Curing Death by Curing Disease, Cancer & Aging
A group of researchers led by the Institute of Biotechnology and Biomedicine and Universitat Autonoma de Barcelona have achieved to quantify with precision the effect of protein aggregation on cell aging processes using as models the Escherichia coli bacteria and the molecule which triggers Alzheimer's disease. Scientists demonstrated that the effect can be predicted before it occurs. Protein aggregation is related to several diseases, including neurodegenerative diseases.
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Minuscule amounts of ethanol can at least double the life span of a tiny worm used as a model for aging studies, UCLA biochemists report. "This finding floored us; it's shocking" said Steven Clarke, UCLA professor of chemistry and biochemistry, and senior author of the study.
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While environment and family history are factors in healthy aging, genetic variants play a critical and complex role in conferring exceptional longevity, according to researchers from the Boston University Schools of Public Health and Medicine, Boston Medical Center, IRCCS Multimedica in Milan, Italy, and Yale University.
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Modified probiotics, the beneficial bacteria touted for their role in digestive health, could one day decrease the risk of Listeria infection in people with susceptible immune systems, according to Purdue University research.
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Mice bred to age too quickly seemed to have sipped from the fountain of youth after scientists at the University of Pittsburgh School of Medicine injected them with stem cell-like progenitor cells derived from the muscle of young, healthy animals. Instead of becoming infirm and dying early as untreated mice did, animals that got the stem/progenitor cells improved their health and lived two to three times longer than expected, according to findings in Nature Communications.
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 | A Mediterranean diet with large amounts of vegetables and fish gives a longer life. This is the unanimous result of four studies to be published by the Sahlgrenska Academy at the University of Gothenburg. Research studies ever since the 1950s have shown that a Mediterranean diet, based on a high consumption of fish and vegetables and a low consumption of animal-based products such as meat and milk, leads to better health. ...> Full Article |
Contrary to claims that US presidents age at twice the normal rate, a new study by noted UIC demographer S. Jay Olshansky finds that most US presidents live longer than expected for men of their same age and era.
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Reproductive and somatic aging use different molecular mechanisms that show little overlap between types of genes that keep oocytes healthy and genes that generally extend life span.
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Collaborations between Johns Hopkins and National Taiwan University researchers have successfully manipulated the life span of common, single-celled yeast organisms by figuring out how to remove and restore protein functions related to yeast aging.
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Scientists at the University of Liverpool have identified high levels of a number of genes in the naked mole-rat that may suggest why they live longer than other rodents and demonstrate resistance to age-related diseases.
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 | One of the few reliable ways to extend an organism's lifespan, be it a fruit fly or a mouse, is to restrict calorie intake. Now, a new study in fruit flies is helping to explain why such minimal diets are linked to longevity and offering clues to the effects of aging on stem cell behavior. ...> Full Article |
Inserm's AVENIR "Genomic plasticity and aging" team, directed by Jean-Marc Lemaitre, Inserm researcher at the Functional Genomics Institute, has recently succeeded in rejuvenating cells from elderly donors (aged over 100).
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Researchers have identified a potential drug therapy for a premature aging disease that affects children causing them to age up to eight times as fast as the usual rate.
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 | By consuming fewer calories, aging can be slowed down and the development of age-related diseases such as cancer and type two diabetes can be delayed. The earlier calorie intake is reduced, the greater the effect. Researchers at the University of Gothenburg have now identified one of the enzymes that hold the key to the aging process. ...> Full Article |
Health prevention strategies to help Canadians achieve their optimal health potential could add a decade or more of healthy years to the average lifespan and save the economy billions of dollars as a result of reduced cardiovascular disease, says noted cardiologist Dr. Clyde Yancy.
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