Curing Death by Curing Aging Archives Page 69

When Tissue Repair Backfires (7/9/2007)

A new molecular link between inflammation and cancer, discovered through experiments with mice, has revealed how the body's natural repair response to tissue injury can actually spur tumor growth. ...> Full Article

Malaria-Resistant Mosquitoes Battle Disease With 'Molecular Warhead' (7/9/2007)

A team led by UT Southwestern Medical Center researchers has discovered why some mosquitoes are resistant to malaria, a finding that may one day help fight a disease that afflicts and kills millions of people. ...> Full Article

Scientists Work To Develop Simple Bladder Cancer Test (7/9/2007)

University of Florida researchers have identified a set of proteins that appear to signal the presence of bladder cancer, a discovery they hope will lead to a simple, fast and noninvasive test that can detect the disease early. ...> Full Article

First Baby Is Born After Oocytes Were Matured In The Lab And Frozen (7/8/2007)

The first baby to be created from an egg that had been matured in the laboratory, frozen, thawed and then fertilised, has been born in Canada. Three other women are pregnant by the same process. The research was presented to the 23rd annual meeting of the European Society of Human Reproduction and Embryology today (Monday 2 July). ...> Full Article

Scientists Discover Key to Manipulating Fat (7/8/2007)

In what they call a "stunning research advance," investigators at Georgetown University Medical Center have been able to use simple, non-toxic chemical injections to add and remove fat in targeted areas on the bodies of laboratory animals. They say the discovery, published online in Nature Medicine on July 1, could revolutionize human cosmetic and reconstructive plastic surgery and treatment of diseases associated with human obesity ...> Full Article

Gene Variations Directly Link Inflammation to an Increased Risk for Lung Cancer (7/8/2007)

Variations in two genes related to inflammation may be a major risk factor for developing lung cancer, according to a team of scientists from the National Cancer Institute and the University of Texas M. D. Anderson Cancer Center. The effect of these genes is especially strong among heavy smokers, suggesting that the inflammatory response is important in modulating the damage caused by tobacco smoke. ...> Full Article

Research Predicts HIV Drug Reaction (7/8/2007)

Specialists at Leicester's hospitals are taking part in research that is improving care for people living with HIV. ...> Full Article

Subset Of Dendritic Cells Could Be Used To Fight Infection (7/7/2007)

Although few people in the United States have reason to have heard of it, leishmaniasis is a parasitic disease that occurs in 88 different tropical and subtropical countries. Yet despite its prevalence, there is currently no vaccine to prevent transmission. Now, research by Rockefeller University scientists brings an effective vaccine one step closer, showing how it should be possible to recruit a specific subset of immune cells to do the lion's share of the work. ...> Full Article

Rethinking Therapeutic Cancer Vaccine Trials (7/7/2007)

Ongoing therapeutic cancer vaccine trials have yet to show evidence of vaccines spurring a patient's immune system to shrink tumors -- yet patients who receive these vaccines in trials tend to live longer and respond better to subsequent treatment. In the July 1 issue of Clinical Cancer Research, a journal of the American Association for Cancer Research, a team of National Cancer Institute researchers asks a fundamental question: are we looking at cancer vaccine trials the wrong way? ...> Full Article

Harnessing The Power Of The Immune System To Fight Cancer (7/7/2007)

Teaching the body's own immune system to seek out and destroy cancerous tumours represents a promising way to fight a disease that kills more than 70,000 Canadians a year. ...> Full Article

How a Genetic Roll of the Dice Paves the Way for Lymphatic Cancers (7/7/2007)

For most cells, keeping DNA in optimal condition is a high priority. Most cells do not hesitate to halt their usual life cycle while they fix anything that is amiss, even resorting to suicide to stop damage from spreading. But the immune system persistently gambles, putting organisms at risk for cancer and other diseases as it prepares to defend against potential pathogens. ...> Full Article

Extracting Eggs From Pre-pubertal Cancer Patients Brings Hope For Future Fertility (7/7/2007)

Scientists in Israel have been able to obtain and freeze eggs from the ovarian tissue of girls as young as 5 years old, the 23rd annual conference of the European Society of Human Reproduction and Embryology was told today (Tuesday 3 July). Dr. Ariel Revel, from the Department of Obstetrics and Gynaecology, Hadassah University Hospital, Jerusalem, Israel, said that the growing number of survivors of childhood cancers meant that such techniques would become increasingly important in preserving fertility in young patients. ...> Full Article

WFS1 Gene In More Common In People With Type 2 Diabetes (7/6/2007)

Researchers led by Cambridge scientists have defined a role for a gene called WFS1 in diabetes. Using their understanding of diabetes, they made educated choices about which genes might contribute. Their research, published in Nature Genetics today, hit gold with the revelation that a variant of WFS1 is more common in type 2 diabetes patients than in unaffected people ...> Full Article

Abnormal Insulin Test Levels Under Investigation (7/6/2007)

The patient safety team at the University of Chicago Medical Center is investigating two cases during May and early June in which blood tests showed insulin levels much higher than would normally be observed. Given these two instances and to ensure the highest level of patient safety, the Medical Center has notified appropriate regulatory, enforcement, and oversight agencies. ...> Full Article

Researchers Discover Method for Identifying How Cancer Evades the Immune System (7/6/2007)

One of the fundamental traits of a tumor - how it avoids the immune system - might become its greatest vulnerability, according to researchers from the University of Southern California. Their findings, demonstrated in human breast and colorectal cancers, indicate that a technique for determining a tumor's "immune signature," could be useful for diagnosing and treating specific cancers. ...> Full Article

Bed Nets May Be Key In Tackling Malaria (7/6/2007)

Protection using insecticide-treated bed nets may effectively combat malaria, research led by a Durham University expert has shown. ...> Full Article

How Cancer Evades the Immune System (7/5/2007)

USC researchers discover a way to determine which genes have been altered in a tumor, enabling it to avoid a body's defenses. ...> Full Article

Scientists Describe How 1918 Influenza Virus Sample was Exhumed in Alaska (7/5/2007)

The effort to find preserved samples of the 1918 influenza virus has been a pursuit of both historical and medical importance. The 1918 influenza pandemic was the most devastating single disease outbreak in modern history, and examining the virus that caused it may help prepare for, and possibly prevent, future pandemics. When the complete sequence of the 1918 virus was published in 2005, it represented a watershed event for influenza researchers worldwide. ...> Full Article

Possible Relation Between Dairy Consumption And Mutations Of A Gene That Causes Pancreatic Cancer Uab Barcelona (7/5/2007)

A scientific article published in the July issue of the English Journal of Epidemiology and Community Health suggests that there could be a relation between consuming dairy products and the mutations of a gene that is closely linked to pancreatic cancer. ...> Full Article

Turning Stem Cells Taken from Fat Tissue into Personalized, Cancer-Targeted Therapeutics (7/5/2007)

Researchers in Slovakia have been able to derive mesenchymal stem cells from human adipose, or fat, tissue and engineer them into "suicide genes" that seek out and destroy tumors like tiny homing missiles. This gene therapy approach is a novel way to attack small tumor metastases that evade current detection techniques and treatments, the researchers conclude in the July 1 issue of Cancer Research, a journal of the American Association for Cancer Research. ...> Full Article

Key To Male Infertility (7/5/2007)

A factor in immune cells regulates human semen and seems to determine whether a man will be fertile, according to a new study. ...> Full Article

More Couples Travel Abroad For Embryo Testing (7/4/2007)

A new study has shown that increasing numbers of couples are travelling abroad for embryo testing, known as preimplantation genetic diagnosis (PGD), and that the main reason for this cross-border movement is the legal position in patients' countries of origin. ...> Full Article

Natural Signal Holds Promise For Psoriasis, Age-Related Skin Damage (7/4/2007)

The body may hold a secret to normalizing skin cell growth that is over zealous in psoriasis and non-melanoma skin cancers and too slow in aging and sun-damaged skin, researchers say. ...> Full Article

Research Says Sugar Coated Proteins Seal in a Memory of Diabetes (7/4/2007)

Researchers at the University of Warwick's Warwick Medical School have uncovered a process that locks the body's metabolism in a diabetic state after only relatively limited exposure to high glucose levels. ...> Full Article

Human Antibodies that Block Human and Animal SARS Viruses Identified (7/4/2007)

An international team of investigators has identified the first human antibodies that can neutralize different strains of virus responsible for outbreaks of severe acute respiratory syndrome (SARS). The researchers used a mouse model and in vitro assays (lab tests) to test the neutralizing activity of the antibodies. The research team was led by scientists from the National Cancer Institute (NCI) and the National Institute of Allergy and Infectious Diseases (NIAID), both parts of the National Institutes of Health, and included collaborators from the U.S. Army (USAMRIID), academic institutions in the United States, Switzerland, and Australia. The research findings appear after July 2, 2007 in the early online edition of the Proceedings of the National Academy of Sciences. ...> Full Article

Loss Of Cell's 'Antenna' Linked To Cancer's Development (7/4/2007)

Submarines have periscopes. Insects have antennae. And increasingly, biologists are finding that most normal vertebrate cells have cilia, small hair-like structures that protrude like antennae into the surrounding environment to detect signals that control cell growth. In a new study published in the June 29 issue of Cell, Fox Chase Cancer Center researchers describe the strong link between ciliary signaling and cancer and identify the rogue engineers responsible for dismantling the cell's antenna. ...> Full Article

Critical Protein Prevents DNA Damage From Persisting Through Generations (7/3/2007)

A protein long known to be involved in protecting a cell from genetic damage has been found to play an even more important role in protecting the cell's offspring. New research shows that the protein, known as ATM, is not only vital for helping repair double-stranded breaks in the DNA of immune cells, but is also part of a system that prevents genetic damage from being passed on when the cells divide. ...> Full Article

'Modular' Leukemia Drug Shows Promise in Early Testing (7/3/2007)

A new type of engineered drug candidate has shown promise in treating chronic lymphocytic leukemia in both test tube and early animal tests, a new study shows. ...> Full Article

How Weight-Loss Prevents Breast Cancer Reoccurrence (7/3/2007)

Breast cancer is twice as likely to reoccur in women who are overweight or obese. Whether the process of weight loss provides protection against cancer, or if it is necessary to reach a healthy weight to reduce the reoccurrence of cancer is a key question addressed in a new study to be conducted by the Cancer Prevention Laboratory at Colorado State University. ...> Full Article

Gene Deficiency is a Protective Barrier to Obesity (7/2/2007)

A search for the molecular clues of longevity has taken Mayo Clinic researchers down another path that could explain why some people who consume excessive calories don't gain weight. The study, which was done in laboratory mouse models, points to the absence of a gene called CD38. When absent, the gene prevented mice on high-fat diets from gaining weight, but when present, the mice became obese. ...> Full Article