Curing Death by Curing Aging Archives Page 47

Therapeutic Targets in Multiple Myeloma (8/16/2007)

Researchers have identified molecular changes in multiple myeloma cells that activate an important biological pathway associated with cell growth and survival, thereby revealing potential new targets for drugs to treat this cancer. ...> Full Article

Promising New Nanomedical Cancer Therapy Also Highlights Tech Transfer, Inventor Says (8/16/2007)

If a new approach to cancer therapy, still experimental and in a phase I clinical trial, turns out as well as hoped, the credit will go as much to technology transfer as to scientific acumen. ...> Full Article

Study Begins to Reveal Clues to The Cause and Progression of Sepsis (8/16/2007)

Not all patients with sepsis mount the same immune response, even when they look the same clinically, according to findings from the first large-scale natural history study of sepsis. The results, published by University of Pittsburgh School of Medicine researchers in the August 13/27 issue of the Archives of Internal Medicine, indicate that past interpretations of how the immune system responds to infection - interpretations on which many experimental treatments were based - were incorrect. ...> Full Article

Major New Arthritis Study (8/16/2007)

More than 1,000 rheumatoid arthritis patients from West Yorkshire are to take part in a major new study which could lead to more effective targeting of treatment. ...> Full Article

Researchers Seek Volunteers For Study On Diabetes, Tuberculosis (8/16/2007)

A study at the Stanford University School of Medicine will investigate how diabetes increases a person’s vulnerability to infection with tuberculosis, or TB. Researchers are seeking participants for the study, which will look at type-2 diabetes and the body's immune response to the TB vaccine. ...> Full Article

New, Non-Surgical Technique Shown to Cure a Disabling and Potentially Fatal Ailment (8/16/2007)

Spine surgeon Paul Rubery, M.D., never imagined he would trade in his scalpel for Plaster of Paris, but that's exactly what he's planning to do in mid-August, when he learns a new, early treatment casting technique aimed at curing infants stricken with a devastating and aggressive form of scoliosis. ...> Full Article

Bursts of Waves Drive Immune System 'Soldiers' Toward Invaders (8/16/2007)

Scientists have discovered that torrents of microscopic waves propel white blood cells toward invading microbes. The discovery — recorded on videotape — holds the potential for better understanding and treatment of cancer and heart disease. ...> Full Article

Protein 'Chatter' Linked To Cancer Activation (8/15/2007)

Scientists have found the existence of cross-talk between human chromosome ends and the protein complexes central to the stability of the entire human genome, a "chat" that contributes to cancer development. ...> Full Article

Human stem cells help monkeys recover from Parkinson's (8/15/2007)

The same treatment might work in humans ...> Full Article

Pollution causes 40 percent of deaths (8/15/2007)

About 40 percent of deaths worldwide are caused by water, air and soil pollution, concludes a Cornell researcher. Such environmental degradation, coupled with the growth in world population, are major causes behind the rapid increase in human diseases, which the World Health Organization has recently reported. Both factors contribute to the malnourishment and disease susceptibility of 3.7 billion people, he says. ...> Full Article

Prostate Cancer Survival In Most Asian Men Better Than Predicted Using Conventional Prognosis Factors (8/15/2007)

Prognostic factors commonly used by clinicians to assess men with prostate cancer do not adequately predict survival outcomes in Asian men living in America, according to the first comprehensive ethnic analysis of Asian-American men with prostate cancer. ...> Full Article

Physicians Test New Device For Diagnosing And Treating Prostate Cancer (8/15/2007)

Samir Taneja, MD., Director of Urologic Oncology is the Primary Investigator on a clinical trial in order to test Envisioneering Technologies' new mechanical device called TargetScan, which preliminary tests indicate can improve doctors' ability to detect cancer and could lead to more targeted treatments—reducing life-altering side effects like impotence and incontinence. ...> Full Article

Multi-centre Study Proves a New Treatment Option for Asian Chronic Hepatitis C Patients (8/15/2007)

Chronic hepatitis C is an important cause of liver cirrhosis and liver cancer. According to the 2005 updated report by the Department of Health, approximately 10% of people with history of blood transfusion and over 50% of intravenous drug abusers in Hong Kong are infected by hepatitis C virus. ...> Full Article

Physician-scientists pinpoint how cancer spreads within the brain (8/15/2007)

Team finds "switch" that sparks cancer cells to travel ...> Full Article

Protein Plays Role in Increased Skin Pigmentation (8/14/2007)

Researchers have identified a protein that plays an important, early role in the increase of protective skin pigmentation after exposure to ultraviolet (UV) radiation. The protein, called SOX9, is a transcription factor known to participate in embryo development and to be expressed in many adult tissues including the heart, kidney, and brain. ...> Full Article

Newly Created Cancer Stem Cells Could Aid Breast Cancer Research (8/14/2007)

In some ways, certain tumors resemble bee colonies, says pathologist Tan Ince. Each cancer cell in the tumor plays a specific role, and just a fraction of the cells serve as "queens," possessing the unique ability to maintain themselves in an unspecialized state and seed new tumors. These cells can also divide and produce the "worker" cells that form the bulk of the tumor. ...> Full Article

E. coli bacteria linked to Crohn's disease (8/14/2007)

A team of Cornell scientists has discovered that intestinal inflammation in patients with Crohn's disease may be associated with a novel group of E. coli bacteria with genes similar to bacteria that cause diseases ranging from salmonella to cholera and even bubonic plague. ...> Full Article

MicroRNA 'sponges' could aid cancer studies (8/14/2007)

MIT researchers have developed a new way to study the function of microRNA, tiny strands of genetic material that help regulate at least 25 percent of a cell's genes. ...> Full Article

Study Suggests Loss of Two Types of Neurons-Not Just One-Triggers Parkinson's (8/14/2007)

New evidence indicates that the loss of two types of brain cells--not just one as previously thought--may trigger the onset of symptoms associated with Parkinson's disease. ...> Full Article

Researchers Find Diabetes Drug Kills Some Cancer Cells (8/14/2007)

Researchers at the University of Pennsylvania School of Medicine have found that a commonly prescribed diabetes drug kills tumor cells that lack a key regulatory gene called p53. ...> Full Article

Survival Differences By Race Most Apparent In Advanced Stages Of Breast Cancer (8/14/2007)

Racial differences in breast cancer survival increase according to stage of disease, a new study finds. ...> Full Article

No Evidence That Widely Prescribed Statins Protect Against Prostate Cancer (8/13/2007)

A large community-based study refutes previous findings that statins - a top-selling drug class, worldwide -- might cut one's risk of developing prostate cancer by reducing production of the male hormones that fuel cancer growth. ...> Full Article

Smokeless Tobacco More Effective than Cigarettes for Delivering Dangerous Carcinogens into the Body (8/13/2007)

It may not be inhaled into the lungs, but smokeless tobacco exposes users to some of the same potent carcinogens as cigarettes. In the August issue of Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research, researchers at the University of Minnesota Cancer Center report that users of smokeless tobacco are exposed to higher amounts of tobacco-specific nitrosamines -- molecules that are known to be carcinogenic -- than smokers. ...> Full Article

New Cause of Tamoxifen Resistance in Breast Cancer (8/13/2007)

When a woman receives a breast cancer diagnosis her entire life may change in the blink of an eye. But the nature of that change is governed by the smallest alterations that take place within the proteins of the tumor cells, determining what treatments she can pursue with a hope of cure and those to which her cancer is resistant. ...> Full Article

Do Bones Help Control Metabolism and Weight? (8/13/2007)

Osteocalcin Finding May Implicate Bone as Therapeutic Target for Type 2 Diabetes ...> Full Article

Researchers Discover Novel Pathway for Increasing 'Good' Cholesterol (8/12/2007)

Researchers at the University of Pennsylvania School of Medicine have discovered that a group of liver enzymes called proprotein convertases (PCs) may be the key to raising levels of good cholesterol (HDL-C). ...> Full Article

Scientist aims to stop cancer cells reading their own DNA (8/12/2007)

A promising new line in anti-cancer therapy by blocking the molecular motors involved in copying genetic information during cell division is being pursued by young Dutch researcher Dr. Nynke Dekker in one of this year's EURYI award winning projects sponsored by the European Science Foundation (ESF) and the European Heads of Research Councils (EuroHORCS). Dekker and her team are trying to stop tumor development by interfering with the molecular motors that copy DNA during cell division. This will cut off the genetic information flow that tumours need to grow, and could complement existing cancer therapies, while in the longer term bringing the promise of improved outcomes with greatly reduced side effects. ...> Full Article

Light Shines Way To Early Detection Of Oral Cancer (8/12/2007)

A light being trialed by University of Queensland researchers is showing promise as a tool for early detection of oral cancer - one of the deadliest cancers. ...> Full Article

Scientists Discover A Control Mechanism For Metastasis (8/12/2007)

Metastasis - when cancer cells dissociate from the original tumor and migrate via the blood stream to colonize distant organs - is the main cause of cancer death. A team of scientists at the Weizmann Institute of Science has now revealed new details about the mechanisms controlling metastasis of breast cancer cells. Their findings, published recently online in Nature Cell Biology, add significantly to the understanding of metastasis and may aid, in the future, in the development of anti-cancer drugs. ...> Full Article

Study Finds Pro-Death Proteins Required to Regulate Healthy Immune Function (8/11/2007)

Researchers at the University of Pennsylvania School of Medicine have found that proteins known to promote cell death are also necessary for the maturation and proliferation of immune cells. Activation of T-cell receptors on the surface of lymphocytes by foreign antigens initiate a calcium-mediated signaling pathway that ends in cell differentiation and growth. The Penn scientists discovered that in the cells that lack the pro-death proteins Bax and Bak, calcium signaling is disrupted and energy production is reduced. Restoration of Bax corrects the signaling problems, increases energy production, and stimulates cell division. ...> Full Article