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Calico enters into exclusive collaboration with 2M to develop UTSW technology (9/14/2014)

UT Southwestern Medical Center, 2M Companies, and Calico today announce a new collaboration to advance research and drug development for neurodegenerative disorders caused by the aging and death of nerve cells. ...> Full Article


Less effective DNA repair process takes over as mice age (9/12/2014)

Biologists Vera Gorbunova and Andei Seluanov have discovered one reason for increasing DNA damage in older vertebrates: the primary repair process begins to fail with increasing age and is replaced by one that is less accurate. ...> Full Article


Biologists delay the aging process by 'remote control' (9/11/2014)

Biologists delay the aging process by 'remote control'UCLA biologists have identified a gene that can slow the aging process when activated remotely in key organ systems. The life scientists, working with fruit flies, activated a gene called AMPK that is a key energy sensor in cells. Increasing AMPK in the intestine increased the fly's life by about 30 percent, and the fly stayed healthier longer as well. The research could have important implications for delaying aging and disease in humans. ...> Full Article


Curb sitting time to protect aging DNA and possibly extend lifespan (9/5/2014)

Curbing the amount of time spent sitting down might help to protect aging DNA and therefore possibly extend the lifespan, suggests a small study published online in the British Journal of Sports Medicine. ...> Full Article


Researching fundamental rhythms of life (8/31/2014)

Casey Diekman, assistant professor of mathematical sciences at New Jersey Institute of Technology, is helping to gain greater insight into the biological clock that sets the pace for daily life. ...> Full Article


APOB, a gene involved in lipid transport, linked to cases of familial extreme longevity (8/30/2014)

In a recent report in Aging Cell, a multidisciplinary team of Spanish scientists, led by Tim Cash and Manuel Serrano at the Spanish National Cancer Research Centre, identify rare variants in the APOB gene in several families where exceptional longevity (>100 years of age) appears to cluster. ...> Full Article


Are you as old as what you eat? Researchers learn how to rejuvenate aging immune cells (8/28/2014)

Researchers from UCL have demonstrated how an interplay between nutrition, metabolism and immunity is involved in the process of aging. ...> Full Article


Taking the pulse of aging (8/20/2014)

In an effort to identify how the elasticity of the arteries in the brain correlates with aging well, researchers at the Beckman Institute used optical methods developed in their lab to map out the pulse pressure of the entire brain's cortex. ...> Full Article


Analysis of African plant reveals possible treatment for aging brain (8/6/2014)

Analysis of African plant reveals possible treatment for aging brainSalk scientists find that a plant used for centuries by healers of São Tomé e Príncipe holds lessons for modern medicine. ...> Full Article


The 'memory' of starvation is in your genes (8/5/2014)

Epigenetic 'experiments' -- changes resulting from external rather than genetic influences -- suggest that the body's physiological responses to hardship could be inherited, although the underlying mechanism has been a mystery. Now researchers from Tel Aviv University have discovered a genetic mechanism that passes on the body's response to starvation to subsequent generations of worms, with potential implications for humans also exposed to starvation and other physiological challenges. ...> Full Article


Key to aging immune system is discovered (8/4/2014)

Key to aging immune system is discoveredThe immune system ages and weakens with time, making the elderly prone to life-threatening infection and other maladies, and a UC San Francisco research team now has discovered a reason why. ...> Full Article


Strategy proposed for preventing diseases of aging (7/25/2014)

Strategy proposed for preventing diseases of agingResearchers at Washington University School of Medicine in St. Louis and elsewhere argue that medicine focuses too much on fighting diseases individually instead of concentrating on interventions that prevent multiple chronic diseases and extend healthy lifespan. They call for moving forward with strategies that have been shown to delay aging in animals. In addition to promoting a healthy diet and regular exercise, these strategies include manipulating molecular pathways that slow aging and promote healthy longevity. ...> Full Article


Scientists identify gene that plays a surprising role in combating aging (7/22/2014)

Scientists identify gene that plays a surprising role in combating agingScientists from the Florida campus of The Scripps Research Institute have found in animal models that a single gene plays a surprising role in aging that can be detected early in development, a discovery that could point toward the possibility of one day using therapeutics, even some commonly used ones, to manipulate the aging process itself. ...> Full Article


Preconceptional factors in the prediction of fertility and the reproductive lifespan (7/9/2014)

A project in Denmark whose aim is to assess the reliability of preconceptional lifestyle and biological factors as predictors of fertility has found a pronounced effect of the contraceptive pill on markers used to assess 'ovarian reserve,' a predictor of future reproductive lifespan. ...> Full Article


Reproduction later in life is a marker for longevity in women (7/1/2014)

Women who are able to naturally have children later in life tend to live longer and the genetic variants that allow them to do so might also facilitate exceptionally long life spans, according to a Boston University School of Medicine study. ...> Full Article

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New Articles
Calico enters into exclusive collaboration with 2M to develop UTSW technology

Less effective DNA repair process takes over as mice age

Biologists delay the aging process by 'remote control'Biologists delay the aging process by 'remote control'

Curb sitting time to protect aging DNA and possibly extend lifespan

Researching fundamental rhythms of life

APOB, a gene involved in lipid transport, linked to cases of familial extreme longevity

Are you as old as what you eat? Researchers learn how to rejuvenate aging immune cells

Taking the pulse of aging

Analysis of African plant reveals possible treatment for aging brainAnalysis of African plant reveals possible treatment for aging brain

The 'memory' of starvation is in your genes

Key to aging immune system is discoveredKey to aging immune system is discovered

Strategy proposed for preventing diseases of agingStrategy proposed for preventing diseases of aging

Scientists identify gene that plays a surprising role in combating agingScientists identify gene that plays a surprising role in combating aging

Preconceptional factors in the prediction of fertility and the reproductive lifespan

Reproduction later in life is a marker for longevity in women



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