mitochondrial cholesterol. ...> Full Article TG2 Identified as Potential Target in Chemo-Resistant Ovarian Cancer (7/16/2008)Team silences protein with siRNA, implicates TG2 in fourth cancer ...> Full Article Insect warning colors aid cancer and tropical disease drug discovery (7/15/2008)
Cancer therapies from the ocean? (7/14/2008)Scientists have studied the properties of natural products derived from animals found in Fijian waters, and shown that not only may certain compounds have potential use in anti-cancer therapies, but others may also be useful for improving drug delivery ...> Full Article Bacterial peptide provides new insight into common tumor suppressor (7/14/2008)Scientists have identified a new antitumor drug that might prove useful in developing treatments for a multiple human cancers ...> Full Article Prostate cancer vaccines more effective with hormone therapy (7/14/2008)Among patients with castration-resistant prostate cancer, the addition of hormone therapy following vaccine treatment improved overall survival compared with either treatment alone or when the vaccine followed hormone treatment ...> Full Article Single-nucleotide polymorphisms do not substantially improve risk prediction for breast cancer (7/13/2008)Recently identified genetic markers, called single nucleotide polymorphisms, that are associated with a small but statistically significant increase in the risk of breast cancer do not appear to substantially improve the accuracy of existing models that use clinical factors to predict an individual's risk ...> Full Article Researchers discover mechanism that explains how cancer enzyme winds up on ends of chromosomes (7/13/2008)have shown a mechanism that explains how two essential components of human telomerase-normally active only in early prenatal development but turned back on during cancer growth-are "recruited" from distinct sites in the cell to the telomere, an area at the end of a chromosome that normally protects it from destruction. ...> Full Article Coping with 'chemo brain' (7/12/2008)Study to look at effects of chemotherapy on brain function of breast cancer survivors ...> Full Article Researchers Identify Cancer Preventive Properties in Common Dietary Supplement (7/12/2008)Early laboratory research has shown that resveratrol, a common dietary supplement, suppresses the abnormal cell formation that leads to most types of breast cancer ...> Full Article Herceptin targets breast cancer stem cells (7/12/2008)HER2 gene causes cancer stem cells to multiply, spread ...> Full Article Researchers locate and image prostate cancer as it spreads to lymph nodes (7/12/2008)Discovery may lead to more effective diagnostic and therapeutics ...> Full Article Can recycling be used to treat cancer? (7/11/2008)New research suggests that the cellular recycling might be useful for battling cancer ...> Full Article Protein thought to promote cancer instead functions as a tumor suppressor, researchers report (7/10/2008)A protein previously thought to promote colorectal cancer instead suppresses the growth of human cancer cells in culture ...> Full Article Researchers find molecule that kills kidney cancer cells (7/9/2008)Kidney cancer patients generally have one option for beating their disease: surgery to remove the organ. ...> Full Article Treatment delays result in poor outcomes for men with breast cancer (7/8/2008)Men who develop breast cancer are often not treated until the disease has spread to the point that treatment becomes difficult ...> Full Article Overweight, insulin resistant women at greater risk of advanced breast cancer diagnosis (7/8/2008)Women who have risk factors commonly associated with Type 2 diabetes also have much greater odds of being diagnosed with an advanced breast cancer ...> Full Article Counting tumor cells in blood predicts treatment benefit in prostate cancer (7/8/2008)Counting the number of tumor cells circulating in the bloodstream of patients with castration-resistant prostate cancer can accurately predict how well they are responding to treatment ...> Full Article Researcher using computers to hone cancer-fighting strategies (7/6/2008)Computational technique to evaluate a new class of cancer-killing drugs is attracting worldwide attention from other researchers ...> Full Article Cancer cells revert to normal at specific signal threshold, researchers find (7/5/2008)Cancer starts when key cellular signals run amok, driving uncontrolled cell growth. But scientists report that lowering levels of one cancer signal under a specific threshold reverses this process in mice, returning tumor cells to their normal, healthy state. The finding could help target cancer chemotherapy to tumors while minimizing side effects for the body's healthy cells. ...> Full Article Yeast-Based Vaccine Reduces Tumor Size (7/2/2008)Scientists have found that vaccination with a heat-killed, nontoxic yeast that is genetically engineered to manufacture a common tumor protein can induce specific and repeated anti-tumor immune responses in mice. Vaccination extends overall survival and reduces tumor size in mice that have been injected with cancer cells displaying the same protein that was engineered into the yeast. ...> Full Article Blue light used to harden tooth fillings stunts tumor growth (6/30/2008)A blue curing light used to harden dental fillings also may stunt tumor growth ...> Full Article Pregnancy May Help Protect Against Bladder Cancer (6/30/2008)Pregnancy seems to confer some protection against bladder cancer in mice, scientists have found. ...> Full Article Faulty DNA Repair could be a Risk Factor for Lung Cancer in Nonsmokers (6/30/2008)Faulty DNA Repair could be a Risk Factor for Lung Cancer in Nonsmokers ...> Full Article Researchers identify promising cancer drug target in prostate tumors (6/30/2008)Scientists have blocked the development of prostate tumors in cancer-prone mice by knocking out a molecular unit they describe as a "powerhouse" that drives runaway cell growth. ...> Full Article Higher Coffee Consumption Associated with Lower Liver Cancer Risk (6/29/2008)Liver Cancer is the Third Most Common Global Cause of Cancer Death ...> Full Article New Research On Mutation In Yeast Can Enhance Understanding Of Human Diseases (6/28/2008)Yeast, a model organism heavily relied upon for studying basic biological processes as they relate to human health, mutates in a distinctly different pattern than other model organisms, a finding that brings researchers closer to understanding the role of evolutionary genetics in human diseases and cancer. ...> Full Article Genetic profiling for breast cancer on the horizon (6/28/2008)Scientists have shown it may soon be possible to offer women a genetic test to assess their risk of breast cancer which could aid early diagnosis for those at high risk of the disease. ...> Full Article Marine organisms could hold the secret to reducing cancer (6/27/2008)Research into why a tea derived from an ancient crop from the western Pacific could be responsible for reducing the risk of cancer ...> Full Article Researchers overcome chemotherapy resistance in the lab (6/27/2008)Re-purposed Malaysian folk medication reduces resistance to cancer treatments ...> Full Article Models help scientists understand brain cancer (6/27/2008)Transplanting brain cancer cells directly into similar tissues of immune-deficient mice created a model for the disease that preserved the brain tumor stem cells from which the cancers derived ...> Full Article Common Laser Surgery Used In Uncommon Cancer (6/26/2008)During a routine eye exam earlier this year, Mike Samogala learned he had a rare form of cancer known as melanoma of the eye. Because the cancer was so advanced, surgeons had to remove his eye to save his life. ...> Full Article Laser Surgery Probe Targets Individual Cancer Cells (6/26/2008)Mechanical engineering has developed a laser "microscalpel" that destroys a single cell while leaving nearby cells intact, which could improve the precision of surgeries for cancer, epilepsy and other diseases. ...> Full Article New Cancer Treatment Targets Both Tumor Cells and Blood Vessels (6/25/2008)researchers develop non-toxic treatment that has broad anti-cancer potential ...> Full Article Blocking Protein Proves Toxic to Myeloma Cells (6/25/2008)Researchers have found that cells from a blood-borne cancer called multiple myeloma rely on the activity of a single protein, IRF4, for the activation of a wide range of genes responsible for cell survival and spread. Blocking the production of this protein can be strikingly effective in eliminating cancer cells in laboratory models of multiple myeloma. ...> Full Article Team discovers new inhibitors of estrogen-dependent breast cancer cells (6/24/2008)Researchers have discovered a new family of agents that inhibit the growth of estrogen-dependent breast cancer cells. ...> Full Article New therapy shows promise for fighting treatment-resistant cancer cells (6/24/2008)There is a real possibility for treating the most challenging cancer cases ...> Full Article Scientists find 5 genes involved in the metastasis of breast tumours to the lung (6/24/2008)According to the results of this study, of the five genes identified, the Tenascina-C gene seems to be a good therapeutic target for the treatment of metastatic breast cancer. ...> Full Article Improving understanding of cell behaviour in breast cancer (6/23/2008)Researchers are combining a number of approaches in a dynamic effort to improve our understanding of cell behaviour in breast cancer ...> Full Article Patient's own infection-fighting T cells put late-stage melanoma into long-term remission - without chemotherapy or radiation (6/23/2008)Case is first to show safety and effectiveness of using cloned cells alone to kill tumors ...> Full Article Computer predicts anti-cancer molecules (6/23/2008)New computer-based method of analyzing cellular activity has correctly predicted the anti-tumour activity of several molecules ...> Full Article Modulated radiotherapy can cut treatment time for cancer of the rectum without increasing toxicity (6/21/2008)Application of modulated radiotherapy in the treatment of bowel cancer can enhance the results obtained by means of other conventional therapies. ...> Full Article PET/CT scan could be valuable noninvasive tool for determining stages of ovarian cancer (6/20/2008)Safer alternative could reduce number of unnecessary surgeries ...> Full Article Mutant Mouse Mimics Human Bone Cancer (6/19/2008)Researchers have developed a mouse model of osteosarcoma, the most common form of bone cancer ...> Full Article Urologists identify seven biomarkers that may help pinpoint prostate cancer recurrence (6/18/2008)A simple blood test may help doctors better predict whether prostate cancer will recur or spread in patients who have undergone surgery for the disease ...> Full Article Experimental anti-cancer synthetic molecule targets tumor cell growth and angiogenesis (6/18/2008)A recent study describes a new candidate anti-cancer drug, named HB-19 ...> Full Article New possibilities for breast cancer treatment on the horizon (6/17/2008)Custom-built breast PET/CT scanner could advance breast cancer treatment, ...> Full Article New study shows potential to treat or prevent viral cancers (6/17/2008)Targeting viral antigens offers a novel option to treat-or even prevent- many viral cancers by targeting cancer cells expressing viral antigens or infected cells before they convert into malignancy ...> Full Article CT Lung Cancer Screening No Cure-All for Smokers (6/16/2008)Screening for lung cancer with computed tomography (CT) may help reduce lung cancer deaths in current and former smokers, but it won't protect them from other causes of death associated with smoking ...> Full Article Scientists Discover How Cells Move a Critical Protein (6/16/2008)Researchers have found the pathway through which a signaling protein called Smoothened (Smo) can move into the primary cilium, a discovery that could eventually translate into therapeutic treatments for cancer. ...> Full Article Study Finds Benefits to Earlier Colon Cancer Screenings (6/15/2008)Patients would benefit by having colon cancer screenings earlier than currently recommended ...> Full Article Avoiding Infections Helps Keep Cancer Patients Healthy (6/15/2008)Infections are a major cause of illness and death in cancer patients, but simple steps and common sense can help keep patients healthy and improve their chances of a good recovery. ...> Full Article Remembering 'ABCs' Could Help Identify Skin Cancer Warning Signs (6/15/2008)Recognizing precancerous moles could be as easy as remembering your ABCs. ...> Full Article 'Addicted' cells provide early cancer diagnosis (6/14/2008)Researchers have detected subtle changes that may make the bowel more vulnerable to the development of tumours. ...> Full Article Raloxifene reduces risk of invasive estrogen-receptor positive breast cancer (6/14/2008)Women who took raloxifene were less likely to develop invasive estrogen-receptor (ER) positive breast cancer compared with women who did not ...> Full Article Enhanced Chickens, Eggs, May Prevent Breast Cancer (6/14/2008)Researchers are studying whether adding a component of cotton plants to chicken feed might result in anti-cancer eggs and chicken meat. ...> Full Article Cancer incidence and mortality in young people decreases with increasing deprivation (6/13/2008)Results of research into the associations between cancer and socio-economic deprivation and affluence have shown that, in contrast to cancers in older people, the numbers of new cases and deaths from the disease in teenagers and young adults (TYAs) decrease with increasing deprivation ...> Full Article Anti-estrogen Drug Therapy Reduces Risk of Invasive Breast Cancer in Older Women (6/13/2008)New analysis of a drug approved for osteoporosis prevention and treatment has provided definitive evidence that the medication is also effective as a breast cancer preventative for certain cancers. ...> Full Article Solid Tumor Cells Not Killed by Radiation and Chemotherapy Become Stronger (6/10/2008)Because of the way solid tumors adapt the body's machinery to bring themselves more oxygen, chemotherapy and radiation may actually make these tumors stronger. ...> Full Article Researchers discover traits of aggressive form of prostate cancer (6/10/2008)Prostate cancer linked with SPINK1 gene occurs in 10 percent of cases ...> Full Article Microenvironment a main driver of aggressive multi-lineage leukemia disease type (6/10/2008)Study yields clues into different leukemia forms and possible therapeutic targets ...> Full Article Outing the outliers: Strategy matches oncogene with subtype of prostate cancer (6/10/2008)A new study reveals a previously unidentified candidate oncogene that appears to play a significant role in a subset of prostate cancers. ...> Full Article Synthetic molecules hold promise for new family of anti-cancer drugs (6/7/2008)Synthetic molecules designed by two Hebrew University of Jerusalem researchers have succeeded in reducing and even eliminating the growth of human malignant tissues in mice, while having no toxic effects on normal tissue. ...> Full Article For Patients With Colon Cancer, Family History Of Colorectal Cancer Associated With Reduced Risk Of Recurrence And Death (6/5/2008)Among patients with advanced colon cancer receiving treatment that includes chemotherapy, a family history of colorectal cancer is associated with a significant reduction in cancer recurrence and death, with the risk reduced further by having an increasing number of affected first-degree relatives ...> Full Article Vaccine May Double Survival in Patients with Deadly Brain Tumors (6/4/2008)A vaccine aimed at inducing immunity to the most common and deadly type of brain tumor may stave off recurrence and more than double survival in patients ...> Full Article Gender, Colorectal Cancer Survival Linked (6/3/2008)Findings call for further study into the role of hormonal status in survival, USC researchers say. ...> Full Article How advanced prostate cancer becomes resistant to androgen-deprivation therapy (6/3/2008)Findings suggest androgen production occurs within metastatic prostate tumors ...> Full Article Scientists confirm link between inflammation, cancer (6/3/2008)Chronic inflammation of the intestine or stomach can damage DNA, increasing the risk of cancer ...> Full Article Metformin Increases Pathologic Complete Response Rates in Breast Cancer Patients With Diabetes (6/3/2008)First clinical study looking at the role of metformin as possible anti-tumor agent ...> Full Article Fruits, vegetables, teas may protect smokers from lung cancer (6/2/2008)Tobacco smokers who eat three servings of fruits and vegetables per day and drink green or black tea may be protecting themselves from lung cancer ...> Full Article Research News: The Structure of XPD Sheds Light on Cancer and Aging (6/2/2008)The role of a unique DNA-repair protein in multiple diseases ...> Full Article Decoy Protein Captures Tumor Growth Factors (6/1/2008)Implications for designing drugs to inhibit cancer ...> Full Article Oral cancers linked to genes as well as lifestyle (5/31/2008)A major international study provides the strongest evidence to date that genetics play a role in oral cancers ...> Full Article Diabetes Doubles Liver Cancer Risk for Patients with Advanced Hepatitis C (5/31/2008)Patients who have chronic hepatitis C with advanced fibrosis have twice the risk of developing liver cancer if they also have diabetes ...> Full Article Dehydrated Tomatoes Show Promise for Preventing Prostate Cancer (5/31/2008)New research suggests that the form of tomato product one eats could be the key to unlocking its prostate cancer-fighting potential ...> Full Article Let there be light (5/28/2008)Photodynamic therapy breakthrough in cancer treatment ...> Full Article New Links in Tobacco Carcinogen Chemical Pathway (5/28/2008)
Major 'missed' biochemical pathway emerges as important in virtually all cells (5/27/2008)A new study provides more evidence that the nitric oxide (NO) system in the life of a cell plays a key role in disease, and the findings point to ways to improve treatment of illnesses such as heart disease and cancer. ...> Full Article Discovery May Lead to Early Cancer Detection (5/27/2008)Researchers have developed antibodies that recognize pancreatic cancer ...> Full Article Researchers find roadmap to next-generation cancer therapies (5/26/2008)Team has discovered an entire novel class of genes they believe will lead to a greater understanding of cancer cell function and the next generation of effective and less harmful therapies for patients. ...> Full Article Experimental agent blocks prostate cancer in animal study (5/26/2008)An experimental drug has blocked the progression of prostate cancer in an animal model with an aggressive form of the disease ...> Full Article New Biological Classification of Ovarian Cancer - A Possibility for Better Survival (5/25/2008)A thesis from The Sahlgrenska Academy shows that it might be possible to predict with great probability which women with ovarian cancer will survive the disease before painful treatment with antineoplastic agents. A better prognosis would considerably improve the quality of life of patients since the treatment could be made more effective and thereby result in fewer side effects. ...> Full Article Stabilizing Cancer-Fighting p53 Can Also Shield a Metastasis-Promoter (5/25/2008)Research shows protecting p53 from degradation also defends its mutant ...> Full Article Researchers Publish Promising Results from Cancer Clinical Trial of JX-594 (5/25/2008)Majority of these end- stage patients with solid tumors had objective tumor destruction and responses following treatment with the cancer biotherapeutic ...> Full Article A new change in the chromosome of patients with esophageal squamous cell carcinoma (5/24/2008)Comparative genomic hybridization analysis provides comprehensive information about relative chromosomal losses and gains in malignant tumors in vitro. ...> Full Article Determining genetic signature of lung tumors can help guide treatment (5/23/2008)Study confirms early use of targeted therapy can improve outcomes, more study needed ...> Full Article A promising tumor gene therapeutic target: tMK (5/23/2008)Midkine (MK), a heparin-binding growth factor, and its truncated form (tMK) are expressed at higher levels in various malignant tumors ...> Full Article New Mechanism Identified for Action of Possible Carcinogen (5/22/2008)Toxicologists have identified a new biological mechanism by which a possible carcinogen - a chemical compound that's widely used in everything from food wrappings to stain-resistant clothing - might increase cancer risk. ...> Full Article Iressa Shows Promise For Treatment of Metastatic Breast Cancer When Combined With Hormonal Therapy (5/21/2008)First positive findings in breast cancer for this class of drugs ...> Full Article New research improves early detection and survival for pancreatic cancer (5/21/2008)New research shows the risk factors for and improve earlier detection of pancreatic cancer. ...> Full Article Researchers Expand Natural Killer Cells In Cord Blood To Fight Leukemia (5/20/2008)Researchers have found a therapy that effectively kills human leukemia cells in mice using natural killer cells from umbilical cord blood. ...> Full Article New Drug Combination Brings One-Two Punch Against Acute Leukemia (5/20/2008)Researchers have discovered a drug combination that kills leukemia cells by shutting down their energy source and hastening cell starvation. ...> Full Article Mapping of prostate cancer genes opens the door to new treatments (5/20/2008)Researchers have identified a specific gene expression profile of prostate cancer stem cells, with important implications for future treatments ...> Full Article Reducing intake of dietary fat prevents prostate cancer in mice (5/19/2008)Finding may lead to new strategies to fight disease in men ...> Full Article Novel Enzyme Inhibitor Paves Way for New Cancer Drug (5/19/2008)Combining natural organic atoms with metal complexes, scientists have developed a new type of enzyme inhibitor capable of blocking a biochemical pathway that plays a key role in cancer development. ...> Full Article Connecting Cancer Genes (5/19/2008)A large genetic study in mice has identified hundreds of genes involved in the development of cancer by examining the DNA of more than 500 lymphomas to find the cancer causing mutations ...> Full Article Tooth Loss Strongly Linked to Risk of Esophageal, Head and Neck, and Lung Cancer (5/18/2008)Studying thousands of patients, Japanese researchers have found a strong link between tooth loss and increased risk of three cancers - esophageal, head and neck, and lung ...> Full Article Genes May Play Role in Risk Assessment for Prostate Cancer Among Hispanics and Caucasians (5/18/2008)Genetic differences may explain the greater risk for prostate cancer among Caucasian men compared with Hispanic men, which could help clinicians predict who is more likely to develop the disease ...> Full Article Keck School Site of Breast Cancer Study (5/17/2008)New report reveals that an ultrasound exam can help detect a larger percentage of cancer while increasing the rate of false positive findings. ...> Full Article Doctors Target the Multiple Facets of Pancreatic Tumors (5/16/2008)Researchers are successfully treating pancreatic cancer patients using multiple novel strategies including a combination therapy on a clinical study designed to choke off a tumor's blood supply. ...> Full Article Chemical Compound Prevents Cancer In Lab (5/15/2008)Researchers study several compounds to stop or prevent cancer ...> Full Article Researchers isolate compound that obstructs cell growth in multiple myeloma and other cancers fueled by certain proteins (5/15/2008)Extract of coconut shrinks tumors by killing cancer cells ...> Full Article Vitamin D Protects Cells from Stress That Can Lead to Cancer (5/14/2008)By inducing a specific gene to increase expression of a key enzyme, vitamin D protects healthy prostate cells from the damage and injuries that can lead to cancer, University of Rochester Medical Center researchers report. ...> Full Article Adding Ultrasound To Mammography May Improve Breast Cancer Detection In High-Risk Women (5/14/2008)The addition of an ultrasound examination to mammography for women at high-risk of breast cancer resulted in a higher rate of cancer detection, but also increased the number of false-positive results ...> Full Article Skin flaps deliver cancer-fighting therapy, ASPS study reveals (5/11/2008)Treatment provides 'blueprint' to produce therapeutic proteins at tumor site ...> Full Article Biochips can detect cancers before symptoms develop (5/11/2008)In their fight against cancer, doctors have just gained an impressive new weapon to add to their arsenal. Researchers at the U.S. Department of Energy's Argonne National Laboratory have developed a chip that can save lives by diagnosing certain cancers even before patients become symptomatic. ...> Full Article New Cancer Gene Discovered (5/10/2008)Researchers reduce protein; stop cancer growth – Plan to develop new cancer therapy target ...> Full Article Previously unseen switch regulates breast cancer response to estrogen (5/10/2008)A tiny modification called methylation on estrogen receptors prolongs the life of these growth-driving molecules in breast cancer cells ...> Full Article Virus mimics human protein to hijack cell division machinery (5/10/2008)Researchers report that a viral protein, called UL97, masquerades as a normal regulatory enzyme to modify a tumor-suppressing protein in human cells. ...> Full Article Switching on cancer killer gene (5/9/2008)Scientists have discovered how to control a major anti-tumour gene that could lead to more effective chemotherapy ...> Full Article Scientists identify interacting proteins key to melanoma development (5/7/2008)Researchers have discovered how a mole develops into melanoma by showing the interaction of two key proteins involved in 60-70 percent of tumors ...> Full Article Cells lining milk ducts hold key to spread of common form of breast cancer, study finds (5/7/2008)When a form of cancer that begins in the milk ducts of the breast invades neighboring tissue to spread to other parts of the body, the cause lies not in the tumor cells themselves but in a group of abnormal surrounding cells that cause the walls of the duct to deteriorate like a rusty pipe ...> Full Article Discovery of a novel mechanism for the development of colon cancer (5/7/2008)New research has shed light on the mechanisms of colon tumor development and may help to design better treatment for this disease. ...> Full Article Combined Physical and Genetic Map Finds Cancer's 'Ignition Key' (5/6/2008)team's whole-organ genomic survey depicts journey from normal to malignant cell ...> Full Article EGFR Protects Cancer Cells from Starving (5/6/2008)A growth factor receptor found abundantly on the surface of cancer cells and long known to fuel cancer growth also protects tumor cells from starvation by a newly identified mechanism ...> Full Article Small Molecule Can Activate an Important Cancer Suppressor Gene (5/4/2008)By activating a cancer suppressor gene, a small molecule called nutlin-3a can block cancer cell division ...> Full Article New discovery linked to DNA repair and cancer (5/4/2008)Scientists have discovered a new protein in humans that plays an important role in repairing DNA damage that could lead to cancer ...> Full Article New study raises questions about prostate cancer therapies targeting insulin-like growth factor receptor (5/3/2008)Therapies under development to treat prostate cancer by inhibiting the ability of insulin-like growth factor (IGF-1) to activate its target receptor could have unexpected results especially if a major tumor suppressor gene - p53 - is already compromised ...> Full Article Getting to the roots of breast cancer (5/2/2008)The lesson learned in eradicating dandelions from your yard could apply in treating breast cancer ...> Full Article Biomarker Predicts Malignancy Potential of HG-PIN Lesions in the Prostate (5/2/2008)Men whose prostate cancer screenings show high grade prostatic intraepithelial neoplasia (HG-PIN) may find themselves in limbo, "stuck" between diagnoses - they are told prostate cancer has not yet developed, but it might, and they are advised to undergo repeated needle biopsies as a precaution. ...> Full Article Early treatment of stomach infection may prevent cancer (5/2/2008)Based on research using a new mouse model of gastritis and stomach cancer, researchers say that prompt treatment of Helicobacter pylori (H. pylori) infections reverses damage to the lining of the stomach that can lead to cancer. ...> Full Article 'Destruct' triggers may be jammed in tumor cells, geneticists say (5/1/2008)Tumor cells living in the cross hairs of radiation or chemotherapy may be able to escape death because their self-destruct mechanisms are jammed ...> Full Article New lymphoma therapies targets diverse and difficult cancer (4/29/2008)New treatments for the disease, giving hope to the more than one million lymphoma patients worldwide ...> Full Article Scientists at Yale Provide Explanation for How Cancer Spreads (4/29/2008)Metastasis, the spread of cancer throughout the body, can be explained by the fusion of a cancer cell with a white blood cell in the original tumor. This single event can set the stage for cancer's migration to other parts of the body. ...> Full Article Potential viral therapy weapon for difficult cancers is safe and effective in study (4/28/2008)Combining a herpes virus genetically altered to express a drug-enhancing enzyme with a chemotherapy drug effectively and safely reduced the size of highly malignant human sarcoma grafted into mice ...> Full Article Cancer immunotherapy shows long-term promise in lung cancer (4/27/2008)New, long-term results from a clinical trial an immune-boosting treatment for lung cancer patients, reduces the risk of relapse after surgery -- to the same extent as chemotherapy but without the side-effects of chemotherapy. ...> Full Article Doctor Urges Early Diagnosis To Avoid Cancer's 'Forgotten Killer' (4/26/2008)On average, two Marylanders each day are diagnosed with potentially fatal oral cancers that are often curable if identified and treated early ...> Full Article Melanoma Lurks in Larger Skin Lesions, Researchers Find (4/26/2008)Skin lesions that are about the size of a pencil eraser are more likely to be melanomas, a deadly form of skin cancer, than smaller moles ...> Full Article Standard chemo works better against metastatic BRCA1/2 breast cancer than against sporadic tumors (4/25/2008)he first study to investigate the effects of chemotherapy on metastatic breast cancer in women with the BRCA1 or BRCA2 gene mutation has shown that standard chemotherapy works better in these patients than in women without the BRCA1/2 mutation. ...> Full Article Scientists Discover a Mechanism That Can Send Cells on the Road to Cancer (4/25/2008)Adenoviral protein E1A binds to p400, stabilizing Myc, an oncoprotein ...> Full Article Researchers reveal structure of protein that repairs damage to cancer cells (4/24/2008)A team of scientists has shown how two proteins locate and repair damaged genetic material inside cells. ...> Full Article Cancer cells spread by releasing 'bubbles' (4/24/2008)Cancer cells are able to communicate with their more healthy counter-parts by releasing vesicles ...> Full Article Primary driver of stomach cancer development identified (4/23/2008)Potential new drug targets ...> Full Article Scientists obtain anticancer medicines from the elecampe, a wild plant growing in the Mediterranean (4/23/2008)Researchers state that the plant can also be used for antimigraine drugs. ...> Full Article Particular Experimental Therapy Not More Effective Than Standard Treatment For Anal Canal Cancer (4/23/2008)Use of chemotherapy with the drug cisplatin before other treatments did not improve disease-free survival for patients with anal canal cancer compared to the standard treatment regimen, and resulted in a higher rate of colostomy procedures ...> Full Article Drug Compound Leads to Death of Ovarian Cancer Cells Resistant to Chemotherapy (4/22/2008)In a discovery that may be useful for maintaining remission in chemo-resistant ovarian cancer, Yale scientists report that pre-clinical studies have shown the drug compound NV-128 can induce the death of ovarian cancer cells by halting the activation of a protein pathway called mTOR. ...> Full Article Ovarian Cancer Stem Cells Identified, Characterized and Cloned, Leading to More Effective Treatment (4/21/2008)Researchers have identified, characterized and cloned ovarian cancer stem cells and have shown that these stem cells may be the source of ovarian cancer's recurrence and its resistance to chemotherapy. ...> Full Article Screening or treatment for prostate cancer? (4/21/2008)Is screening or treatment for prostate cancer the reason for decreased mortality in the USA, compared to the UK? ...> Full Article Researchers identify key target for cancer therapies (4/21/2008)New therapies must target a key protein interaction to destroy aggressive cancer cells' protective force field ...> Full Article Researchers discover a method for clamping down on a cancer-promoting enzyme (4/20/2008)Researchers have now identified a molecule capable of shutting down cancerous gene before the enzyme becomes active ...> Full Article Inherited Cancer Mutation Is Widespread In America (4/20/2008)A gene mutation responsible for the most common form of inherited colon cancer is older and more common than formerly believed ...> Full Article Main contact a clue in the battle against cancer (4/19/2008)By cutting off the nutritional supply to tumours through treacherous blood vessels, it will perhaps be possible to gain ground in the battle against cancer. ...> Full Article Study finds effective colon cancer prevention treatment (4/19/2008)Drug combination reduces cancer risk with reduced toxic side effects ...> Full Article Gene Variations, Alcohol, and an Association with Breast Cancer Risk (4/18/2008)Specific variations within two genes involved with alcohol metabolism are associated with an increased risk for breast cancer in postmenopausal women ...> Full Article Calorie Restriction Limits and Obesity Fuels Development of Epithelial Cancers (4/18/2008)Team connects dietary balance to common cancer pathways ...> Full Article Tiny magnets offer breakthrough in gene therapy for cancer (4/18/2008)A revolutionary cancer treatment using microscopic magnets to enable 'armed' human cells to target tumours has been developed ...> Full Article In Lab Study, Researchers Find Molecule That Disrupts Ewing's Sarcoma Oncogene (4/17/2008)Researchers have found a small molecule they say can block the action of the oncogene that causes Ewing's sarcoma, a rare cancer found in children and young adults. If further studies continue to prove beneficial, they say the novel agent could be the first targeted therapy to treat the disease, which can produce tumors anywhere in the body. ...> Full Article New Zealand cancer drug gets closer to approval (4/17/2008)A drug discovered has reached the final stage of testing before getting approval to treat cancer patients. ...> Full Article Chemotherapy may not affect memory in breast cancer patients (4/17/2008)Women receiving chemotherapy for breast cancer frequently report problems with memory and concentration. However, two new studies suggest that the stress of the diagnosis - not the chemotherapy - is the cause of these problems. ...> Full Article Eating less fat may prevent prostate cancer, study shows (4/17/2008)Scientists have shown that lowering the intake of the type of fat common in the Western diet helps prevent prostate cancer in mice ...> Full Article Research Pushes Back Threshold of Early Cancer Detection (4/16/2008)The new technology uses light to detect pre-cancerous cells. ...> Full Article Low Dose DFMO Reduces Colon Cancer Risk without Toxicity (4/16/2008)A combination of the targeted agent difluoromethylornithine (DFMO) at a low dose and sulindac, a non-steroidal anti-inflammatory drug (NSAID), reduces the risk of recurrent colorectal adenomas, an early sign of colon cancer, by up to 95 percent with less toxicity than with chemotherapy, researchers report. ...> Full Article Sunitinib May Slow Growth and Spread of Liver Cancer (4/16/2008)Treatment with sunitinib slows tumor growth and reduces the risk of metastasis in patients with hepatocellular carcinoma, an aggressive cancer of the liver, researchers report. ...> Full Article New Molecule Shows Promise in Patients with Advanced Basal Cell Carcinoma (4/16/2008)A novel molecule, GDC-0449, shrinks tumors for patients with advanced basal cell carcinoma with limited side effects, suggesting a viable new treatment option for patients with the advanced form of this cancer ...> Full Article Researchers find targeted therapy combination overcomes treatment resistance in liver cancer (4/15/2008)Researchers report that combining two targeted therapies overcomes treatment resistance in liver cancer cell lines ...> Full Article Eating Soy Foods In Puberty Protects Against Breast Cancer, Evidence Now Suggests (4/14/2008)Evidence is growing from animal and human studies that genistein, a potent chemical found in soy, protects against development of breast cancer - but only if consumed during puberty ...> Full Article Secrets of cellular signaling shed light on new cancer stem cell therapies (4/13/2008)By revealing the inner workings of a common cell-to-cell signaling system, biologists have uncovered new clues about mysterious and contentious creatures called cancer stem cells. ...> Full Article Unusual Skin Cancer May Indicate Colon Cancer Syndrome (4/13/2008)An unusual form of skin cancer may be a sign of an underlying syndrome that makes people more susceptible to certain other cancers ...> Full Article Looping genes may hold a key to understanding breast cancer (4/13/2008)Researchers have discovered how a particular gene associated with breast cancer behaves, which may lead to better testing for the debilitating disease. ...> Full Article Too Identify me is to know me (4/12/2008)The idea of finding a single metabolite biomarker that can unambiguously diagnose a disease is a beguiling one, but unfortunately not currently supported by reality. Although researchers have reported the discovery of a whole range of potential biomarkers for numerous diseases, they often don't stand up to closer scrutiny. But now, by combining together a whole range of different analytical and statistical techniques, a team of Chinese and German chemists may just have improved the chances of detecting a proper biomarker. ...> Full Article Cancer stem cells created with technique developed (4/12/2008)With a bit of genetic trickery, researchers have turned normal skin cells into cancer stem cells, a step that will make these naturally rare cells easier to study. ...> Full Article Extracts from reishi mushroom and green tea shows synergistic effect to slow sarcoma (4/11/2008)New study has found that combining the active ingredients in the mushroom and the tea creates synergetic effects that inhibited the growth of tumors and delayed the time of death in mice with sarcomas. ...> Full Article New regulatory circuit identified for aggressive, malignant brain tumor (4/10/2008)Research using a newly developed algorithm has significantly advanced understanding of the molecular events associated with the most common primary brain tumor in adults, human glioblastoma ...> Full Article An unexpected way to cause leukaemia (4/10/2008)New mouse model grants insight into the genetic and molecular mechanisms underpinning acute myeloid leukaemia ...> Full Article Oklahoma-based cancer test helps stop a killer (4/10/2008)It took 14 years for Oklahoma City biotechnology company InterGenetics to research and develop its breast cancer risk assessment test, OncoVue. But less than a year after becoming commercially available, the test has already begun paying dividends to patients. ...> Full Article New Drug Targets Three Kinds of Leukemia (4/9/2008)Researchers have helped move a new leukemia drug into clinical trials ...> Full Article T-Cadherin Affects Blood Vessel Growth in Breast Cancer, Hormone from Fat Cells May Play a Role (4/8/2008)Researchers may have found a new option for targeted breast cancer therapy by showing the link between a certain protein and the formation and development of blood vessels that feed breast tumors ...> Full Article New research to unlock mysteries of brain cancer, stroke (4/7/2008)New studies will delve into some of the crucial issues surrounding death by brain tumours and stroke ...> Full Article Brain Tumor Patients Benefit From Chemotherapy Pill (4/7/2008)At home chemotherapy pill may be useful for brain tumor patients ...> Full Article Human breast tumors' 'microenvironment' primes them for metastasis (4/7/2008)The environment within primary breast tumors can 'empower' cells that break free and enter the bloodstream to successfully invade other organs ...> Full Article Researchers learn how signaling molecule orchestrates breast cancer's spread (4/6/2008)A study has uncovered how breast tumors use a particular type of molecule to promote metastasis -- the spread of cancer cells. Metastasis is the cause of approximately 90 percent of all cancer-related deaths ...> Full Article Enzyme complex could be key to new cancer treatments (4/6/2008)Scientists are the first to observe in living cells a key step in the creation of adenine and guanine, two of the four building blocks that comprise DNA. ...> Full Article New therapeutic targets to stop breast cancer metastasis to the lung (4/6/2008)A study reveals how breast tumors use a specific type of molecule to promote metastasis - the spread of cancer cells. Metastasis is the cause of approximately 90% of all deaths caused by cancer ...> Full Article Increased Life Expectancy Seen For Patients with Advanced Colorectal, Ovarian and Testicular Cancer (4/5/2008)A new study indicates that patients receiving treatments for late stage testicular, colorectal and ovarian cancer have increased life expectancy, resulting from the proportion of patients cured or by prolonging survival among non-cured ...> Full Article Genetic Variations Raise Lung Cancer Risk for Smokers and Ex-Smokers (4/5/2008)Team finds first common genomic pieces to lethal puzzle ...> Full Article Chemotherapy-induced Anemia Increases Risk of Local Breast Cancer Recurrence (4/4/2008)Patients with breast cancer who developed anemia during chemotherapy had nearly three times the risk of local recurrence as those who did not ...> Full Article Researcher Links Hormone Replacement Therapy to Breast Cancer (4/4/2008)Study finds that use of synthetic hormone could proliferate human tumor cells ...> Full Article Potential association of type 2 diabetes genes with prostate cancer (4/3/2008)Scientists have identified six new genes which play a role in the development of type 2 diabetes, and among the group is the second gene known to also play a role in prostate cancer ...> Full Article The Immune System and Cancer (3/31/2008)New Insights into a Not Always Healthy Interplay ...> Full Article Mobile Cancer Stem Cells - The Real Bad Guy? (3/31/2008)New Model of Metastasis Formation Presented ...> Full Article New Study Finds Exposure to Low Levels of Radon Appears to Reduce the Risk of Lung Cancer (3/29/2008)Exposure to levels of radon gas typically found in 90 percent of American homes appears to reduce the risk of developing lung cancer by as much as 60 percent, according to a study published in the March issue of the journal Health Physics. The finding differs significantly from the results of previous case-control studies of the effects of low-level radon exposure, which have detected a slightly elevated lung cancer risk (but without statistical significance) or no risk at all. ...> Full Article Grant Focuses on Link Between Chemical Exposure and Prostate Cancer (3/29/2008)With questions lingering about the estrogen-mimicking chemical Bisphenol A, anenvironmental health expert hopes to shed new light on the relationship between the man-made chemical and prostate cancer. ...> Full Article Basis created for directing and filming blood vessels (3/28/2008)A new method of filming blood-vessel cells that move in accordance with targeted signals has been developed ...> Full Article Multi-Institutional Study Identifies New Form of Inherited Risk of Cancer (3/28/2008)Genetic Analysis of Colon Cancer Patients Reveals Higher Levels of Autozygosity - Identical Copies of DNA Inherited From Both Parents - Than Controls ...> Full Article Mounting evidence shows red wine antioxidant kills cancer (3/28/2008)Researchers pinpoint how resveratrol induces pancreatic cancer cell death ...> Full Article Spit Tests May Soon Replace Many Blood Tests (3/27/2008)Easy-Access Body Fluid May Provide Less Invasive Diagnosis Thanks to Proteomics ...> Full Article Review Of Group-Based Cancer Trials Reveals Flaws In Studies' Design And Analysis (3/27/2008)A new study reviewing 75 group-randomized cancer trials over a five-year stretch shows that fewer than half of those studies used appropriate statistical methods to analyze the results. The review suggests that some trials may have reported that interventions to prevent disease or reduce cancer risks were effective when in fact they might not have been. ...> Full Article Scientists Discover New Way of Selectively Killing Cancer Cells (3/27/2008)A professor has discovered a chemical mechanism that can selectively kill cancer cells while leaving normal cells unharmed. ...> Full Article Apple pectin, apple juice extracts shown to have anticarcinogenic effects on colon (3/27/2008)The apples and apple juice you consume may have positive effects in one of the most unlikely places in the body - in the colon. New research has demonstrated that both apple pectin and polyphenol-rich apple juice components actually enhance biological mechanisms that produce anticarcinogenic compounds during the fermentation process. ...> Full Article Cancer Treatments In Phase 3 Trials Successful Up To Half Of The Time (3/26/2008)About one-fourth to one-half of new cancer treatments that reach assessment in phase 3 randomized clinical trials are eventually proven successful ...> Full Article Coming soon: Cell therapies for diabetes, cancer? (3/24/2008)Therapies using stem cell transplants are advancing promising treatments for such conditions as Alzheimer's Disease, neurological diseases and spinal cord injury, and heart disease. Now, scientists think that stem cell transplants may ultimately benefit those who suffer from diabetes or cancer. However, important questions need answers: Given the shortage of human pancreatic islet tissue, can stem cells be used to provide insulin cells that can be stored and secreted from a bioartifical pancreas? Can islet cells be frozen for long periods of time, retain their integrity and be transplanted? If tumors contain cancer stem cells, how can the stem cells be targeted and destroyed to provide improved therapies? ...> Full Article Scans spot hidden tumors in rare cancer syndrome (3/24/2008)Study suggests PET/CT may have value in screening Li-Fraumeni patients ...> Full Article Subterfuge, counter-surveillance and assassination: The body's fight with cervical cancer (3/23/2008)The virus responsible for most cases of cervical cancer has a serious weakness which may provide hope for new treatments for the disease. ...> Full Article Scientists report first 3-D view of anti-cancer agent (3/22/2008)Researchers have created the first three-dimensional image of how a well-established chemotherapy agent targets and binds to DNA ...> Full Article Researchers unmask proteins in telomerase, a substance that enables cancer (3/22/2008)One of the more intriguing workhorses of the cell, a protein conglomerate called telomerase, has in its short history been implicated in some critical areas of medicine including cancer, aging and keeping stem cells healthy. With such a resume, telomerase has been the subject of avid interest by basic scientists and pharmaceutical companies alike, so you'd think at the very least people would know what it is. ...> Full Article Scientists show that a microRNA can reduce lung cancer growth (3/21/2008)A small RNA molecule, known as let-7 microRNA (miRNA), substantially reduced cancer growth in multiple mouse models of lung cancer ...> Full Article Modified Virus Vaccine Shows Breast Cancer Promise (3/18/2008)Researchers have shown that vaccinating mice with a modified form of a virus containing proteins from breast cancer cells can kill large breast cancer tumors and tumors that have spread to the lungs. The rodent model of cancer used in this study closely resembles a type of breast cancer seen in humans called HER2-positive. Although other cancer vaccines have shown activity in the treatment of very small tumors, their ability to influence large, established tumors, such as many HER2-positive breast cancers, has proven difficult. The study, led by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, appeared in the March 15, 2008, issue of Cancer Research. ...> Full Article Tanning, Sun Exposure Increase Risk For Early Skin Cancer (3/18/2008)Teen-agers are flocking to tanning beds in record numbers, despite repeated cancer warnings from physicians. Shari Croy was one of those golden-brown teen-agers. Now 46, she's battling skin cancer. ...> Full Article Gene Variant Increases Breast Cancer Risk (3/18/2008)Researchers have shown that a common gene variant increases the risk of developing breast cancer. ...> Full Article Soy compound may halt spread of prostate cancer (3/16/2008)A compound found in soybeans almost completely prevented the spread of human prostate cancer in mice ...> Full Article Is increased Slug expression associated with the progression to esophageal cancer? (3/16/2008)Real-time reverse transcription-polymerase chain reaction (RT-PCR), semi-quantitative immunohistochemistry and tissue array reveal that the progression to adenocarcinoma is associated with increased Slug expression and this may represent a mechanism of E-cadherin silencing ...> Full Article A protein that triggers aggressive breast cancer (3/15/2008)SATB1 is a nuclear protein well known for its crucial role in regulating gene expression during the differentiation and activation of T cells, making it a key player in the immune system. But SATB1 has now revealed a darker side: it is an essential contributing factor in the most aggressive forms of breast cancer. ...> Full Article Study helps explain fundamental process of tumor growth (3/15/2008)Unique metabolic process first identified eight decades ago is found to be key ...> Full Article Researchers Highlight Anti-Cancer Benefits of Vitamin D (3/14/2008)Vitamin D has long been recognized for its role in making healthy bones, but a growing body of evidence now suggests that it can also significantly reduce the risk of developing several types of cancers. ...> Full Article Researchers ID behavioral risk factors for head and neck cancers (3/13/2008)Sex practices and lifestyle are culprits ...> Full Article Recurrent Low-Grade Carcinoma of the Ovary Less Responsive to Chemotherapy Than More Common Ovarian Cancers (3/12/2008)The retrospective study is the first to analyze how women with low-grade tumors respond to chemotherapy in recurrent setting and confirms clinical impressions that the tumors are chemoresistant, said lead author David M. Gershenson, M.D., professor and chair of the Department of Gynecologic Oncology at M. D. Anderson. Previous studies have shown similar tumor resistance in newly diagnosed patients, and there is currently no standard of care for women facing the disease. ...> Full Article Researchers demonstrate protective role of microRNA (3/11/2008)Genetic snippets linked to cancer also key to embryonic cell development ...> Full Article Researchers identify colorectal cancer gene (3/11/2008)Study is a step towards the future of genetic testing for the third most commonly diagnosed cancer in Americans ...> Full Article Researchers find potential cancer drug (3/9/2008)
Non-Hodgkin Lymphoma Mutations Yield New Therapy Clues (3/8/2008)DNA mutations found in a type of non-Hodgkin lymphoma that has a poor prognosis has led researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, and their colleagues to a better understanding of how the cancer develops and how it might be treated. ...> Full Article Researchers identify new genetic marker for breast cancer (3/7/2008)An international group of investigators led by scientists at Memorial Sloan-Kettering Cancer Center (MSKCC) and the National Cancer Institute has identified a new genetic marker of risk for breast cancer. Women with this DNA variation are at a 1.4 times greater risk of developing breast cancer compared to those without the variation. The findings are to be published online on March 3, 2008 in the journal Proceedings of the National Academy of Sciences. ...> Full Article Scientists discover how cigarette smoke causes cancer (3/6/2008)Everyone has known for decades that that smoking can kill, but until now no one really understood how cigarette smoke causes healthy lung cells to become cancerous. In a new research report published in the March 2008 print issue of The FASEB Journal, researchers from the University of California, Davis, show that hydrogen peroxide (or similar oxidants) in cigarette smoke is the culprit. ...> Full Article Family Of Liver Cancer Genes Discovered (3/6/2008)An interdisciplinary team of researchers at Stony Brook University Medical Center has identified a family of genes linked to the development of liver cancer. Principal Investigator Wadie F. Bahou, M.D., Professor of Medicine and Genetics, and colleagues discovered in a mouse model that the loss of one specific gene (Iqgap2) in this family causes Hepatocellular carcinoma (HCC). They also found that when another member of the gene family (Iqgap1) is turned on, a more aggressive form of the disease occurs. ...> Full Article Protein protects lung cancer cells from efforts to fix or kill them (3/5/2008)A protein that helps lung cancer cells thrive appears to do so by blocking healthy cells' ability to fix themselves when radiation or chemicals such as nicotine damage their DNA, according to a University of Florida study to be published Friday (Feb. 29) in the journal Molecular Cell. ...> Full Article Thalidomide Shows Promise For Treatment Of Recurrent Ovarian Cancer, Study Suggests (3/5/2008)Thalidomide, a drug blamed in the 1950s for causing birth defects, is now showing promise as a safe and effective treatment for women with recurrent ovarian cancer, according to a study led by a University of Minnesota Cancer Center researcher. ...> Full Article Protein in embryonic stem cells control malignant tumor cells (3/5/2008)A protein that governs development of human embryonic stem cells (hESCs) also inhibits the growth and spread of malignant melanoma, the deadliest skin cancer, Northwestern University researchers have discovered. Metastatic melanoma, which develops from the transformation of skin pigment cells or melanocytes, has a death rate of more than 80 percent and a median survival of less than 7.5 months. ...> Full Article Extract of broccoli sprouts may protect against bladder cancer (3/4/2008)
New blood marker may predict prostate cancer spread (3/4/2008)Information could lead to more accurate prediction of cancer metastasis thereby improving patient management. ...> Full Article Tumor Vaccines Developed by Researchers (3/4/2008)A new study reveals how Keck School researchers have discovered a new molecular player that will help create a better vaccination against tumors. ...> Full Article Red Meat Consumption Linked to Colorectal Cancer (3/4/2008)
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