All Articles Tagged As: breast cancer

Genetic profiling for breast cancer on the horizon (6/28/2008)

Scientists have shown it may soon be possible to offer women a genetic test to assess their risk of breast cancer which could aid early diagnosis for those at high risk of the disease. ...> Full Article

Team discovers new inhibitors of estrogen-dependent breast cancer cells (6/24/2008)

Researchers have discovered a new family of agents that inhibit the growth of estrogen-dependent breast cancer cells. ...> Full Article

Scientists find 5 genes involved in the metastasis of breast tumours to the lung (6/24/2008)

According to the results of this study, of the five genes identified, the Tenascina-C gene seems to be a good therapeutic target for the treatment of metastatic breast cancer. ...> Full Article

Improving understanding of cell behaviour in breast cancer (6/23/2008)

Researchers are combining a number of approaches in a dynamic effort to improve our understanding of cell behaviour in breast cancer ...> Full Article

New possibilities for breast cancer treatment on the horizon (6/17/2008)

Custom-built breast PET/CT scanner could advance breast cancer treatment, ...> Full Article

Raloxifene reduces risk of invasive estrogen-receptor positive breast cancer (6/14/2008)

Women who took raloxifene were less likely to develop invasive estrogen-receptor (ER) positive breast cancer compared with women who did not ...> Full Article

Anti-estrogen Drug Therapy Reduces Risk of Invasive Breast Cancer in Older Women (6/13/2008)

New analysis of a drug approved for osteoporosis prevention and treatment has provided definitive evidence that the medication is also effective as a breast cancer preventative for certain cancers. ...> Full Article

Metformin Increases Pathologic Complete Response Rates in Breast Cancer Patients With Diabetes (6/3/2008)

First clinical study looking at the role of metformin as possible anti-tumor agent ...> Full Article

Iressa Shows Promise For Treatment of Metastatic Breast Cancer When Combined With Hormonal Therapy (5/21/2008)

First positive findings in breast cancer for this class of drugs ...> Full Article

Keck School Site of Breast Cancer Study (5/17/2008)

New report reveals that an ultrasound exam can help detect a larger percentage of cancer while increasing the rate of false positive findings. ...> Full Article

Adding Ultrasound To Mammography May Improve Breast Cancer Detection In High-Risk Women (5/14/2008)

The addition of an ultrasound examination to mammography for women at high-risk of breast cancer resulted in a higher rate of cancer detection, but also increased the number of false-positive results ...> Full Article

Previously unseen switch regulates breast cancer response to estrogen (5/10/2008)

A tiny modification called methylation on estrogen receptors prolongs the life of these growth-driving molecules in breast cancer cells ...> Full Article

Cells lining milk ducts hold key to spread of common form of breast cancer, study finds (5/7/2008)

When a form of cancer that begins in the milk ducts of the breast invades neighboring tissue to spread to other parts of the body, the cause lies not in the tumor cells themselves but in a group of abnormal surrounding cells that cause the walls of the duct to deteriorate like a rusty pipe ...> Full Article

Getting to the roots of breast cancer (5/2/2008)

The lesson learned in eradicating dandelions from your yard could apply in treating breast cancer ...> Full Article

Standard chemo works better against metastatic BRCA1/2 breast cancer than against sporadic tumors (4/25/2008)

he first study to investigate the effects of chemotherapy on metastatic breast cancer in women with the BRCA1 or BRCA2 gene mutation has shown that standard chemotherapy works better in these patients than in women without the BRCA1/2 mutation. ...> Full Article

Gene Variations, Alcohol, and an Association with Breast Cancer Risk (4/18/2008)

Specific variations within two genes involved with alcohol metabolism are associated with an increased risk for breast cancer in postmenopausal women ...> Full Article

Chemotherapy may not affect memory in breast cancer patients (4/17/2008)

Women receiving chemotherapy for breast cancer frequently report problems with memory and concentration. However, two new studies suggest that the stress of the diagnosis - not the chemotherapy - is the cause of these problems. ...> Full Article

Research Pushes Back Threshold of Early Cancer Detection (4/16/2008)

The new technology uses light to detect pre-cancerous cells. ...> Full Article

Eating Soy Foods In Puberty Protects Against Breast Cancer, Evidence Now Suggests (4/14/2008)

Evidence is growing from animal and human studies that genistein, a potent chemical found in soy, protects against development of breast cancer - but only if consumed during puberty ...> Full Article

Looping genes may hold a key to understanding breast cancer (4/13/2008)

Researchers have discovered how a particular gene associated with breast cancer behaves, which may lead to better testing for the debilitating disease. ...> Full Article

Oklahoma-based cancer test helps stop a killer (4/10/2008)

It took 14 years for Oklahoma City biotechnology company InterGenetics to research and develop its breast cancer risk assessment test, OncoVue. But less than a year after becoming commercially available, the test has already begun paying dividends to patients. ...> Full Article

T-Cadherin Affects Blood Vessel Growth in Breast Cancer, Hormone from Fat Cells May Play a Role (4/8/2008)

Researchers may have found a new option for targeted breast cancer therapy by showing the link between a certain protein and the formation and development of blood vessels that feed breast tumors ...> Full Article

New therapeutic targets to stop breast cancer metastasis to the lung (4/6/2008)

A study reveals how breast tumors use a specific type of molecule to promote metastasis - the spread of cancer cells. Metastasis is the cause of approximately 90% of all deaths caused by cancer ...> Full Article

Researchers learn how signaling molecule orchestrates breast cancer's spread (4/6/2008)

A study has uncovered how breast tumors use a particular type of molecule to promote metastasis -- the spread of cancer cells. Metastasis is the cause of approximately 90 percent of all cancer-related deaths ...> Full Article

Chemotherapy-induced Anemia Increases Risk of Local Breast Cancer Recurrence (4/4/2008)

Patients with breast cancer who developed anemia during chemotherapy had nearly three times the risk of local recurrence as those who did not ...> Full Article

Researcher Links Hormone Replacement Therapy to Breast Cancer (4/4/2008)

Study finds that use of synthetic hormone could proliferate human tumor cells ...> Full Article

Gene Variant Increases Breast Cancer Risk (3/18/2008)

Researchers have shown that a common gene variant increases the risk of developing breast cancer. ...> Full Article

Modified Virus Vaccine Shows Breast Cancer Promise (3/18/2008)

Researchers have shown that vaccinating mice with a modified form of a virus containing proteins from breast cancer cells can kill large breast cancer tumors and tumors that have spread to the lungs. The rodent model of cancer used in this study closely resembles a type of breast cancer seen in humans called HER2-positive. Although other cancer vaccines have shown activity in the treatment of very small tumors, their ability to influence large, established tumors, such as many HER2-positive breast cancers, has proven difficult. The study, led by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, appeared in the March 15, 2008, issue of Cancer Research. ...> Full Article

A protein that triggers aggressive breast cancer (3/15/2008)

SATB1 is a nuclear protein well known for its crucial role in regulating gene expression during the differentiation and activation of T cells, making it a key player in the immune system. But SATB1 has now revealed a darker side: it is an essential contributing factor in the most aggressive forms of breast cancer. ...> Full Article

Researchers identify new genetic marker for breast cancer (3/7/2008)

An international group of investigators led by scientists at Memorial Sloan-Kettering Cancer Center (MSKCC) and the National Cancer Institute has identified a new genetic marker of risk for breast cancer. Women with this DNA variation are at a 1.4 times greater risk of developing breast cancer compared to those without the variation. The findings are to be published online on March 3, 2008 in the journal Proceedings of the National Academy of Sciences. ...> Full Article

Enzyme reinforces tumor-causing role of the nuclear coactivator SRC-3 (3/3/2008)

High levels of the enzyme atypical protein kinase C (aPKC) increases the activity of the cancer-associated protein steroid receptor coactivator-3 (SRC-3) in cancer cells that depend on estrogen to promote their growth, said researchers at Baylor College of Medicine in Houston in a report that appears in the current issue of the journal Molecular Cell. ...> Full Article

Chicken Antibodies To Help Detect HER2 Breast Cancer (2/27/2008)

Generations of mothers have served up chicken soup to remedy the common cold, but now the therapeutic fowl may find use in diagnosis as well. Researchers at the National Institute of Standards and Technology (NIST), the National Cancer Institute (NCI) and the scientific research firm SAIC recently showed how chicken antibodies may one day improve the detection of an aggressive form of breast cancer. ...> Full Article

New findings for breast cancer survivors (2/15/2008)

New findings from a clinical trial coordinated at Queen's University show that women who survive breast cancer - the most common form of cancer among Canadian women - are more likely to die from other causes. The results were particularly striking for older women. ...> Full Article

Researcher Examines Link Between Cancer, Down Syndrome (2/6/2008)

There's new hope for breast cancer research, and it's coming from a very unlikely place. Researchers at the Texas A&M University College of Veterinary Medicine & Biomedical Sciences recently published articles in the journals Molecular and Cellular Biology and Carcinogenesis indicating that a protein long suspected to play a role in Down syndrome may also contribute to treating this devastating disease. ...> Full Article

New Genetic Barcoding Technique Identifies Dozens of Targets for Cancer Drugs (2/3/2008)

Investigators have invented a quick and relatively inexpensive method for identifying genes that are indispensable for the growth and survival of colon and breast cancer cells. ...> Full Article

BRCA1 mutation linked to breast cancer stem cells (2/3/2008)

Research sheds light on why women with this gene mutation have higher risk of breast cancer ...> Full Article

Two pieces of DNA linked to breast cancer metastasis (2/1/2008)

Two MicroRNAs Promote Spread of Tumor Cells: MiR-373 Could Be Indicator of Breast Cancer Metastasis ...> Full Article

Will Breast Cancer Spread? (10/17/2007)

One of the many unknowns facing women who are diagnosed with breast cancer is the likelihood that the cancer will spread to other parts of the body – metastasize. Researchers are looking to change that. Bioengineering professor is pioneering a more accurate approach for predicting the risk of breast cancer metastasis in individual patients. ...> Full Article