Curing Death by Curing Aging Archives Page 34

Gene Expression Profiling Advance for Lung Cancer Prognosis (2/20/2008)

Researchers ID two signatures predicting survival ...> Full Article

The missing link (2/20/2008)

Researchers home in on the connection between obesity and insulin resistance ...> Full Article

'Invisible' bacteria dupe the human immune system (2/20/2008)

Scientists at the University of York have characterised an important new step in the mechanism used by bacteria to evade our immune system. ...> Full Article

Expert Adds Obesity to Side Effects of Lead Exposure (2/19/2008)

Optometry professor finds unexpected link between prenatal lead exposure and obesity in males ...> Full Article

Defining Cance's Genetic 'Support Network' (2/19/2008)

Genomic researchers use new statistical techniques to look for relationships among sets of genes ...> Full Article

Seeing small, thinking big (2/19/2008)

Microbiologist Marc Jenkins is tracking the movements of immune system cells with an eye to developing vaccines, preventing organ transplant rejection and combating autoimmune diseases. Cell biologist Mary Porter is studying the molecular motors that move substances along the highways within cells, a function critical to development and function of organs and even entire organisms. Timothy Ebner, professor and head of neuroscience, is studying how brain circuits work in the areas of the brain that control movements, and how these circuits malfunction in neurological disease. ...> Full Article

Increased Life Expectancy May Mean Lower Fertility (2/19/2008)

One of the benefits of postindustrial life is that it is largely free of the fear of early mortality. However, a curious side-effect of this confidence seems to be a dramatic reduction in birthrates. Writing in the journal Science, Professor Ruth Mace (UCL Anthropology) draws a clear correlation between increased life expectancy and lower fertility in cities. ...> Full Article

Mesothelin engineered on virus-like particles provides treatment clues for pancreatic cancer (2/19/2008)

New understanding of a protein that spurs the growth of pancreatic cancer could lead to a new vaccine against the deadly disease, said researchers at Baylor College of Medicine in Houston in a report appearing in the current edition of the journal Molecular Cancer Therapeutics. ...> Full Article

Scientists Using Laser Light To Detect Potential Diseases Via Breath, Says Study (2/19/2008)

By blasting a person's breath with laser light, scientists from the National Institute of Standards and Technology and the University of Colorado at Boulder have shown that they can detect molecules that may be markers for diseases like asthma or cancer. ...> Full Article

Researchers add further weight to link between cancer and obesity (2/18/2008)

Researchers from the University of Manchester, Christie Hospital and University of Bern in Switzerland have today published findings in the Lancet medical journal which further support the link between obesity and risk of developing cancer. ...> Full Article

Hispanics Have More Difficulty Controlling Diabetes than Non-Hispanic Whites (2/18/2008)

Results of an analysis of multiple studies show diabetes control is more challenging for Hispanics than non-Hispanic whites, according to researchers at Wake Forest University Baptist Medical Center and colleagues. ...> Full Article

Scientists develop tool to probe role of oxidative stress in aging, disease (2/18/2008)

Oxygen, although essential for human life, can turn into an aggressive chemical that is outright toxic to important molecules inside our cells. This "oxidative stress" is associated with many diseases, such as Alzheimer's, heart disease and cancer, and has been suggested to be the culprit underlying aging. ...> Full Article

Antibody Can Potently Neutralize Two Viruses (2/18/2008)

In laboratory experiments, scientists at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH), and their colleagues supported by the NIH National Institute of Allergy and Infectious Disease (NIAID), have discovered an antibody that neutralizes two viruses classified as henipaviruses. Nipah virus (NiV) and Hendra virus (HeV) are highly infectious agents that transitioned from infecting flying foxes in the mid-1990s to causing fatal disease in humans and livestock in Australia, Bangladesh, India, Malaysia, and Singapore. Recent outbreaks have resulted in encephalitis and acute respiratory distress, person-to-person transmission, and up to 70 percent fatality rates. The finding appears in the Feb. 15, 2008, issue of The Journal of Infectious Diseases. ...> Full Article

Mitochondrial DNA mutations can cause degenerative heart and muscle disease (2/17/2008)

Study provides insights into age-related diseases and proof that mitochondrial DNA is central to health ...> Full Article

Scientists Confirm Discovery of New Virus Responsible For Deaths of 3 Transplant Recipients From Single Donor in Victoria, Australia (2/17/2008)

Establishes high throughput genetic sequencing as powerful tool for pathogen discovery; technology enables improvements in screening for transplant safety ...> Full Article

Genetic breakthrough supercharges immunity to flu and other viruses (2/17/2008)

Researchers discover way to boost cells' natural anti-virus defences ...> Full Article

HIV Persists in the Gut Despite Long-Term HIV Therapy--Second Study Finds that B-Cell Abnormalities Also Persist (2/17/2008)

Second Study Finds that B-Cell Abnormalities Also Persist ...> Full Article

New picture of HIV-1's protein jacket identifies attractive target for antibody-based vaccine (2/16/2008)

By coaxing the HIV-1 protein to reveal a hidden portion of its protein coat, scientists at Dana-Farber Cancer Institute and Harvard Medical School have provided a newly detailed picture of how protective, or so-called broadly neutralizing, antibodies block HIV-1 infection. ...> Full Article

Researchers discover new compounds active against tuberculosis and malaria (2/16/2008)

Researcher has discovered new compounds active for treating tuberculosis and malaria. Her thesis, defended at the School of Sciences, describes the synthesis and characterisation of 65 derivatives of quinoxaline, the structure of which is similar to a number of antimalalarial and antituberculosis pharmaceutical drugs currently on the market. Of the molecules prepared, four stand out for their antimalalarial activity and 15 for their antituberculosis activity. ...> Full Article

Research Team Identifies Novel Anti-Cancer Drug from the Sea (2/16/2008)

A collaborative team of researchers spearheaded by Dennis Carson, M.D., professor of medicine and director of the Rebecca and John Moores UCSD Cancer Center at the University of California, San Diego (UCSD) has identified a potent new anti-cancer drug isolated from a toxic blue-green algae found in the South Pacific. The properties of somocystinamide A (ScA) are described in a paper that will be published online in Proceedings of the National Academy of Science the week of February 11 -15. ...> Full Article

Brain Damage Occurs Within Minutes from the Onset of a Stroke, Study Reveals (2/15/2008)

Scientists at the Brain Research Centre at the University of British Columbia and Vancouver Coastal Health Research Institute have found that harmful changes to the brain's synaptic connections occur within the first three minutes following a stroke. ...> Full Article

Mutant parasites offer researchers hope in fight against malaria (2/15/2008)

Parasites that cause malaria and other significant diseases are clever squatters that lurk in the body, waiting for an opportune time to assert themselves, scientists have learned. They survive by finding the right place to hide, stealing food from their hosts and evading the body's immune system. ...> Full Article

New approach may render disease-causing staph harmless (2/15/2008)

Researchers at the University of Illinois helped lead a collaborative effort to uncover a completely new treatment strategy for serious Staphylococcus aureus ("Staph") infections. The research, published Feb. 14 in ScienceXpress, the online version of Science magazine, comes at a time when strains of antibiotic-resistant Staph (known as MRSA, for methicillin-resistant S. aureus) are spreading in epidemic proportions in hospital and community settings. ...> Full Article

New findings for breast cancer survivors (2/15/2008)

New findings from a clinical trial coordinated at Queen's University show that women who survive breast cancer - the most common form of cancer among Canadian women - are more likely to die from other causes. The results were particularly striking for older women. ...> Full Article

New Trial to Test Radiation-Emitting Beads Against Advanced Liver Cancer (2/15/2008)

Liver cancer specialists at Jefferson's Kimmel Cancer Center in Philadelphia are beginning an 18-month study of a new treatment for liver cancer. The therapy entails injecting tiny beads that emit small amounts of radiation into the liver's main artery while also blocking the blood supply feeding the cancer's growth. ...> Full Article

Yale Test Detects Early Stage Ovarian Cancer With 99 Percent Accuracy (2/14/2008)

Researchers at Yale School of Medicine have developed a blood test with enough sensitivity and specificity to detect early stage ovarian cancer with 99 percent accuracy. ...> Full Article

Bacterial Toxin Closes Gate on Immune Response, Researchers Discover (2/14/2008)

Implications for Finding New Ways to Fight MRSA ...> Full Article

New company Inspiralis to search for cancer drugs and antibiotics (2/14/2008)

A new company has joined the fight against MRSA and cancer. Researchers at the John Innes Centre (Norwich) have launched a new company, Inspiralis Ltd, based around their expertise in DNA topoisomerases - a group of enzymes that help DNA molecules to unravel and wind up properly and not to become tangled during replication. ...> Full Article

Experimental HIV vaccine gets a boost from '70s-era discovery (2/14/2008)

Although science is known for being a forward-looking field, researchers have found that they can often benefit from a glance over their shoulders. By combining an experimental AIDS vaccine with a long-neglected molecule called poly-IC, Rockefeller University scientists discovered that they were able to significantly improve its effectiveness. Their new, bolstered vaccine not only stimulated the production of HIV-attacking immune cells in mice, but also allowed the rodents to maintain immunity over a significantly longer period of time. ...> Full Article

Gene Therapy Protocol Activates Immune System in Patients with Leukemia (2/13/2008)

A research team at the Rebecca and John Moores UCSD Cancer Center at University of California, San Diego (UCSD) reports that patients with chronic lymphocytic leukemia (CLL) who were treated with a gene therapy protocol began making antibodies that reacted against their own leukemia cells. The study will be published on line the week of February 11-15 in the online edition of the Proceedings of the National Academy of Science. ...> Full Article