All Articles Tagged As: brain tumors

Researchers discover new way to kill pediatric brain tumors (2/17/2010)

Researchers have identified a previously unrecognized target, a protein called STAT3, at which they can aim new drugs for the treatment of cancer in neurofibromatosis-1 (NF1), a genetic condition that causes increased risk of benign and malignant brain tumors. ...> Full Article

Cancer stem cells suppress immune response against brain tumor (1/23/2010)

Cancer-initiating cells that launch glioblastoma multiforme, the most lethal type of brain tumor, also suppress an immune system attack on the disease, scientists from the University of Texas M. D. Anderson Cancer Center report in a paper featured on the cover of the Jan. 15 issue of Clinical Cancer Research. ...> Full Article

Researchers report benefits of new standard treatment study for rare pediatric brain cancer (10/13/2009)

A team of researchers led by the University of Texas M. D. Anderson Cancer Center unveiled results today from the largest-ever collaborative study addressing the treatment of a rare pediatric brain tumor. The findings suggest a new standard protocol could improve survival nearly two-fold for pediatric patients with choroid plexus tumors, as reported at the 41st Annual Meeting of the International Society of Pediatric Oncology. ...> Full Article

New approach for the treatment of malignant brain tumors (10/6/2009)

Initial chemotherapy alone after surgery is just as successful as initial radiation therapy for patients from whom a very malignant brain tumor (anaplastic glioma) was removed. With this treatment, the patients survive on average more than 30 months without a recurrence. A study conducted by the Neurooncology Working Group of the German Cancer Society led by researchers from Heidelberg and Zürich showed that patients in primary therapy benefit to the same extent from chemotherapy alone as from radiation alone. ...> Full Article

A crystal ball for brain cancer? (7/31/2009)

New UCLA method predicts which brain tumors will respond to drug ...> Full Article

DNA variations linked to brain tumors (7/7/2009)

Mayo Clinic researchers and colleagues at the University of California San Francisco have found a connection between DNA alterations on human chromosome 9 and aggressive brain cancer known as glioblastoma. ...> Full Article

Tumor suppressor gene in flies may provide insights for human brain tumors (6/23/2009)

In the fruit fly's developing brain, stem cells called neuroblasts normally divide to create one self-renewing neuroblast and one cell that has a different fate. But neuroblast growth can sometimes spin out of control and become a brain tumor. Researchers at Duke-NUS Graduate Medical School in Singapore have found a tumor-suppressing protein in the fly's brain, with a counterpart in mammals, that can apparently prevent brain tumors from forming. ...> Full Article

Most common brain cancer may originate in neural stem cells (6/3/2009)

Findings in mice suggest greater hope for targeting brain cancer, but also greater caution in pursuing stem cell treatments for degenerative diseases ...> Full Article

Computer model predicts brain tumor growth and evolution (5/21/2009)

Scientists from Brown University, the University of Texas and elsewhere have developed a computational computer model that tracks brain tumor growth virtually and can be matched to real tumors. The new computer model could lead to specific, targeted treatments for individualized therapy. Details are in the May 15 edition of the journal Cancer Research. ...> Full Article

Researchers discover possible way to block the spread of deadly brain tumors (4/20/2009)

Researchers at the Translational Genomics Research Institute may have found a way to stop the often-rapid spread of deadly brain tumors. A gene with the playful-sounding name NHERF-1 may be a serious target for drugs that could prevent malignant tumors from rapidly multiplying and invading other parts of the brain, according to a cover story in this month's edition of Neoplasia, an international journal of cancer research. ...> Full Article

Study finds biological clue in brain tumor development (3/24/2009)

Scientists at the University of Nottingham have uncovered a vital new biological clue that could lead to more effective treatments for a children's brain tumor that currently kills more than 60 percent of young sufferers. ...> Full Article

Brain tumor treatment may increase number of cancer stem-like cells (3/9/2009)

A new study suggests that the standard treatment for a common brain tumor increases the aggressiveness of surviving cancer cells, possibly leaving patients more vulnerable to tumor recurrence. The research, published by Cell Press in the March 6 issue of the journal Cell Stem Cell, provides valuable insight into the molecular mechanisms that enable cancer stem-like cells to escape cytotoxic treatment and repopulate the tumor. ...> Full Article

Newly discovered gene could be a prime target in the most lethal brain cancer (2/24/2009)

Scientists at Duke University Medical Center and Johns Hopkins University have discovered mutations in two genes that could become therapeutic targets in malignant glioma, a dangerous class of brain tumors. ...> Full Article

Gene may lead to early onset of brain tumor (1/29/2009)

People with a particular gene variant may be more likely to develop brain tumors, and at an earlier age, than people without the gene, according to a study published in the Jan. 27, 2009, print issue of Neurology, the medical journal of the American Academy of Neurology. ...> Full Article

New institute targets brain tumor removal (1/29/2009)

The Northwestern Brain Tumor Institute is a leader in the fight against brain and spinal tumors when it comes to clinical trial and treatment options. The Institute offers a multidisciplinary approach that involves state-of-the art technologies, a dynamic research program, and a wide range of treatment options in a supportive, compassionate environment. ...> Full Article

Researchers identify best treatments for long-term survival in brain tumor patients (12/10/2008)

Patients who had aggressive surgeries were free of tumor recurrence an average of 15 years after diagnosis ...> Full Article

Tiny sacs released by brain tumor cells carry information that may guide treatment (11/17/2008)

Exosomes deliver factors that promote tumor growth and may serve as blood biomarkers ...> Full Article

New approach to gene therapy may shrink brain tumors, prevent their spread (9/27/2008)

Animal study supports creating zone of resistance in surrounding normal tissue ...> Full Article

Methylation levels key to glioblastoma survival (9/26/2008)

A new study analyzing gene expression among patients with glioblastomas has found that not all of the common, deadly brain tumors appear the same upon closer examination. ...> Full Article

Family history of brain tumors linked to increased risk of brain cancer (9/23/2008)

People with a family history of cancerous brain tumors appear to be at higher risk of developing the same kind of tumors compared to people with no such family history ...> Full Article

Barrow researchers identify a new approach to detect the early progression of brain tumors (9/2/2008)

Study suggests a certain type of MRI scanning can detect when a patient is failing brain tumor treatment before symptoms appear. ...> Full Article

Childhood brain tumor traced to normal stem cells gone bad (8/12/2008)

An aggressive childhood brain tumor known as medulloblastoma originates in normal brain "stem" cells that turn malignant when acted on by a known mutant, cancer-causing oncogene ...> Full Article

Vaccine May Double Survival in Patients with Deadly Brain Tumors (6/4/2008)

A vaccine aimed at inducing immunity to the most common and deadly type of brain tumor may stave off recurrence and more than double survival in patients ...> Full Article

Too many gene copies stimulate tumor cell growth (4/11/2008)

New data has characterized a molecular pathway underlying low-grade forms of a type of brain tumor known as an astrocytoma ...> Full Article

New regulatory circuit identified for aggressive, malignant brain tumor (4/10/2008)

Research using a newly developed algorithm has significantly advanced understanding of the molecular events associated with the most common primary brain tumor in adults, human glioblastoma ...> Full Article

Human breast tumors' 'microenvironment' primes them for metastasis (4/7/2008)

The environment within primary breast tumors can 'empower' cells that break free and enter the bloodstream to successfully invade other organs ...> Full Article

New insight into the genetics of brain tumor formation (3/20/2008)

Researchers identify a potential new neuronal tumor suppressor ...> Full Article

Lab Engineers Virus That Can Kill Deadly Brain Tumors (2/23/2008)

A laboratory-engineered virus that can find its way through the vascular system and kill deadly brain tumors has been developed by Yale School of Medicine researchers, it was reported this week in the Journal of Neuroscience. ...> Full Article

New Brain Tumor Treatments Offer Hope (2/2/2008)

In 2008, approximately 215,000 Americans will be diagnosed with one of more than 100 types of brain tumors. Patients who receive such a diagnosis should remain hopeful, however, as treatment options at the nation's leading brain tumor centers have never been better, according to Philip Theodosopoulos, MD, assistant professor of neurosurgery and director of the division of skull base surgery at the University of Cincinnati (UC). ...> Full Article