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Curing Death by Curing Aging - December 2007 ArchivesTwo Genes Are Important Key to Regulating Immune Response (12/31/2007)Pbx-1, Prep-1 Help Spur IL-10 Production; Findings Have Implications for Research into Lupus, Cancer and HIV/AIDS ...> Full Article Researchers Hot on the TRAIL of New Cancer Targets (12/30/2007)Cell-Death Receptor Link Between Cancer Susceptibility and Inflammation ...> Full Article New Drug Targets May Fight Tuberculosis and Other Bacterial Infections in Novel Way (12/29/2007)Research Into 'Virulence Factors' Expands War Against Infectious Disease Beyond Antibiotics ...> Full Article New Ingredients in Drug-Like Anti-Aging Products Improve Skin (12/29/2007)Cosmecueticals, beauty aids that reportedly work like prescription drugs, are providing new ways to treat aging skin. A study recently published in the Journal of Cosmetic Dermatology explores a variety of new ingredients in cosmeceuticals that provide a visibly noticeable improvement in maturing skin. ...> Full Article Breast cancer gene mutation more common in Hispanic, young black women (12/28/2007)A genetic mutation already known to be more common in Ashkenazi Jewish breast cancer patients is also prevalent in Hispanic and young African-American women with breast cancer, according to one of the largest, multiracial studies of the mutation to date. ...> Full Article Biomarker could lead to new treatment for cancer and Crohn's disease (12/28/2007)Cambridge Enterprise Limited, the commercialisation office of the University of Cambridge, has completed a licence agreement with Medarex, Inc. for the potential development of a therapeutic drug to treat cancer and autoimmune diseases. ...> Full Article Sea cucumber protein used to inhibit development of malaria parasite (12/27/2007)Scientists have genetically engineered a mosquito to release a sea-cucumber protein into its gut which impairs the development of malaria parasites, according to research out today (21 December) in PLoS Pathogens. Researchers say this development is a step towards developing future methods of preventing the transmission of malaria. ...> Full Article New Research Tools Suggest Cancer And Other Diseases Are Too Complex For Easy Answers, Researchers Say (12/27/2007)Scientists who study cancer may be prone to drawing simplistic conclusions from the powerful molecular tools now available because they don't appreciate how complex the data is that is being generated, said a team of Georgetown University Medical Center (GUMC) researchers in the January issue of Nature Reviews Cancer. ...> Full Article New thermal-imaging technique may help victims of head and neck cancers (12/27/2007)
Researchers Initiate Gene Therapy Trial in Patients with Advanced Skin Cancer (12/26/2007)Researchers at the Ireland Cancer Center of University Hospitals Case Medical Center are the first in the region to have joined a nationwide clinical trial to evaluate the effectiveness of a gene therapy in patients with advanced melanoma which is aimed to help a patient's own immune system fight their cancer. ...> Full Article Light powered platinum more targeted and 80 times more powerful than similar cancer treatments (12/25/2007)Researchers have discovered a new light-activated platinum-based compound that is up to 80 times more powerful than other platinum-based anti-cancer drugs and which can use "light activation" to kill cancer cells in much more targeted way than similar treatments. ...> Full Article First Look at an Enzyme Target for Antibacterial and Cancer Drugs (12/25/2007)
Scientists develop new drug candidate to outflank cancer resistance (12/25/2007)A new drug candidate first synthesized by scientists in the Medicinal Chemistry Group at the University of Bath has shown promising experimental results against breast and prostate cancer cells and tumours that are resistant to conventional hormone-based treatments. ...> Full Article Cancer Stem Cells: Know Thine Enemy (12/24/2007)Stem cells-popularly known as a source of biological rejuvenation-may play harmful roles in the body, specifically in the growth and spread of cancer. Amongst the wildly dividing cells of a tumor, scientists have located cancer stem cells. Physician-scientists from Weill Cornell Medical College are studying these cells with hopes of combating malignant cancers in the brain. ...> Full Article Aging Gracefully Requires Taking Out The Trash (12/24/2007)Suppressing a cellular cleanup-mechanism known as autophagy can accelerate the accumulation of protein aggregates that leads to neural degeneration. In an upcoming issue of Autophagy, scientists at the Salk Institute for Biological Studies report for the first time that the opposite is true as well: Boosting autophagy in the nervous system of fruit flies prevented the age-dependent accumulation of cellular damage in neurons and promoted longevity. ...> Full Article Researchers find link between cellular defense processes, showing how cancer cells survive (12/24/2007)investigators have discovered that immune system cells that engulf and destroy germs in the body enlist help for this task from a common housekeeping mechanism that most cells use to keep their interiors healthy, a finding that is likely to help researchers understand how the body defends itself against infections and how cancer cells can resist chemotherapy drugs before they have a chance to work. ...> Full Article New insights into deadly heart rhythm disorder (12/23/2007)Better ways to identify people at risk for ventricular fibrillation could arise from U-M/SUNY group's work showing universal law of electrical turbulence in the heart ...> Full Article Microchip-based device can detect rare tumor cells in bloodstream (12/23/2007)Blood 'biopsy' may provide information to guide treatment planning, monitor response ...> Full Article High-Fat, High-Carb Meal More Destructive to the Obese (12/23/2007)Increase in already high free radicals significantly raises heart-attack risk ...> Full Article Studies New Treatment for Advanced Melanoma (12/22/2007)researchers are evaluating the safety and effectiveness of Allovectin-7, an investigational treatment for advanced melanoma. ...> Full Article Heart Attack Risk From Smoking Due to Genetics (12/22/2007)Heart attacks among cigarette smokers may have less to do with tobacco than genetics. ...> Full Article Attention Guys - Testicular Cancer Isn't as Rare as You Think (12/22/2007)Paying closer attention to the look and feel of your testicles could be a lifesaver. ...> Full Article Researcher helping Estonia develop system for HIV/AIDS (12/22/2007)A researcher has received a grant from Estonia to develop a program to understand its burgeoning number of HIV/AIDS cases. ...> Full Article Researchers reveal missing link in a heart disease pathway (12/22/2007)Scientists have helped characterize a previously unknown link in the chain of biochemical reactions implicated in some forms of heart disease. ...> Full Article Team Finds a Widely Used Anti-Malarial Drug Prevents Cancer Development (12/22/2007)Study Offers Proof of Principle for Novel Anti-Tumor Therapy ...> Full Article Why don't we get cancer all the time? (12/21/2007)The seemingly inefficient way our bodies replace worn-out cells is a defense against cancer, according to new research. ...> Full Article Scientists Report Ability to Identify and Repress Breast Cancer Stem Cells in Mouse Tissue (12/21/2007)An approach based on the manipulation of microRNAs ...> Full Article National study looks at genetics of COPD (12/21/2007)The identification of genes and other risk factors that influence the development of chronic obstructive pulmonary disease or COPD are under study at Baylor College of Medicine and the Michael E. DeBakey Veterans Affairs Medical Center. ...> Full Article Mutant Gene Identified as Villain in Hardening of the Arteries (12/20/2007)A genetic mutation expands lesions in the aorta and promotes coronary atherosclerosis, more commonly known as hardening of the arteries, according to a study by Yale School of Medicine in Cell Metabolism. ...> Full Article Researchers Train the Immune System to Deliver Virus that Destroys Cancer in Lab Models (12/20/2007)An international team of researchers led by Mayo Clinic have designed a technique that uses the body's own cells and a virus to destroy cancer cells that spread from primary tumors to other parts of the body through the lymphatic system. In addition, their study shows that this technology could be the basis for a new cancer vaccine to prevent cancer recurrence. ...> Full Article Firefly genes allow testing of new therapy against lymphoma (12/20/2007)Researchers here have figured out a way to use a firefly gene to let them see just how effective a new drug combination actually is against some forms of cancer and its serious complication. ...> Full Article Molecular 'trip switch' shuts down inflammatory response (12/19/2007)Like a circuit breaker that prevents electrical wiring from overheating and bringing down the house, a tiny family of three molecules stops the immune system from mounting an out-of-control, destructive inflammatory response against invading pathogens, researchers at the Salk Institute for Biological Studies have found. ...> Full Article Cancer and Arthritis Therapy May Be Promising Treatment for Diabetes (12/19/2007)An antibody used to treat certain cancers and rheumatoid arthritis appears to greatly delay type 1 diabetes in mice, Yale School of Medicine researchers report in the Journal of Clinical Investigation. ...> Full Article Drug combination shrinks breast cancer metastases in brain (12/19/2007)A combination of a "targeted" therapy and chemotherapy shrank metastatic brain tumors by at least 50 percent in one-fifth of patients with aggressive HER2-positive breast cancer, according to data presented by Dana-Farber Cancer Institute investigators at the San Antonio Breast Cancer Symposium. ...> Full Article Even Tiny Breast Tumors Can Be Aggressive and May Require Maximum Therapy (12/19/2007)Breast tumors that are 1 centimeter in size or smaller - no more than 0.4 inch in length - can still be very aggressive and may require more intensive therapy than is routinely offered today, say researchers at Mayo Clinic in Jacksonville, Fla. ...> Full Article Do everyday foods influence risk of prostate cancer? (12/19/2007)The biggest ever study on the effect of folate and vitamin B12 on prostate cancer is set to go ahead at Bristol University after World Cancer Research Fund (WCRF) announced it would fund the project. ...> Full Article High-Dose Chemotherapy, Autologous Stem Cell Transplantation Shows Little or No Survival Benefit as Adjuvant Therapy for Node-Positive Breast Cancer (12/18/2007)Definitive Study Reviewed 15 Randomized Studies of Controversial Treatment ...> Full Article Crawling Worms May Illuminate Dopamine's Role in Human Aging Diseases (12/18/2007)Research carried out with a paintbrush bristle, a metronome, smelly chemicals and thousands of microscopic worms called nematodes may reveal important information about human aging diseases like Parkinson's and Alzheimer's, thanks to a grant from the Ellison Medical Foundation awarded to a University at Buffalo neurobiologist. ...> Full Article Researchers nix low-carb diet (12/18/2007)For most of the past decade, there was much hubbub about the Atkins and Zone diets. Both focus on quick, effective ways to lose weight through high-protein and low-carbohydrate foods. Today, many still swear by them. ...> Full Article Can interacting pathogens explain disease patterns? (12/18/2007)The way in which parasites interact with each other could help predict more successfully when infectious cyclical diseases in humans are likely to occur, according to a new collaborative study. ...> Full Article Genetic Causes for Male Infertility Studied (12/18/2007)
Abdominal fat distribution predicts heart disease (12/18/2007)Abdominal obesity is a strong independent risk factor for heart disease, and using the waist-hip ratio rather than waist measurement alone is a better predictor of heart disease risk among men and women, researchers reported in a study published in Circulation: Journal of the American Heart Association. ...> Full Article Space-tech could make life easier for diabetics (12/17/2007)
Researchers Discover Virus Using Same Tools as Host Cell (12/17/2007)Duke University Medical Center researchers have discovered that the virus which causes Kaposi's Sarcoma encodes a molecule for controlling gene regulation nearly identical to one found normally in human cells. Both versions of the molecule, known as a microRNA, appear to play a role in the development of cancer. ...> Full Article Bringing Viruses Back to Life (12/17/2007)It's a prospect that may unnerve some-scientists bringing extinct viruses back to life to learn more about how they evolved along with humans. But when it comes to retroviruses like HIV, which take up permanent residence in our DNA, the past can provide important clues about how to treat them. ...> Full Article Men Unaware of Their Risk of Cancer When Female Family Members Test Positive for Cancer-Causing Gene Mutation (12/17/2007)Men whose mothers, sisters or daughters test positive for a cancer-causing gene mutation also have an increased risk of developing the disease but are unaware of that risk. That is the conclusion of a study at Fox Chase Cancer Center exploring how families communicate genetic test results. ...> Full Article A drink to healthy aging (12/17/2007)A study by the University's Priority Research Centre for Gender, Health and Ageing, in collaboration with the Hunter Medical Research Institute's (HMRI) Public Health Program, indicates that moderate consumption of alcohol in older women, in line with Australian alcohol guidelines*, is associated with better survival and quality of life. ...> Full Article Sperm's immune-protection properties could provide link to how cancers spread (12/17/2007)Sugar-based markers on human sperm cells which may prevent them from being attacked by the female immune system could provide a vital clue to how some cancers spread in the human body ...> Full Article New technique reveals insights into lung disease (12/16/2007)Doctors at the Universities of Nottingham and Leicester are collaborating in the use of a magnetic resonance technique to image and quantify the air spaces inside the lungs - and the results of their research may lead to a link between childhood disease and later degenerative lung disease. ...> Full Article New Marker To Identify Cancer Stem Cells Discovered (12/16/2007)
Scientists Discover Reasons Behind Cancerous Cellular Interactions (12/16/2007)Cellular processes, such as when to multiply, are often regulated by switches that control the frequency and timing of interactions between proteins. North Carolina State University scientists have discovered the way in which a specific protein-protein interaction prevents the cell from turning one of its switches off, leading to uncontrolled cell proliferation - one of the hallmarks of cancer. ...> Full Article Blood Pressure Drug Telmisartan Shows Powerful Activity Against Stroke (12/16/2007)Drug, Alone or in Combination, Eliminated Stroke Risk, Weill Cornell Team Reports ...> Full Article New High-tech Tool For Brain Disorders, Gamma Knife, Now In Use (12/15/2007)
Drug-Coated Stents Beneficial to Heart Patients (12/15/2007)A study by Heart Center cardiologists at Wake Forest University Baptist Medical Center indicates that drug-coated stents are more beneficial than harmful in keeping the arteries of chest pain patients clear of blood clots. ...> Full Article Scientists find how bacteria in cows milk may cause Crohn's disease (12/15/2007)Scientists at the University of Liverpool have found how a bacterium, known to cause illness in cattle, may cause Crohn's disease in humans. ...> Full Article Most carriers of Fanconi anemia genes are not at a higher risk of cancer (12/15/2007)For almost 50 years, Fanconi anemia has been associated with leukemia. Not just among those who have the genetic disorder but among their family members, whose genes, they were told, made them highly susceptible to a variety of malignancies. But a new study to examine links between 13 specific Fanconi anemia genes and cancer risk has determined that in most cases, their risk of cancer is no greater than that of the rest of the population. ...> Full Article Center takes on North American battle against multidrug-resistant tuberculosis (12/15/2007)Multidrug- resistant tuberculosis has a new challenger, a center in the Purdue Research Park that on Tuesday (Dec. 11) became the sole North American producer of a potent antibiotic. ...> Full Article Hormone Fuels Certain Cancer Mutation (12/15/2007)A researcher has discovered that a particular hormone is responsible for driving a cancer enzyme to cause an often deadly red blood cell cancer. ...> Full Article Too much fructose could leave dieters sugar shocked (12/14/2007)Here's one tip for how to eat at the holidays: Don't take your cues from Santa. The sugary cookies and fat-laden fruitcakes the mythical North Pole resident eats are a no-no. But you don't have to go no-carb to stay fit at the holidays, either, University of Florida researchers say. ...> Full Article Seeking to create better drugs, researchers chip away at how tuberculosis survives inside human defense cells (12/14/2007)
Researchers Continue Studies Using Bone Marrow Stem Cells to Treat Heart Attacks (12/14/2007)Doctors at Emory University, in clinical studies with heart attack patients, are continuing to learn more about how those patients' own bone marrow stem cells (progenitor cells) may be used to improve heart function. ...> Full Article How the anthrax bacterium eludes our immune defenses (12/14/2007)After having demonstrated the protective role of one of the enzymes of our natural immunity of against B. anthracis, the anthrax bacterium, researchers from the Institut Pasteur, INSERM, and the CNRS explain how the bacillus is capable of evading the bactericidal action of this enzyme: this bacterium produces a toxin that inhibits the enzyme synthesis. This research*, published in PloS Pathogens, reveals potential new therapeutic avenues against anthrax. ...> Full Article New study reveals for first time how BRCA1 mutations cause breast cancer (12/14/2007)Finding Implicates Tumor Suppressor Gene, PTEN Columbia University Medical Center among Two Institutions to Identify this Gene in 1997 ...> Full Article Missing protein provides clue to ovarian cancer drug success (12/14/2007)Cambridge scientists have discovered a protein which could improve the success rate of the tumour shrinking drug paclitaxel, in the treatment of ovarian cancer, a study reveals in Cancer Cell today. ...> Full Article Gentler Chemotherapy Before Blood Stem Cell Transplant Causes Long-Term Complete Remission in Relapsed Follicular Lymphoma Patients (12/13/2007)Treating relapsed follicular lymphoma patients with a milder chemotherapy regimen before they receive a blood stem cell transplant from a donor resulted in long-term complete remission for 45 of 47 patients in a clinical trial, researchers at The University of Texas M. D. Anderson Cancer Center report at the 49th annual meeting of the American Society of Hematology Meeting in Atlanta. ...> Full Article Silencing small but mighty cancer inhibitors (12/13/2007)Researchers from Johns Hopkins and the University of Pennsylvania have uncovered another reason why one of the most commonly activated proteins in cancer is in fact so dangerous. As reported in Nature Genetics this week, the Myc protein can stop the production of at least 13 microRNAs, small pieces of nucleic acid that help control which genes are turned on and off. ...> Full Article Researchers seeking participants for West Nile Virus study (12/13/2007)If you think West Nile Virus isn't a threat during the fall and winter months, think again. With temperatures being milder during the fall in South Texas, mosquitoes are still active, and that means they're still biting. In some cases, patients diagnosed with the illness during the winter acquire it while traveling through more tropical areas of the world. ...> Full Article Success Continues in Patients Two Years after Constraint-Induced Stroke Therapy (12/13/2007)Stroke patients with mild to moderate impairments substantially regained use of upper limb function and show an improved quality of life two years after receiving constraint-induced movement therapy (CIMT). The findings, reported by Emory University researchers, appear online and in the January issue of The Lancet Neurology. ...> Full Article Keeping at-risk cells from developing cancer (12/12/2007)Researchers at Johns Hopkins have discovered that cancers arising from epigenetic changes - in this case the inappropriate activation of a normally silent gene - develop by becoming addicted to certain growth factors. Reporting online in next week's Early Edition of the Proceedings of the National Academies of Sciences, the team shows that blocking this "addiction" can greatly prevent cancer growth. ...> Full Article Study Finds Gene Linked to Aggressive Prostate Cancer (12/12/2007)Results from two genome-wide association studies have identified a genetic variant of the DAB2IP gene that is associated with the risk of aggressive prostate cancer. Research teams from the Translational Genomics Research Institute (TGen), Wake Forest University School of Medicine, the Karolinska Institute in Stockholm, Sweden, and Johns Hopkins Medical Institutions made the discovery jointly. ...> Full Article Research says Diabetics Most at Risk from Neglected Post Meal Sugar Peak (12/12/2007)Christmas time is full of food when most of us simply have to worry about our expanding waist lines but new research led by the University of Warwick's Medical School says that people with diabetes need to pay attention to the dangers of a neglected post meal peak in blood glucose. Indeed the research shows that this post meal peak can do even more damage than a more sustained rise in blood sugar. ...> Full Article Scientists develop new drug to outflank cancer resistance (12/12/2007)A new drug has shown promising results against breast and prostate cancer cells and tumours that are resistant to conventional hormone-based treatments, according to research published in the British Journal of Cancer* today. ...> Full Article Weight Gain and the Growing Risk of Cancer (12/11/2007)During this holiday season with its tempting bounty of edible delights, new research calls attention to the role of the expanding American waistline in health and medicine. ...> Full Article Promising Approach To A More Effective Sunscreen (12/11/2007)Chronic exposure to the sun increases the risk of an individual developing skin cancer because UV light from the sun can cause genetic mutations that enable cells in the skin to grow in an uncontrolled manner. ...> Full Article Researcher pioneers technology in study of life-threatening illnesses (12/11/2007)In researching diseases such as cancer and multiple sclerosis, immunologists mostly have had to observe static immune cells in laboratories-until now. Alex Huang, a pediatric oncologist with the Department of Pediatrics at Case Western Reserve University School of Medicine, is using advanced laser technology and computer software to capture 3-D, high definition movies of cell interaction in real time. ...> Full Article Leukemia Survival and Pharmacogenetics (12/11/2007)
New Chimeric Mouse Model For Human Liver Diseases, Drug Testing (12/10/2007)
Researcher finds mechanism for faulty protein disposal (12/10/2007)A discovery by St. Jude Children's Research Hospital scientists offers new insights into how myeloma cells dispose of defective or excess proteins and could lead to new cancer treatments. ...> Full Article Scientists Find White Blood Cells Deliver Boost to Tumors (12/10/2007)New Findings Point to Potential New Cancer Targets ...> Full Article Breast MRI spots other cancers, may alter treatment plan (12/10/2007)In about 20 percent of women with breast cancer who plan to undergo a lumpectomy, breast magnetic resonance imaging reveals important diagnostic information that alters their treatment plan, University of Florida surgeons reported today (Dec. 5). ...> Full Article Researchers discover cancer cells 'feel' much softer than normal cells (12/9/2007)Nanotechnology method may help doctors detect and treat cancer more effectively ...> Full Article New Evidence for the Protective Effects of Fruits and Veggies (12/9/2007)The age-old refrain, "Eat your vegetables!" gets scientific support as researchers present the latest findings on cancer prevention at the American Association for Cancer Research's Sixth Annual International Conference on Frontiers in Cancer Prevention, being held December 5 - 8 in Philadelphia, Pennsylvania. ...> Full Article Fish oil prevents pathologies associated with obesity (12/9/2007)According to new research, a diet rich in fish oils may prevent, even reverse, pathologies associated with obesity ...> Full Article Cells use Velcro-like mechanism to keep viruses from spreading (12/9/2007)Like mobsters, cells keep their friends close and their enemies - at least some of them - closer. According to new results from HIV researchers at Rockefeller University, one way that human cells prevent certain viruses from raging out of control is by blocking new viral particles from ever leaving an infected cell's surface. And, they believe, HIV thrives in part because it has evolved the ability to get around this obstacle. ...> Full Article Findings on Plant-derived Cancer Medicines (12/8/2007)The next cancer-fighting therapeutic could be growing in your garden, according to research presented today, at the American Association for Cancer Research's Sixth Annual International Conference on Frontiers in Cancer Prevention Research, being held from December 5 to 8 in Philadelphia, Pennsylvania. ...> Full Article Replacing The Cells Lost In Parkinson Disease (12/8/2007)Parkinson disease (PD) is caused by the progressive degeneration of brain cells known as dopamine (DA) cells. ...> Full Article Scientists strike blow in super bugs struggle (12/8/2007)Scientists have pioneered new ways of tweaking the molecular structure of antibiotics - an innovation that could be crucial in the fight against powerful super bugs. ...> Full Article Herbal extract found to increase lifespan (12/8/2007)
A New Protein Found in the Blood May Provide Relief from Neuropathic Pain (12/7/2007)Neuropathic pain is caused by injury to the peripheral nerves in diseases such as HIV/AIDS, shingles, and cancer or in repetitive motion disorders and trauma, and does not respond well to conventional pain-relieving drugs. Research in rodents by scientists from the University of California, San Diego (UCSD) School of Medicine has provided evidence that a protein called LRP1 may help to ease neuropathic pain by blocking the response of glial cells that support and protect sensory neurons in the peripheral nervous system. Their findings, which could represent a novel target for neuropathic pain therapy, are published in the December 3 issue of the Journal of Clinical Investigation. ...> Full Article The mouse that roared (12/7/2007)How do complex networks of genes control obesity, cancer and heart disease? The unique rodents of the Oklahoma Medical Research Foundation may hold the answer. ...> Full Article New marker identifies cancer stem cells (12/7/2007)Marker corresponds to worse outcomes, could help determine treatments ...> Full Article Blood Flow In Cervical Tumors Can Predict Outcome (12/6/2007)Measuring both the level of red blood cells in the body and the blood flow in tumors can help predict which cervical cancer patients are likely to have a better outcome, according to researchers at the Ohio State University Comprehensive Cancer Center. ...> Full Article Gene variant behind diabetes confirmed (12/6/2007)Certain forms of the WFS1 gene that influence the risk of type 2 diabetes - also called adult-onset diabetes- have been confirmed for the first time by an international team of scientists led by Umeå University researcher Paul W. Franks. The findings have been published in the high-ranking diabetes journal, Diabetologia. ...> Full Article Study finds fitness level, not body fat, may be stronger predictor of longevity for older adults (12/6/2007)Adults over age 60 who had higher levels of cardiorespiratory fitness lived longer than unfit adults, independent of their levels of body fat, according to a study in the December 5 issue of JAMA. ...> Full Article Waistline growth on high-carb diets linked to liver gene (12/5/2007)
Researchers Find That A Commonly Found Contaminant May Harm Nursing Infants (12/5/2007)Scientists have shown that perchlorate-an industrial pollutant linked to thyroid ailments-is actively concentrated in breast milk. Their findings suggest that perchlorate contamination of drinking water may pose a greater health risk than previously realized. ...> Full Article New Drug Has Potential to Treat Hypertension and Heart Disease (12/5/2007)Investigators at the University of California, San Diego (UCSD) School of Medicine have developed a new drug called nitrosyl-cobinamide, which they have shown in animal models to be potentially more effective than nitroglycerin in increasing coronary blood flow and lowering blood pressure. The report on this study, led by Gerry R. Boss, M.D., UCSD professor of medicine, is currently on line and will be published in the December 7 issue of Experimental Biology and Medicine. ...> Full Article Colon Cancer Screenings May Not Payoff and Could Pose Harm to Some (12/4/2007)Even though current guidelines advocate colorectal cancer screenings for those with severe illnesses, they may bring little benefit and may actually pose harm, according to a recent study by Yale School of Medicine researchers published in the Archives of Internal Medicine. ...> Full Article Could hydrogen sulfide hold the key to a long life? (12/4/2007)Study finds 'rotten egg' chemical increases life span and heat tolerance in worms ...> Full Article Decoy makes sitting duck of superbugs (12/4/2007)A DNA-based therapy could slash the development time of new drugs to combat antibiotic resistant superbugs. ...> Full Article Genes identified that protect against heart damage from chemotherapy (12/4/2007)A series of genes that protect cells from the powerful, common chemotherapeutic agent doxorubicin has been identified by researchers working to understand how the drug also can destroy the heart. ...> Full Article Aerosol Launches Immune Response in Lungs to Wipe Out Lethal Infections (12/4/2007)Preclinical research presented at ASCB shows swift killing of bacteria, viruses, fungi ...> Full Article Ovarian Cancer Test Could Save Lives by Detecting Deadly Illness in Stage One (12/4/2007)An aggressive, silent killer of women could soon be caught and identified much faster thanks to new technology developed at the University of South Florida. ...> Full Article 'Superbug' infections more than doubled in hospitals, study finds (12/3/2007)Hospitalizations related to a potentially deadly, antibiotic-resistant "superbug" more than doubled between 1999 and 2005, soaring from 127,000 to nearly 280,000, according to a new study co-authored by a University of Florida researcher. ...> Full Article Exposure to PCBs and Chlorinated Pesticides Linked to Diabetes Among Mohawk Population (12/3/2007)Exposure to polychlorinated biphenyls (PCBs) and chlorinated pesticides may cause diabetes, according to a study by researchers at the University at Albany's School of Public Health. The study, published in Environmental Health Perspectives (Vol. 115, Issue 10, October 2007), found that there was a nearly four times greater risk of diabetes in Mohawks who had PCB levels in the top one-third of the study population. ...> Full Article Non-whites at higher risk for pain with metastatic breast cancer (12/3/2007)A new study finds significant racial differences in the risk of pain related to metastatic breast cancer. An analysis by Dr. Liana Castel of the University of North Carolina at Chapel Hill and colleagues found that non-whites experience poorer pain control among women with this disease. ...> Full Article Biochemist Stares Down Superbug (12/3/2007)University of Victoria biochemist Dr. Alisdair Boraston has discovered something new about a nasty superbug-a discovery that could lead to new drugs to combat it. ...> Full Article DNA Methylation Shown To Promote Development Of Colon Tumors (12/2/2007)Damaged or defective genes have long been known to be the cause of some cancers. Over the past decade, however, scientists have discovered that even healthy genes can be switched on or off and can cause cancer without any changes in the underlying DNA sequence--although how this happens has remained poorly understood. ...> Full Article Researchers produce short-term reversal of skin aging in mice (12/2/2007)Researchers have reversed the effects of aging on the skin of mice, at least for a short period, by blocking the action of a single critical protein. ...> Full Article New study finds that sleep duration raises the risk for diabetes (12/2/2007)The most common factors believed to contribute to diabetes are a decreased amount of physical activity and access to highly palatable processed foods. However, there is growing evidence that another aspect of our modern lifestyle, short sleep duration, is also contributing toward the "diabetes epidemic", according to a study published in the December 1 issue of the journal Sleep. ...> Full Article New x-ray technique targets terrorists and tumours (12/2/2007)Scientists at The University of Manchester have developed a new x-ray technique that could be used to detect hidden explosives, drugs and human cancers more effectively. ...> Full Article Radar technology fights breast cancer (12/1/2007)Clinical results using microwave heat treatments are promising ...> Full Article Genomic study of malaria parasite unearths surprising behaviors (12/1/2007)The malaria parasite has been studied for decades, but surprisingly little is known about how it behaves in humans to cause disease. Now an international team including scientists at the Broad Institute of MIT and Harvard has for the first time measured which of the parasite's genes are turned on or off during actual infection in humans, unearthing surprising behaviors and opening a window on the most critical aspects of parasite biology. ...> Full Article New heart test to save time, money - and lives (12/1/2007)A new test could give doctors a head start in diagnosing those patients most likely to suffer a heart attack. ...> Full Article In blood, malaria's secrets revealed (12/1/2007)Study of malaria parasite in patients' blood uncovers biological states never before glimpsed in laboratory-based research ...> Full Article UCSD Offers Free Test That Can Detect HIV as Early as One Week after Exposure (12/1/2007)UC-San Diego's Antiviral Research Center (AVRC) is offering free and confidential HIV testing to people who may have a very recent infection with HIV, the retrovirus that can lead to AIDS. The Early Test Program - offered in collaboration with the San Diego County Health and Human Services Agency - offers a new test method that checks for the presence of the HIV virus, which can be detected within a week of infection. In contrast, a regular HIV test looks for antibodies in the blood, which can take three months or more to detect. ...> Full Article |
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Protein shown to be natural inhibitor of aging in fruit fly model
New testing method hints at garlic's cancer-fighting potential
New biomarkers for predicting the spread of colon cancer
Cells of aggressive leukemia hijack normal protein to grow
The sound of melanoma can help doctors find cancer
Bitter melon extract attacks breast cancer cells
Scanning for skin cancer: Infrared system looks for deadly melanoma