Curing Death by Curing Aging Archives Page 15

Novel Discovery by Scientists Could Lead to Much-Needed Treatment for Kidney Failure (3/17/2008)

The unwanted activation of an important cell-signaling pathway may play a role in two kidney problems that are major causes of end-stage renal disease, scientists at the Albert Einstein College of Medicine of Yeshiva University have found. Their research, which opens up a novel approach for treating kidney failure, is described in the March issue of Nature Medicine. ...> Full Article

Researchers initiate phase I diabetes trial (3/17/2008)

Scientists at the Massachusetts General Hospital (MGH) have initiated a phase 1 clinical trial to reverse type 1 diabetes. The trial is exploring whether the promising results from the laboratory of Denise Faustman, MD, PhD, can be applied in human diabetes. Faustman's previous studies have shown that mice with a form of diabetes that closely resembles type 1 diabetes in humans can be cured. In the animal studies, a commonly used vaccine that provides protection against tuberculosis, called Bacillus Calmette-Guerin (BCG) was used effectively to deplete the abnormal immune cells that attack and destroy the insulin producing cells of the pancreas. The first step in the human study, which is currently enrolling volunteers, is to determine whether the same strategy using BCG vaccination can be used to modify the abnormal autoimmune cells that are present in type 1 diabetes, sometimes called "juvenile-onset" diabetes. ...> Full Article

Scientists discover how TB 'develops invincibility' against only available treatment (3/17/2008)

Scientists have uncovered a dramatic new twist in the battle against TB ...> Full Article

Gene Hunters Fine-Tune Marker for Common Obesity Gene (3/17/2008)

In Children's DNA, a Hint of a Mutation's Ancestral African Origin ...> Full Article

Specialized natural killer cells in human tonsils pack a punch (3/16/2008)

Tonsils are a source of sore throats and an excuse for ice cream. But they also provide an important protective service, their immune-cell-rich tissue acting as the body's first defense against the germs about to be swallowed or inhaled. Researchers have known that tonsils are packed with B cells, which flag invaders for other cells to attack. But a new study by Rockefeller University scientists shows that tonsils also house a different, very specialized cell that helps protect against the Epstein Barr virus (EBV). ...> Full Article

Is increased Slug expression associated with the progression to esophageal cancer? (3/16/2008)

Real-time reverse transcription-polymerase chain reaction (RT-PCR), semi-quantitative immunohistochemistry and tissue array reveal that the progression to adenocarcinoma is associated with increased Slug expression and this may represent a mechanism of E-cadherin silencing ...> Full Article

New technique takes a big step in examination of small structures (3/16/2008)

A team led by a Purdue University researcher has achieved images of a virus in detail two times greater than had previously been achieved ...> Full Article

A tumor of the pancreas mimicked by colonic duplication? (3/16/2008)

A case of cystic colonic duplication in an adult mimicked a tumor of the pancreas and the diagnosis was established by histopathological examination of the resected specimen after distal pancreatectomy. ...> Full Article

Soy compound may halt spread of prostate cancer (3/16/2008)

A compound found in soybeans almost completely prevented the spread of human prostate cancer in mice ...> Full Article

Ibuprofen Destroys Aspirin's Positive Effect on Stroke Risk (3/15/2008)

Stroke patients who use ibuprofen for arthritis pain or other conditions while taking aspirin to reduce the risk of a second stroke undermine aspirin's ability to act as an anti-platelet agent, researchers at the University at Buffalo have shown. ...> Full Article

New chemical can kill latent tuberculosis bacteria (3/15/2008)

Eliminating this dormant but threatening form of the bacteria could prevent TB's spread, Weill Cornell researchers say ...> Full Article

A protein that triggers aggressive breast cancer (3/15/2008)

SATB1 is a nuclear protein well known for its crucial role in regulating gene expression during the differentiation and activation of T cells, making it a key player in the immune system. But SATB1 has now revealed a darker side: it is an essential contributing factor in the most aggressive forms of breast cancer. ...> Full Article

Study helps explain fundamental process of tumor growth (3/15/2008)

Unique metabolic process first identified eight decades ago is found to be key ...> Full Article

Research could put penicillin back in battle against antibiotic resistant bugs that kill millions (3/15/2008)

Research led by the University of Warwick has uncovered exactly how the bacterium Streptococcus pneumoniae has become resistant to the antibiotic penicillin. The same research could also open up MRSA to attack by penicillin and help create a library of designer antibiotics to use against a range of other dangerous bacteria. ...> Full Article

Mouse model for mesothelioma reproduces human disease (3/14/2008)

Scientists have established a mouse model for human malignant mesothelioma (MM) that will provide valuable insight into cancer development and progression along with new directions for design of therapeutic strategies. The research, published by Cell Press in the March issue of Cancer Cell, may eventually lead to a substantially improved outlook for patients with this devastating disease. ...> Full Article

Researchers Highlight Anti-Cancer Benefits of Vitamin D (3/14/2008)

Vitamin D has long been recognized for its role in making healthy bones, but a growing body of evidence now suggests that it can also significantly reduce the risk of developing several types of cancers. ...> Full Article

Inhaled tuberculosis vaccine more effective than traditional shot (3/14/2008)

A novel aerosol version of the most common tuberculosis (TB) vaccine, administered directly to the lungs as an oral mist, offers significantly better protection against the disease in experimental animals than a comparable dose of the traditional injected vaccine, researchers report this week in the Proceedings of the National Academy of Sciences. ...> Full Article

Researchers develop a method to select eggs with the best chance of leading to successful pregnancy (3/14/2008)

A research team supervised by Université Laval scientist Marc-André Sirard has identified genetic markers that allow the selection of eggs with the best chance of leading to successful pregnancy after in vitro fertilization (IVF). This finding could both increase the success rate of single embryo transfer and diminish the risk of multiple pregnancies. The details of the method developed by the researchers, for which an international patent application has been filed, are explained on the website of the scientific journal Human Reproduction. ...> Full Article

Is a cup of tea really the answer to everything - even anthrax? (3/14/2008)

A cup of black tea could be the next line of defense in the threat of bio-terrorism according to new international research ...> Full Article

Post-stroke clot-busting therapy beneficial for patients on aspirin (3/13/2008)

Patients given a clot-busting drug following stroke appear to have better outcomes if they were already taking anti-platelet medications, despite an apparent increased risk for bleeding in the brain. ...> Full Article

Researchers ID behavioral risk factors for head and neck cancers (3/13/2008)

Sex practices and lifestyle are culprits ...> Full Article

Screening For Mrsa At Hospital Admission Not Associated With Reduced Rates Of Infection In Surgical Patients (3/13/2008)

New findings do not support the recommendation for universal screening on hospital admission for methicillin-resistant Staphylococcus aureus (MRSA) to reduce the rate of hospital-acquired infections in surgical patients ...> Full Article

Magnesium associated with lower risk for some strokes in male smokers (3/12/2008)

Male smokers who consume more magnesium appear to have a lower risk for cerebral infarction, a type of stroke that occurs when blood flow to the brain is blocked, according to a report in the March 10 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. ...> Full Article

Recurrent Low-Grade Carcinoma of the Ovary Less Responsive to Chemotherapy Than More Common Ovarian Cancers (3/12/2008)

The retrospective study is the first to analyze how women with low-grade tumors respond to chemotherapy in recurrent setting and confirms clinical impressions that the tumors are chemoresistant, said lead author David M. Gershenson, M.D., professor and chair of the Department of Gynecologic Oncology at M. D. Anderson. Previous studies have shown similar tumor resistance in newly diagnosed patients, and there is currently no standard of care for women facing the disease. ...> Full Article

Pandemic flu may be well mitigated until a vaccine is available (3/12/2008)

Researchers model flu to help guide national pandemic planning ...> Full Article

Researchers demonstrate protective role of microRNA (3/11/2008)

Genetic snippets linked to cancer also key to embryonic cell development ...> Full Article

Research Reveals How Food Poisoning and Bioterrorism Toxins Could Be Tamed (3/11/2008)

New insights into how plant toxin ricin kills cells could help scientists develop drugs to counteract poisonings ...> Full Article

Researchers identify colorectal cancer gene (3/11/2008)

Study is a step towards the future of genetic testing for the third most commonly diagnosed cancer in Americans ...> Full Article

Einstein researchers discover gene mutations linked to longer lifespans (3/10/2008)

Mutations in genes governing an important cell-signaling pathway influence human longevity, scientists at the Albert Einstein College of Medicine of Yeshiva University have found. ...> Full Article

Low micro-RNA Level Linked to High Gene Activity in AML (3/10/2008)

A new study suggests that a type of acute leukemia may occur in part because abnormally low levels of one small molecule result in the over-activity of genes important to the disease. ...> Full Article